role of antioxidants and oxidative stress in cardiovascular diseases
Báo cáo khoa học: Calcium, mitochondria and oxidative stress in neuronal pathology Novel aspects of an enduring theme pdf
Ngày tải lên :
07/03/2014, 12:20
... imposing a continuous load of
calcium to the neuron. The turning point upon which
the cell looses the ability to buffer the incoming calcium
resulting in an abrupt, sustained and irreversible
increase ... by proteins resi-
ding in both the inner and outer mitochondrial
membrane, that is activated by mitochondrial Ca
2+
overloading and other factors including oxidative stress
[88,89]. In neurons ... for a role of Trp proteins in the oxidative
stress- induced membrane conductances of porcine
aortic endothelial cells. Cardiovasc Res 42, 543–
549.
236 Wehage E, Eisfeld J, Heiner I, Jungling E,...
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báo cáo hóa học: " Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis" pptx
Ngày tải lên :
19/06/2014, 22:20
... implicating both oxidative
stress and inflammatory mechanisms in AD pathogenesis.
Effect of indomethacin plus vitamin E supplementation on sol-uble Aβ levelsFigure 3
Effect of indomethacin plus ... a subset of NSAIDs
(e.g. ibuprofen, flurbiprofen, indomethacin) reduced
brain inflammation and Aβ levels in addition to the dep-
osition of Aβ in brain [13,14]. Despite this evidence, and
the ... that a full dose of
indomethacin alone despite a significant reduction in
brain inflammation had only a marginal effect on brain
oxidative stress in the Tg2576 mice [16]. This finding sug-
gests...
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Báo cáo y học: "Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor" potx
Ngày tải lên :
09/08/2014, 01:23
... CD40 ligand, interleukin 1, or interleukin 6 [10]. Oxi-
dative stress also promotes angiogenesis [13]. The link
between oxidative stress and angiogenesis is emphasised
in SSc by the baseline correlation ... injury, oxidative stress, and impaired
angiogenesis are prominent features of systemic sclerosis
(SSc). We compared serum markers of these phenomena at
baseline and after treatment with nifedipine in ... have
acute and sustained beneficial effects on oxidative markers
of damage in SSc patients [17].
The aim of our study was, first, to investigate serum
endothelial cell markers of adhesion (sVCAM-1) and...
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Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
Ngày tải lên :
26/10/2012, 09:07
... synthase. The increased
activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased
and effective recycling of citrulline to arginine in anoxia, making nitric ... findings of NO involvement in pathophysiol-
ogy of hypobaric hypoxia in brain (42-43). In this
study the increased activity of NOS in anoxia may
represent predominantly the nNOS form. In inflam-
matory ... reperfusion damage in brain.
The increased activities of AS and AL indicate the
effective recycling of citrulline to arginine and suggest
a functional role to citrulline –NO cycle enzymes in
anoxia....
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The Role of Small and Large Businesses in Economic Development doc
Ngày tải lên :
06/03/2014, 19:20
... growth from the second quarter of 2000 into job
classes using beginning size of firm, mean size of firm over the period,
and end size of firm. If the beginning size of the firm is used to classify
firms, ...
enterprises with tax breaks, financial incentives, and other induce-
ments. Instead, they are relying on building businesses from the ground
up and supporting the growth of existing enterprises. This ... efficient at innovation. Small firms
are the great innovators in some industries, while large firms are the
great innovators in others. Moreover, small and large businesses interact
in innovative...
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The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx
Ngày tải lên :
10/03/2014, 05:20
... & Lynch, K. (1999).Offeringa
hand to pragmatic understanding: The role of speech and gesture in
comprehension and memory. Journal of Memory and Language, 40,
577–592.
Lansing, C. R., & McConkie, ... area of an image for speech information. Following a speech-
reading experiment using eye-tracking equipment with native
speakers of English, Lansing and McConkie (1999) suggested
that in terms of ... pottery and involved description and gesture use.
Materials recording and editing. Two video-recording ses-
sions using the same lecture outline were scheduled, each last-
ing approximately 20 min....
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Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx
Ngày tải lên :
15/03/2014, 10:20
... value to existing infrastructure.
Data and evidence on the role
of savings and retail banks in
access to finance
WSBI has conducted research into the role of savings
banks in providing access ... use of their front and back of ce
systems for disbursing of loans and collecting
loan repayments.
Another promising track for savings
banks is to invest their savings deposits in
microfinance ...
microfinance institutions by specialising
in wholesale lending to microfinance
institutions for lending to their micro
borrowers. Savings banks could refinance
well-functioning microfinance institutions...
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Báo cáo y học: " Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilag" pps
Ngày tải lên :
09/08/2014, 14:21
... 2',7'-
dichlorodihydrofluorescein diacetate.
Results Basal and IL-1β-induced 2-DG uptake, including the
affinity (1.066 ± 0.284 and 1.49 ± 0.59 mM) and maximal
velocity (0.27 ± 0.08 and 0.33 ± 0.08 nmol/μg protein/hour),
and ... Differential
roles of hydrogen peroxide and superoxide in mediating IL-1-
induced NF-κB activation and iNOS expression in bovine artic-
ular chondrocytes. J Cell Biochem 2003, 88:783-793.
22. Henrotin ... found in the
GLUT-1 protein content in normal and OA chondrocytes cul-
tured in mannitol-supplemented medium relative to their
respective control cells maintained in RGM (data not shown).
Role of...
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Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
Ngày tải lên :
06/03/2014, 19:20
... significant insights into the roles and mechan-
isms of PM
2.5
-associated physiology and pathology.
In summary, our data demonstrate the important
effects of PM
2.5
exposure on oxidative stress and ... effect
of ambient PM
2.5
onWATandBATspecificgenesin
different adipose depots. There are several major find-
ings in this study. First, exposure to PM
2.5
resulted in
oxidative stress in BAT. ... blot.A.RepresentativebandsofFAandPM
2.5
on
UCP1 protein level in iBAT by Western blotting. B. Quantitative results of Western blotting of UCP1. n = 8. *P<0.05 vs. FA.
Xu et al. Particle and Fibre Toxicology...
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Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
Ngày tải lên :
22/03/2014, 16:20
... College, Beijing, China
2 Key Laboratory of Human Diseases Animal Model, State Administration of Traditional Chinese Medicine, Institute of Laboratory Animal
Science, Chinese Academy of Medical ... A rapid and sensitive method for
the quantitation of microgram quantities of protein
utilizing the principle of protein-dye binding. Anal
Biochem 72, 248–254.
CYP2E1 causes apoptosis of cardiomyocytes ... overexpression of CYP2E1 both in vivo
and in vitro is associated with several cellular markers
of oxidative stress, including products of lipid peroxi-
dation (e.g. 4-hydroxynonenal and malondialdehyde),
as...
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Báo cáo khoa học: "Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells" pptx
Ngày tải lên :
07/08/2014, 17:22
... C, Becker S.
Cytotoxicity and induction of
proinflammatory cytokines from human monocytes exposed
to fine(PM
2.5
) and coarse particles(PM
10
-
2.5
) in outdoor and
indoor air. Toxicol Appl Pharmacol ... PM10
suggesting that PM2.5 induced more oxidative stress than
PM10. In the single strand breakage assay using pBR322
DNA, the ratio of changed form II/total plasmid DNA (form
F
ig. 10. RT-PCR analysis of ... 11–18
Comparative study of PM2.5 - and PM10 - induced oxidative stress
in rat lung epithelial cells
Jin-Hyuk Choi, Jun-Sung Kim, Young-Chul Kim
1
, Yoon-Shin Kim
2
, Nam-Hyun Chung
3
and
Myung-Haing Cho*
Laboratory...
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Báo cáo lâm nghiệp: "Response to an ozone gradient of growth and enzymes implicated in tolerance to oxidative stress in Acer saccharum (Marsh.) seedlings" pot
Ngày tải lên :
08/08/2014, 00:22
... flush, consisting of preformed leaves and
the second flush as neoformed flush consisting of neoformed leaves
as described by Gregory [18].
2.1.2. Harvesting of seedlings
Seedlings were randomly harvested ... tubes for 5 min in boiling water. The colorimetric determination
of NO
2
−
was done by mixing 0.25 mL of incubation medium with
0.25 mL 0.02% N-(1-Naphtyl) ethylenediamine and 0.25 mL of sul-
fanilamide. ... processes.
However, after 85 days, the NR activity in the seedlings was
lower and decreased with increasing O
3
. At that time in the
season and with increasing oxidative stress, NH
3
may have
been provided...
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Báo cáo y học: "Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function" pptx
Ngày tải lên :
09/08/2014, 06:22
... Our findings
clearly show the presence of oxidative stress in degenerat-
ing cartilage, and the resultant telomere erosion and dys-
function of chondrocytes in vitro and in vivo, suggesting a
role ... provides insight into the involvement of oxidative
stress in the pathogenesis of OA from the viewpoint of oxi-
dative stress induced genomic instability, especially tel-
omere erosion, and chondrocyte ... A: Detection of nitro-
tyrosine in aging and osteoarthritic cartilage: Correlation of
oxidative damage with the presence of interleukin-1beta and
with chondrocyte resistance to insulin-like growth...
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