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Role of RNA directed DNA methylation in controlling genomic imprinting in arabidopsis thaliana

Role of RNA directed DNA methylation in controlling genomic imprinting in arabidopsis thaliana

Role of RNA directed DNA methylation in controlling genomic imprinting in arabidopsis thaliana

... to the silencing of maternal PHE1 and proper maintenance of the imprinted status of PHE1 in endosperm 26 2.4 Genomic imprinting and RNA- directed DNA methylation Maintenance of DNA methylation ... evolutionary origin of imprinting are still unclear but in plants, imprinting may be the consequence of global epigenetic reprogramming during sexual reproduction Introduction of imprinting In plants ... mechanisms leading to imprinting of maternally expressed genes in Arabidopsis 21 1-8 Long distance cis-elements of imprinted genes 26 1-9 Regulation of PHERES1 imprinting 26 1-10 RNA- directed DNA methylation...
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Báo cáo y học:

Báo cáo y học: "The role of RNA folding free energy in the evolution of the polymerase genes of the influenza A virus" potx

... only one of them was used in the analysis As we explained above, the choice of focusing on the ORF was dictated by the fact that the majority of the sequences in the database contain partial ... independent of the concurrent amino acid changes in the polymerase and NP genes, and independent of the codon usage bias In addition, human influenza A strains have increasingly higher folding energies ... necessarily in the 1957 pandemic) was of avian origin The possibility of an avian influenza A virus strain crossing the host barrier and successfully propagating in humans has been controversial...
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Báo cáo y học:

Báo cáo y học: "ome-wide prediction and identification of cis-natural antisense transcripts in Arabidopsis thaliana" pot

... annotation mainly aims at the identification of protein coding genes within a genome, there is the possibility that non-coding antisense transcripts may be overlooked by currently trained gene finders ... repeat-containing protein - 006-301-C08 J013155K02 Rice DNA topoisomerase VIA PPR repeat-containing protein - At5g54270 Description - Chlorophyll A-B binding protein Myosin heavy chain Chlorophyll A-B binding ... are needed to investigate the validity of these hypotheses Antiparallel transcription and antisense transcripts are known to be involved in genomic imprinting of Xist gene in mouse and human [21]...
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Báo cáo y học:

Báo cáo y học: " Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana" pot

... genes) Genome-wide profiling of H3K4me1, H3K4me2 and H3K4me3 Arabidopsis chromatin enriched for H3K4me was isolated by ChIP using antibodies that specifically recognize H3K4me1, H3K4me2 and H3K4me3 ... associated H3K4me: H3K4me1 only (me1+me2-me3-), H3K4me2 only H3K4me3 only (me1-me2-me3+), (me1-me2+me3-), H3K4me1 and H3K4me2 but no H3K4me3 (me1+me2+me3-), H3K4me1 and H3K4me3 but not H3K4me2 (me1+me2me3+), ... H3K4me1; 3’ % of genes with H3K4me1 in corresponding intervals H3K4me1; 5’ 30 3 -4 kb 40 % of genes with H3K4me3 in corresponding intervals % of genes with H3K4me1 in corresponding intervals 40 ...
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THE ROLE OF DNA METHYLATION IN REGULATING LHX3 GENE EXPRESSION

THE ROLE OF DNA METHYLATION IN REGULATING LHX3 GENE EXPRESSION

... diseases DNA methylation has been implicated in gene regulation in multiple physiological systems This dissertation examines the role of DNA methylation in regulating the murine Lhx3 gene To determine ... further define both the interaction of the LHX3 C-terminus with the chromatin regulators, as well as regulation of the Lhx3 gene Epigenetics Epigenetics can be defined in various ways, depending ... proteins that interact with the C-terminus Results from the screen indicated that chromatin -regulating proteins interact with the LHX3 C-terminus However, a general understanding of epigenetics...
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Báo cáo khoa học:

Báo cáo khoa học: "Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus" pdf

... as: Ang et al.: Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus Virology Journal 2010 7:24 Submit ... essential for mediating the infectious entry process of DENV into cells siRNA profiling of human membrane trafficking genes required for DENV infection An array of 119 siRNA pools targeting genes known ... strongly indicate a key role for clathrin function in the entry of DENV into cells In consistent with involvement of clathrin in mediating DENV entry into human hepatocyte cell line in this study,...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production

The Role of Genetically Modified Organisms (GMOs) in Beverage Production

... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes in ... Finally, the food and beverage industries hope that the next generation of GM products will deliver compelling consumer beneÞts THE FUTURE OF GENETICALLY MODIFIED FOODS The next generation of ... of relevance to the beverage industry will be provided HISTORY OF GENETIC MODIFICATION OF FOOD PLANTS AND ANIMALS People have been genetically modifying the food supply during the thousands of...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... confirmed by Lin-54 binding to the CHR, cooperating with E2F4 binding to the CDE in EMSAs in vitro [86] ChIP experiments on the Cdc2 gene also provided insights into the association of other cell cycle ... proteins with the promoter E2F4 binding during the cell cycle coincides with the binding of p107 or p130 [61,85] Another E2F site distal to the E2F ⁄ CDE acts as an activating element binding ... responsible for cell cycle-dependent expression of the gene Surprisingly, deregulation of the promoter does not lead to loss of its activity but causes activation in resting cells and in G1 cells Therefore,...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx

Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx

... activation of the glutaminase reaction and CTP synthesis was compared (Fig 5) In the absence of GTP, the rate of glutamine hydrolysis was signicantly higher than the rate of CTP synthesis so that the reactions ... (min) Fig Isothermal titration calorimetry of the glutaminase activity of L lactis CTP synthase (A) Enthalpogram showing the recording of steady-state rates for the hydrolysis of glutamine at increasing ... of the glutaminase reaction of CTP synthase from L lactis in order to distinguish between the effects of GTP on the glutaminase reaction and the CTP synthesis reaction The results from this work...
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Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc

Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc

... core tyrosinase domain [1] One proposed function of the C-terminal extension in plant and fungal polyphenol oxidases is a role in membrane binding, making them similar to the mammalian tyrosinases, ... three domains: a twin arginine translocase (TAT) signal peptide, a core domain containing the two copper-binding motifs and a C-terminal extension (Fig 1B) The presence of a predicted TAT signal peptide ... pro -tyrosinase, trypsinized pro -tyrosinase or recombinant core tyrosinase significantly increases the overall stability of the protein It was also apparent that the C-terminal extension of pro -tyrosinase reduces...
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The Role of Small and Large Businesses in Economic Development doc

The Role of Small and Large Businesses in Economic Development doc

... innovation Small firms are the great innovators in some industries, while large firms are the great innovators in others Moreover, small and large businesses interact in innovative activity The ... businesses There is no clear evidence that small businesses are more effective innovators Further, the innovations of both small businesses and large businesses are inextricably linked Still, small ... analysis evaluated the economic development role of small businesses vis-à-vis large businesses It suggests that small businesses may not be quite the fountainhead of job creation they are purported...
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Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx

Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx

... helix of the third cluster of CHCs is part of the inter-domain segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation of the ... rather than functional role Role of hydrophobic contacts in serine hydroxymethyltransferase In the present study, the importance of the third hydrophobic cluster as a structural determinant of ... Y55¢ interacts with the phosphate moiety of PLP; E57¢ is crucial in the binding of the l -serine hydroxyl group [15] and in the catalysis of the hydroxymethyltransferase reaction [16]; and Y65¢ interacts...
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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

... raise the possibility that GSK3 may help to coordinate increases in glucose uptake and glycogen synthesis allowing for more effective ÔchannellingÕ of glucose into glycogen in response to insulin ... Effects of insulin, Li and SB-415286 on signalling elements implicated in the regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their ... by insulin Regulation of GS activity To establish the importance of GSK3 inhibition on GS activity we monitored the effects of insulin, Li, SB-415286 and wortmannin (a PI3K inhibitor) on the incorporation...
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The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

... when they did not understand the meaning of the questions in this section Each session took 30 including instructions at the beginning, the listening comprehension task, and completion of the ... placement in the IEP was determined on the basis of an in- house placement test of listening, reading, and writing skills (reliability coefficients for the listening and reading sections of this ... saw in the lecture, discussion of the results begins with a description of these gestures, their relative frequency, and examples, followed by the results of the listening comprehension task and...
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Báo cáo khoa học: The role of the Fe-S cluster in the sensory domain of nitrogenase transcriptional activator VnfA from Azotobacter vinelandii potx

Báo cáo khoa học: The role of the Fe-S cluster in the sensory domain of nitrogenase transcriptional activator VnfA from Azotobacter vinelandii potx

... upstream of the GAF domain are the potential ligands of the Fe-S cluster Consequently, the binding of the ATP analog and the subsequent rearrangement of the interdomain interaction affects the electronic ... with the reconstitution of Fe-S clusters in aerobically purified apo -VnfA support the presence of [Fe3S4]+ in VnfA To obtain further evidence demonstrating the involvement of the Fe-S cluster in in ... Strep -VnfA indicate that the N-terminal cysteine residues are plausible candidates for the ligands of the Fe-S cluster Thus, the locus of the Fe-S cluster should be in the N-terminal GAF domain...
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