The function of TOM1 l1 in bridging EGFR signaling and endocytosis

... THE FUNCTION OF TOM1- L1 IN BRIDGING EGFR SIGNALING AND ENDOCYTOSIS LIU NINGSHENG (M.Med Southeast Univ.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY INSTITUTE OF MOLECULAR AND ... Cloning and Sequencing 2.2 Plasmid Constructs 2.2.1 HA -TOM1- L1, HA -TOM1- L1 Y460F and GFP -TOM1- L1 2.2.2 HA -TOM1- L1 SH3, HA -TOM1- L1 Y392F and HA -...

Ngày tải lên: 14/09/2015, 08:41

... consider these devices as clues, but examine the relations between the use of anaphors and clues in the next section Even w!thin the classification of connectives, there is a question of level of explicitness ... indicating a causal connection, but c) requires a kind of referent resolution as 254 structure reconstruction also allows us to comment on the the function o...

Ngày tải lên: 08/03/2014, 18:20

... accordingly to the lack of most of the pigment binding sites present in the other Lhc proteins [20,47] Results from Aspinall-O'Dea and coauthors, indicating zeaxanthin binding to PsbS in vitro ... than in the npq4 mutant [9,20] This indicates that the function of PsbS in qE activation is dominant compared to that one of zeaxanthin in the presence of ∆pH I...

Ngày tải lên: 24/06/2015, 08:18

... brings the total known number of kinectin isoforms in mouse to 16 (Fig 1.2) The identification of total of 16 kinectin isoforms reveals the long-suspected existence of a family of kinectin isoforms ... kDa kinectin of Int4 at the leading edge of migrating cells 60 Chapter Roles of kinectin Int4 in ER dynamics during cell migration and division 63...

Ngày tải lên: 08/11/2015, 16:45

... construction, and management of training institutions Outside of the MoH, the Cabinet Office and the Ministry of Finance control the annual budget for all ministries The Ministry of Education and the Ministry ... significant increase in health training institution graduates [5] In response, the Ministry of Health National Training Plan 2008 provided top...

Ngày tải lên: 18/06/2014, 17:20

... ºC min min min min min min min 94 95 93 90 92 RESULTS Germination results of Scots pine and the four undergrowth species (table I) indicate that the four obligatory seeder species (Pinus sylvestris, ... follows Tutin et al [47] Models of germination of competitor species 77 Table I Percentage of germination of Pinus sylvestris and four shrub spe...

Ngày tải lên: 08/08/2014, 01:21

... the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional inactivation of HIF-1α in the presence of interleukin-1β ... the work by Yudoh and colleagues adds further experimental evidence for the suggested role of HIF-1 in protecting chondrocytes from cell death induced by pro-i...

Ngày tải lên: 09/08/2014, 07:20

... attenuated in the γδ T cell deficient mice Our findings are consistent with a role of γδ T cells in determining the magnitude of the inflammatory response to acute epithelial injury and in maintaining ... hyperresponsiveness and exhibit an attenuated inflammatory response The contribution of γδ T cells to epithelial regeneration in the intes...

Ngày tải lên: 12/08/2014, 15:20

... viruses, an "infectious unit" refers to the smallest amount of virus capable of producing an infection in a susceptible cell The titre of the original suspension is defined as the number of infectious ... than half of the active vectors had adsorbed to the cells To estimate the t(1/2) of the vector system used here, we pre-incubated the inoculum for incre...

Ngày tải lên: 14/08/2014, 19:22

... The role of FGFR3 mutation in tumour initiation, progression and invasion of urothelial cell carcinoma in mice Mona Foth Submitted in fulfilment of the requirements for the Degree of PhD ... at the signalling downstream Thirdly, we examined the role of the most common mutation in FGFR3, S249C, in the urothelium and in tumour...

Ngày tải lên: 22/12/2014, 20:56

... through RXR To determine whether the influence of USP ⁄ RXR on the EcR function is mediated at the level of heterodimerization between EcR and USP ⁄ RXR, we Influence of RXR on EcR function Fig Comparison ... performance of HsRXR, LmRXR and the two chimeras, Hs–LmRXR (helix 1–8 of HsRXR and 9–12 of LmRXR) and Lm-HsRXR (helix and two loops on either side of he...

Ngày tải lên: 07/03/2014, 12:20

... activity of  45 mUặmg)1 of protein (Fig 1), whereas in the cell lysate of the parental strain the activity was  50 mUặmg)1 of protein These ndings clearly indicate that the predominant part of F420H2 ... absent in the cytoplasmic fraction of the DfpoF mutant This observation prompted investigation into the function of FpoF in more detail The correspondi...

Ngày tải lên: 14/03/2014, 23:20

... DISCUSSION The findings in this study show that GR is highly expressed in epithelial cells of the male genital tract, especially in the Ó FEBS 2002 Glutathione reductase in male reproduction system ... level of expression of aldose reductase was also detected in the epithelia of the male genital tract In addition, glutathione S-transferase is pre...

Ngày tải lên: 17/03/2014, 17:20

... substitution of D76 by asparagine or leucine resulted in nearly inactive mutants, whereas D76H exhibited about 10% of the wild-type activity of polysulđde respiration The hydroxyl groups of Y2 3 and Y1 59 ... encode the membrane anchor of the enzyme and to carry the site of quinol oxidation Tetrathionate reductase (Ttr) of Salmonella typhimurium is thou...

Ngày tải lên: 24/03/2014, 03:21

... Overview Describe the structure of a network, including the devices and media that are necessary for successful communications Explain the function of protocols in network communications Explain ... be installed – The amount of data and the speed at which it must be transmitted – The cost of the media and installation 17 Local Ar...

Ngày tải lên: 01/04/2014, 12:20