normal anatomy and physiology of the central nervous system

... illustrates redundancy in the chemokine system. Although some of the data on the role of CCR5 in the pathogenesis of MS and EAE appears to be conflicting, the weight of evidence identifies CCR5 ... purposes) macrophages and resident microglia to sites of CNS inflammation. Detailed knowledge of expression patterns is crucial for the understanding of therapeutic modulation and the validation of CCR1, CCR2 and ... immu- noneutralization of CCL3 [44], DNA vaccination [45], or genomic deletion of the CCR1 gene [22], reduces clinical disease. Taken together, the results of the present study and from previous ones on the role of...

Ngày tải lên: 19/06/2014, 22:20

Ngày tải lên: 09/08/2014, 02:20

Ngày tải lên: 07/08/2014, 14:23

... various combinations of chemotherapy and cranial radiation. The excellent correlation of the in vitro and in vivo results of Noble and colleagues’ study [1] raises the hope that the technique used ... G: Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treat- ment of the central nervous system with radiation and intrathecal chemotherapy. ... this very young, and hence vulnerable, population of patients. Chemotherapy-induced cognitive decline in the absence of radiation The best data on the cognitive effects of chemotherapy alone have...

Ngày tải lên: 06/08/2014, 18:21

... that should prove of great value in the discovery and evaluation of therapies that either allow selective killing of cancer cells or offer selective protection to the normal cells of the body. MMaatteerriiaallss ... markedly decreased levels of MBP in the CC and in the white-matter tracts of the striatum of treated animals (Figure 10). In agreement with the majority of the cell bodies in the mature CC belonging ... oligodendrocytes and extensive myelin pathology. Functional analysis also provided the first demonstration of delayed effects of chemotherapy on the latency of impulse conduction in the auditory system, offering...

Ngày tải lên: 06/08/2014, 18:21

Ngày tải lên: 11/08/2014, 00:22

Ngày tải lên: 23/03/2014, 01:20

... cover of only 48 examples out of the 92 variants in the corpus. The active corpus treated separately requires 38 examples out of 46 and the passive corpus requires 28 out of 46. Treating the ... for inducing the language. Though the minimal number of examples is of course unique, the set of particular strings in the covering sample is not necesm~rily Imique. INFERENCE OF THE ENGLISH ... overgeneralizes the full corpus as well as the active and passive corpora treated as separate languages. For the active corpus, zero-reversible inference groups the forms of do with the other modals. The...

Ngày tải lên: 24/03/2014, 01:21

... the emer- gence of the Plathelminthes in the evolutionary his- tory. The eye of the planarian is one of the most ancestral and primitive types of visual systems in animals and is of particular ... one of the simplest animal groups with a central nervous system. Their primitive central nervous system produces large quantities of a variety of neuropeptides, of which many are amidated at their C ... in the planarian cen- tral nervous system to support the PHM activity and that it predates the emergence of Plathelminthes in the evolutionary history. Abbreviations AsA, ascorbic acid; CNS, central...

Ngày tải lên: 30/03/2014, 15:20

... amounts of norepinephrine within the hypothalamus and in certain zones of the limbic system, such as the central nucleus of the amygdala and the dentate gyrus of the hippocampus. However, this ... Management of the anesthetic interplays constantly with the general physiology of the patient. Historically, and continuing to the present, the great majority of cases involves the administration of ... loss of the agent from the arterial blood to all the tissues of the body. Obviously, the concentration in neural tissues is of greatest importance. The details of the uptake and distribution of...

Ngày tải lên: 12/07/2014, 20:21

... after injection. They found a more persistent suppression of proliferation in regions of the brain where proliferation is essential to normal function (the subventricular zone, the dentate gyrus of the hippocampus ... also found that the agents caused increased cell death and decreased cell division in the subventricular zone, the dentate gyrus of the hippocampus and the corpus callosum in mice. These effects ... understanding of the mechanisms of acute and, importantly, progressive and delayed injury to the brain from clinically relevant short-term exposure to a widely used chemotherapy agent. Furthermore,...

Ngày tải lên: 06/08/2014, 18:21

Ngày tải lên: 09/08/2014, 10:21

... Barnholtz-Sloan, Andrew E. Sloan, and Ann G. Schwartz Chapter 25 Cancer of the Brain and Other Central Nervous System Chapter 25 Cancer of the Brain and Nervous System National Cancer Institute ... patterns of care of brain tumor patients in the United States: a study of the Brain Tumor Section of the AANS and the CNS and the Commission on Cancer of the ACS. Clin Neurosurg 1990;36:347-52. 12. ... Chapter 25 Cancer of the Brain and Nervous System other. For all race specific analyses, only white and black patients are used because the other category is made up of a mix of racial groups....

Ngày tải lên: 22/03/2014, 17:20

Ngày tải lên: 11/08/2014, 03:20