ystematic assessment of protein interaction data using graph topology approaches

... Jin Chen 2006 Systematic Assessment of Protein Interaction Data using Graph Topology Approaches by Jin Chen, B.Eng Dissertation Presented to the Faculty of the School of Computing of the National ... of Singapore in Partial Fulfillment of the Requirements for the Degree of DOCTOR OF PHILOSOPHY National University of Singapore October 2006 Systematic Assessmen...

Ngày tải lên: 14/09/2015, 18:02

... completeness of information obtained from abstracts in comparison to the full-length articles as a measure of reliability of abstracts as sources of protein interaction data METHODS Selection of articles ... (proprietary protein interactions maps database from Jubilant Biosys Ltd.) was used IMaps is a manually curated database with more than 200 000 protein- protein,...

Ngày tải lên: 22/06/2014, 19:20

... represented by a directed graph Measured protein interaction data are represented by a directed graph The graph shows the interaction data between four selected proteins from the report by Krogan and ... cell For the Y2 H system, analyses conducted separately by Walhout and coworkers [31], Mrowka and colleagues [19], and Aloy and Russell [32] have reported...

Ngày tải lên: 14/08/2014, 08:20

... represent the grouping of objects They have two distinct types of nodes, and edges only connect a node of one type to a node of the other For example, the proteins of a biological system could be the ... question of whether or not they interact can be answered as either yes or no The aim of making a measurement is to record the true, typically unknown, value of a p...

Ngày tải lên: 14/08/2014, 08:20

... aspects of the control of signaling by protein phosphorylation The abundance of high-quality data confirms that quantitative MS is here to stay and is already making key contributions to most areas ... responsible for the binding and extends the scope of the classic yeast two-hybrid experiment, which is only able to detect whether two fulllength proteins interact Probably...

Ngày tải lên: 14/08/2014, 08:20

... system [13], either by measurement of the rate of production of O2– or the rate of O2 uptake INT diaphorase activity was assayed by the rate of reduction of INT into formazan in the presence of ... The quantity of neutrophil membranes used in the oxygraphic assays was 10 · that used in the photometric assay For measurement of the Km of activated oxid...

Ngày tải lên: 31/03/2014, 21:21

... the adaptive NC is presented for fusion of shifted image sequences, the algorithm is applicable to any problem of fusion of irregularly sampled signals Not only useful in fusion of irregularly sampled ... analysis The effectiveness of robust fusion using adaptive NC has been demonstrated through the application of superresolution reconstruction of LR image s...

Ngày tải lên: 22/06/2014, 23:20

... Figure Visualization of one-dimensional self-organizing map after clustering Visualization of one-dimensional self-organizing map after clustering 1D-SOM matrix after metabolite-based clustering ... metabolite-based clustering and visualization of large sets of metabolic marker candidates based on self-organizing maps (SOMs) Unlike applications of the class...

Ngày tải lên: 12/08/2014, 17:20

... peptide/ protein profiling Proteomics 2007, 7:3470-80 doi:10.1186/1559-0275-8-6 Cite this article as: Borg et al.: Spectral counting assessment of protein dynamic range in cerebrospinal fluid following ... manual inspection of the protein list not identified in samples subjected to IgY14 depletion indicates that 13 proteins (out of 24) were removed by IgY14 col...

Ngày tải lên: 13/08/2014, 13:20

... replicated 10 times Simulated rather than real data were used because a negative diagnosis, even based on the absence of bacteria in cell culture, is not a guarantee of health and the opposite has ... that the mixed HMM provides a good t to the data sets simulated in this study The advantages of the HMM over other approaches are the prediction of health or d...

Ngày tải lên: 14/08/2014, 13:21

... his installation of Stan in Linux server I also thank other colleagues of mine for their encouragement v Baoguang Han STATISTICAL ANALYSIS OF CLINICAL TRIAL DATA USING MONTE CARLO METHODS In medical ... METHODS In medical research, data analysis often requires complex statistical methods where no closed-form solutions are available Under such circumstances,...

Ngày tải lên: 24/08/2014, 11:40

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 01/10/2015, 17:27

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 03/10/2015, 21:56

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 04/10/2015, 07:57

... identify the strength of the individual linkage by determining the relative importance of the linkage types The goal is at the top of the model 4.4.2 The Actors Like the AHP model formulated for overall ... involvement in the process of technological assessment The objective of this study is to apply the Analytic Hierarchy Process (AHP) for...

Ngày tải lên: 23/04/2013, 10:29