... subfamily of protein- ases also belonging to the metzincins (zinc-bearing pro- teinases) and structurally related to MMPs: the ADAMs (A Disintegrin And Metalloproteinase) [10-14]. ADAM pro- teinases ... complex than that of MMPs. Domains shared with MMPs are the prodomain maintaining the catalytic site inactive and the metallopro- teinase domain containing the Zinc binding site. ADAM activation mechanisms ... metalloproteinase domain with its catalytic consensus site is active in only about half of ADAM pro- teinases. The following domains are characteristic of ADAMs and include a disintegrin domain mediating
Ngày tải lên: 12/08/2014, 14:20
... P1 In conclusion, maternal SE increased markers of hypoxia and oxidative stress with mitochondrial dysfunction and cell damage in both dams and offspring, and upregulated inflammatory markers in ... during gestation can cause lifelong adverse effects in the offspring’s brain Several factors may contribute including inflammation, oxidative stress and hypoxia, whose changes in the developing ... Smoking and second hand smoking in pregnant women may result in placental transfer of toxic agents present in cigarettes and transmit a risk to the developing fetal brain In addition there are increased
Ngày tải lên: 04/12/2022, 14:50
Báo cáo y học: " Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivators" pdf
... increase radical generation and thereby circumvent the difficulty in inducing oxidative stress by solely increasing pO 2 [49]. Menadione and para- quot are most frequently used to increase intracellular ... Regulation of HIV-1 transcription... Howley PM: Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity ... terminated. Our results, and those of others, indicate that oxidizing conditions increase the expression of a TAR-dependent reporter in the presence of Tat [24]. In addition, our results indicate
Ngày tải lên: 12/08/2014, 04:20
Báo cáo khoa học: " The role of NH4Cl and cysteine proteases in Human Papillomavirus type 16 infection" ppsx
... cathepsin B or cathepsin L protease, Figure Cathepsin B and L treatment of HPV16 increases binding Cathepsin B and L treatment of HPV16 increases binding Reporter virus binding was compared in 293 ... L enhanced infectivity by cleaving and removing a highly glycosylated mucin domain in the Ebolavirus glycoprotein and resulted in increased binding suggesting that cathepsins are indeed present ... protease treatment of HPV16 for hour can increase binding, that longer time incubation results in a loss of total binding, and that the increase in infection after protease treatment of reportervirions
Ngày tải lên: 12/08/2014, 04:21
The Position and role of small and medium enterprises in a national economy – the case of Japan
... Structure ,the Ministry of Health, Labour and Welfare Notes: 1) The wages of an enterprise with a thousand persons and over is set as 100 2) The wage of a male in the manufacturing industry is indicated ... have been declining since then In the latter half of the 1960’s, a comparatively remarkable increase in the number of SMEs with a capital scale of 1-5 million yen becomes apparent, and from the ... equivalent to 87% of the increase number of employees in overall industries in the ten years from 1980 about 18.6 million people Moreover, in Europe, the number of small business has increased after
Ngày tải lên: 01/11/2014, 22:05
Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis 3
... 2) initiated our interest in the role of NK cells in the development of nasal polyps and chronic sinusitis The aim of our study is to investigate the involvement of NK cells in the chronic inflammation ... varieties of cytokines and chemokines In addition to its well known role in INF-γ and TNF-α production in viral infections, it can also secrete IL-5 which may contribute to eosinophil inflammation.3 ... Chapter Role of Natural Killer Cell in the Pathogenesis of Nasal Polyps and Chronic Sinusitis 3.1 Biology of Natural Killer Cells 3.1.1 Lymphocytes in Innate and Adaptive Immunity Both specific and
Ngày tải lên: 16/09/2015, 17:13
Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis 2
... dyskinesia,8,9 and other underlying diseases. Although many theories have been suggested, the roles of allergy and infection remain the most important and controversial underlying mechanisms in ... complex inflammation characterized by infiltration and activation of various types of inflammatory cells. In this study, it is proposed that: I. The cell pattern and role of inflammatory cells in ... difference of eosinophils should be taken into consideration.100 In addition, the infiltration of eosinophils in nasal polyp tissue and inflamed sinus mucosa may be under the control of chemical
Ngày tải lên: 16/09/2015, 17:13
Role of allergy and mucosal inflammation in nasal polyps and chronic sinusitis
... ROLE OF ALLERGY AND MUCOSAL INFLAMMATION IN NASAL POLYPS AND CHRONIC SINUSITIS HAO JING NATIONAL UNIVERSITY OF SINGAPORE 2004 ROLE OF ALLERGY AND MUCOSAL INFLAMMATION IN NASAL POLYPS AND ... The involvement of Trichophyton rubrum in the pathogenesis of nasal polyps and chronic sinusitis 5.1 Role of fungi in the pathogenesis of nasal polyps and chronic sinusitis 5.1.1 Incidence of ... cell scores in nasal polyps and its paired middle turbinate, and middle turbinate of allergic rhinitis patients and controls 2.5.2 Inflammatory cell scores in inflamed sinus mucosa and its paired
Ngày tải lên: 16/09/2015, 17:14
The role of credit and monetary transmission in vietnam a var approach luận văn thạc sĩ
... • INSTITUTE OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS UNIVERSITY OF ECONOMICS HO CHI MINH CITY VIETNAM VIETNAM- NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS THE ROLE OF CREDIT AND ... RELEVANCE AND BACKGROUND OF STUDY The restructuring of state owned commercial banks (SOCBs) and the establishment of join stock banks (JSBs), had appeared since Vietnam financial reform in the first ... important role of financial intermediaries and credit markets Modigliani and Papademos (1977) also admitted that the traditional theory of monetary mechanism ignored the functions of financial intermediaries
Ngày tải lên: 13/08/2017, 10:22
The role of credit and monetary transmission in vietnam a VAR approach
... the similarity and difference among them to indentify the thesis’s contribution Our finding confirms the existing of credit channel and its role in Vietnam case since Bernanle and Gertler (1995) ... RELEVANCE AND BACKGROUND OF STUDY The restructuring of state owned commercial banks (SOCBs) and the establishment of join stock banks (JSBs), had appeared since Vietnam financial reform in the first ... important role of financial intermediaries and credit markets Modigliani and Papademos (1977) also admitted that the traditional theory of monetary mechanism ignored the functions of financial intermediaries
Ngày tải lên: 07/12/2018, 23:41
The role of growth and income distribution in poverty reduction the case of the south eastern asian countries
... ESTIMATION OF GROWTH ELASTICITY OF POVERTY 68 55 Country Year Type Indonesia 1987 Indonesia Mean Gini Headcount Poverty Gap Squared Gap Initial Income Initial Gini Coefficient Ratio Index Index ... growth elasticity of poverty in absolute value Finally, the impacts of income growth and inequality are larger on the more sensitive measures of poverty viii TABLES OF CONTENTS LIST OF TABLES ... University of Economics Erasmus University of Rotterdam, Ho Chi Minh City, Vietnam The Netherlands VIETNAM – THE NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONMICS THE ROLE OF GROWTH AND INCOME
Ngày tải lên: 03/01/2019, 00:07
An investigation of the mediating role of personality and family functioning in the association between attachment styles and eating disorder status
... reaction, which in turn may influence ED pathology [13] Against the background of our findings, introversion and deficits in family functioning could be understood as involving a lack of resources ... personality and EDs are the results from studies investigating family functioning in the context of EDs [33] Family functioning is defined by the interaction of family members involving physical, ... family functioning and EDs, as well as examining the mediating role of personality and family functioning in the association between attachment and EDs H1: We hypothesize that an insecure attachment
Ngày tải lên: 10/01/2020, 13:12
The mediating role of technology and logistic integration in the relationship between supply chain capability and supply chain operational performance
... exporting, tin to China, Malaysia, UK, Singapore, and other highly industrialized countries The supply chain of the tin industry is one of the subjects of greatest interest The operations of tin industry ... shared planning and sharing of information The effectiveness of supply chain management is entirely based on its capability of reducing cost, enhancing production flexibility, bringing innovation, ... the definitions of the SCOR model is more to return on investment In this study, supply chain reliability is defined as the quality of the supply chain in performing and maintaining the perfect
Ngày tải lên: 27/05/2020, 03:25
The role of instrumentation and control systems in power uprating projects for nuclear power plants ( TQL)
... allowed relaxation in certain operating limits while still maintaining the existing operating margins The principal operating limits affected were: — Channel power limit redefined (increased from ... activities in nuclear power plant operating performance and life cycle management are aimed at increasing Member State capabilities in utilizing good engineering and management practices developed and ... licence renewal, and the modernization of instrumentation and control (I&C) systems of NPPs in Member States The subject of the I&C systems’ role in power uprating projects in NPPs was suggested
Ngày tải lên: 07/07/2020, 13:30
Dr sridhar role of CT and CT perfusion in evaluation of stro
... Hrs Goals of Acute Stroke Imaging • Parenchyma: Assess early signs of acute stroke and rule out hemorrhage • Pipes: Assess extracranial and intracranial circulation for evidence of intravascular ... estimated to be 2.21* *Neurology Asia 2006; 11 : – “Time is Brain” “Time is Brain” National Institute of Neurological Diseases and Stroke trial (NINDS) 3Hrs (N Engl J Med 1995;333:1581-7.) European Cooperative ... Role of CT in Acute Stroke Dr PG Sridhar Sr Consultant Epidemiology • Third most common cause of death world wide • Age adjusted prevalence rate of stroke in India 250350/100,000*
Ngày tải lên: 13/08/2020, 09:27
The Role of Credit and Monetary Transmission in Vietnam: A Var Approach : Luận văn thạc sĩ
... • INSTITUTE OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS UNIVERSITY OF ECONOMICS HO CHI MINH CITY VIETNAM VIETNAM- NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS THE ROLE OF CREDIT AND ... RELEVANCE AND BACKGROUND OF STUDY The restructuring of state owned commercial banks (SOCBs) and the establishment of join stock banks (JSBs), had appeared since Vietnam financial reform in the first ... important role of financial intermediaries and credit markets Modigliani and Papademos (1977) also admitted that the traditional theory of monetary mechanism ignored the functions of financial intermediaries
Ngày tải lên: 01/09/2020, 15:06
The role of credit and monetary transmission in Vietnam: a VAR approach
... the similarity and difference among them to indentify the thesis’s contribution Our finding confirms the existing of credit channel and its role in Vietnam case since Bernanle and Gertler (1995) ... RELEVANCE AND BACKGROUND OF STUDY The restructuring of state owned commercial banks (SOCBs) and the establishment of join stock banks (JSBs), had appeared since Vietnam financial reform in the first ... important role of financial intermediaries and credit markets Modigliani and Papademos (1977) also admitted that the traditional theory of monetary mechanism ignored the functions of financial intermediaries
Ngày tải lên: 01/09/2020, 16:13
The role of credit and monetary transmission in vietnam, a var approach , luận văn thạc sĩ
... the similarity and difference among them to indentify the thesis's contribution Our finding confirms the existing of credit channel and its role in Vietnam case since Bemanle and Gertler (1995) ... important role of financial intermediaries and credit markets Modigliani and Papademos (1977) also admitted that the traditional theory of monetary mechanism ignored the functions of financial intermediaries ... to decisions of policy makers Hence, understanding the position of credit channel in financial market is crucial to policy makers In detail, understanding the transmitted mechanism of monetary
Ngày tải lên: 16/09/2020, 20:13
The role of credit and monetary transmission in vietnam, a VAR approach
... UNIVERSITY OF ECONOMICS HO CHI MINH CITY VIETNAM INSTITUTE OF SOCIAL STUDIES THE HAGUE THE NETHERLANDS VIETNAM - NETHERLANDS PROGRAMME FOR M.A IN DEVELOPMENT ECONOMICS THE ROLE OF CREDIT AND MONETARY ... RELEVANCE AND BACKGROUND OF STUDY The restructuring of state owned commercial banks (SOCBs) and the establishment of join stock banks (JSBs), had appeared since Vietnam financial reform in the first ... evidence the insignificant role of credit in transmission of monetary policy In general, despite of different market conditions and Vietnam’s specific characteristic, the empirical finding still
Ngày tải lên: 16/09/2020, 20:13