Identification of additional genetic alterations in RUNX1 related leukemias

... transcription activation domain Figure 1.5: RUNX1 domains and interactions A diagram of RUNX1 protein with main functional domains, interacting proteins and sites of phosphorylation and acetylation ... domain Their protein sequences are highly conserved with 22 more than 90% identity in the Runt domain Moreover, all RUNX proteins have PPxY motif, a domain for the binding of WW dom...

Ngày tải lên: 12/09/2015, 08:19

... values of wind direction and wind speed of sample i The ranges of wind direction and wind speed are divided into a series of subranges having similar numbers of samples in each Then each wind direction/ ... concentration of compound j measured in sample i, the concentration of compound j in the emission of source p, and the strength of source p on sample i (16, 19)...

Ngày tải lên: 22/03/2014, 14:20

... reached the bottom of the resolving gel The small triangle of one corner gel was marked so the orientation is not during staining 2.1.4 Gel Staining and Destaining After the completed of the run, gel ... concluded that inoculum of the pathogen originates from infected panicles and affects seedlings from the meristem, with infections descending to lower stem sections and roots Minor in...

Ngày tải lên: 23/03/2014, 22:20

... GGGACAAGTG AAAATGTCTC TTCAGGGGAT TCAGCTTAGT GACTTGTCCT ATAAGCATGC AATCCTTAAA GAATCACAGT ACACAATCAA GGGACAAGTC AAAATGTCTC TTGAAAGTAT TAGACTCAGT GACTTGGAGT ACAAACATGC AATTCTTGAA GACTCTCAGT ATACAATTAG ... CTGAAGTAGG AATGCAGTAC GTGAGCACCA CACCGACTAT GAGCCTGCAG CAGAGGTAGG CATGCAGTAC ATTAGTACTG CACTGGGAGC AGAGCGTACA CAGCAGATAC TAAAGAACTC CTCTAGGAGC TGATAGAACT CAACAAATAC TGAAAAATTC 270 270 aMPV/C/US...

Ngày tải lên: 19/06/2014, 08:20

... GGGACAAGTG AAAATGTCTC TTCAGGGGAT TCAGCTTAGT GACTTGTCCT ATAAGCATGC AATCCTTAAA GAATCACAGT ACACAATCAA GGGACAAGTC AAAATGTCTC TTGAAAGTAT TAGACTCAGT GACTTGGAGT ACAAACATGC AATTCTTGAA GACTCTCAGT ATACAATTAG ... CTGAAGTAGG AATGCAGTAC GTGAGCACCA CACCGACTAT GAGCCTGCAG CAGAGGTAGG CATGCAGTAC ATTAGTACTG CACTGGGAGC AGAGCGTACA CAGCAGATAC TAAAGAACTC CTCTAGGAGC TGATAGAACT CAACAAATAC TGAAAAATTC 270 270 aMPV/C/US...

Ngày tải lên: 20/06/2014, 04:20

... used in this study were suitable for the principal purpose of our study: i.e to determine the putative origin of P pinaster stands in the Aquitaine region of France To our knowledge, the type of ... pathways of maritime pine (Pinus pinaster Ait) in the Iberian peninsula, Theor Appl Genet 100 (2000) 89–95 [30] Sinclair W.T., Morman J.D., Ennos R.A., Multiple origins for...

Ngày tải lên: 08/08/2014, 14:20

... linkers, amplification of targeted DNA, purification of amplified DNA, labeling, hybridization, and scanning The Affymetrix GeneChip® Human Mapping 500K Array was used Scanning and analysis were performed ... subsequently genotyped in patients with Behçet's disease and controls using a case-control genetic association approach and the TaqMan SNP Genotyping Assays (Applied Biosys...

Ngày tải lên: 09/08/2014, 14:20

... Therefore, the unimodal assumption of candidates for selection within an age class is not valid Moreover, the probabilities of origin of each kind of breeding animals (for instance, AI and NS ... efficiency and carcass quality) and maternal performance (eg, fertility and ease of calving) Beef cattle breeding schemes can be efficient despite a small number of insem...

Ngày tải lên: 09/08/2014, 18:21

... recent incomplete xenologous replacements Gene family size in intraspecific and interspecific comparisons The sequencing of several strains of a single species is now common in bacterial genomics ... ATP-binding component of spermidine/putrescine transport and for some reason its amplification has been selected in this species Proteins involved in the transport of spermidi...

Ngày tải lên: 09/08/2014, 20:20

... are expressed in baboon liver and lymphocytes and the differences in these miRNA expression profiles The findings from these studies are relevant to future studies of the roles of miRNAs in dyslipidemia ... putative baboon miRNAs After identifying the baboon miRNAs in- silico, we determined expression profiles of baboon liver and lymphocytes miRNAs using a...

Ngày tải lên: 10/08/2014, 05:21

... value of the molecular detection of circulating tumor cells using a multimarker reverse transcription-PCR assay for cytokeratin 19, mammaglobin A, and HER2 in early breast cancer Clin Cancer ... Value of the Molecular Detection of Circulating Tumor Cells Using a Multimarker Reverse Transcription-PCR Assay for Cytokeratin 19, Mammaglobin A, and HER2 in Early...

Ngày tải lên: 10/08/2014, 22:20

... strong predictor of adverse outcome, but other single genomic alterations, such as loss of 11q or gain of 17q, were overridden by the presence of any kind of segmental alterations in multivariate ... comprised 47% of the tumors, whereas it accounted for 28% of the cases in the study of Caren et al [8] Similar to the latter findings [8], this subgroup constit...

Ngày tải lên: 11/08/2014, 12:20

... as in the initial analysis DNA of organs and tissue supernatants was extracted using the QiAamp tissue kit according to the manufacturer's instructions (Qiagen, Hilden, Germany) Panherpes consensus-PCR ... Beisser PS, Kaptein SJ, Beuken E, Bruggeman CA, Vink C: The Maastricht strain and England strain of rat cytomegalovirus represent different betaherpesvirus species rather than strai...

Ngày tải lên: 12/08/2014, 04:21

... first work studying concerted gene expression of sunflower in response to salinity, allowing the identification of genes involved in common regulatory mechanisms to both Page 11 of 18 (page number ... by salt stress per se In another study the expression of 150 genes in response to wounding and insect feeding was carried out [58], finding that some of the...

Ngày tải lên: 12/08/2014, 05:20

... FXI deficiency in Holstein cattle in Turkey This is the 1st report on the FXI deficiency in Holstein cattle in Turkey The bulls used for artificial insemination should be screened to determine ... associated with factor XI deficiency in Holstein cattle Anim Genet 2004, 35:454-456 Citek J, Rehout V, Hanusova L, Vrabcova P: Sporadic incidence of factor XI...

Ngày tải lên: 12/08/2014, 18:22