Development of NMR methods for the structural elucidation of large proteins

... DEVELOPMENT OF NMR METHODS FOR THE STRUCTURAL ELUCIDATION OF LARGE PROTEINS ZHENG YU (B.Sc., Xiamen University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF BIOLOGICAL ... analysis of complex, x    Development of NMR methods for the structural elucidation of large proteins Summary   crowded and folded high-dime...

Ngày tải lên: 11/09/2015, 09:57

... number of spins By linearity of the Fourier transform the direct relation between the peak integral and the number of spins of the corresponding chemical group holds for the spectrum of superposed ... derivation due to the time-dependence of the unit vectors Using the product rule for the derivation and the fact that the time derivative of the u...

Ngày tải lên: 29/05/2014, 18:32

... determination is the spectral assignment procedure This involves sequence-specific resonance assignment of NMR signals and the assignment of NOESY spectra Resonance assignment forms the basis for characterizing ... obtain the assignments of the Cα and CO of the same residue Then, the CO frequency is used to obtain assignments for the HN and 15N of...

Ngày tải lên: 04/10/2015, 15:52

... evaluation of the performance of a classification algorithm The SN is the proportion of correct positive classifications out of the number of true positives The SP is the proportion of correct ... classifications out of the number of true negatives The accuracy is the total number of correct classifications out of the total number of samples The PPV...

Ngày tải lên: 14/08/2014, 17:22

... 25 25 25 Time (h) 2.0 5.0 6.0 1.5 5.0 2.0 Yield %b (1 03:10 4) (E/Z)c 25 (1 00: 0) (8 0/2 0) 23 (1 00: 0) (8 0/2 0) 25 (7 6:2 4) (8 0/2 0) 45 (1 00: 0) (8 0/2 0) 49 (1 00: 0) (8 0/2 0) 69 (1 00: 0) (8 0/2 0) 105 105a 105b ... Yield 9a (% ) ( : ) (E/Z) 15 (7 5:2 5) (1 00/ 0) 22 (2 3:7 7)...

Ngày tải lên: 16/09/2015, 17:11

... an effort to develop an effective extraction method for bioflocculants from the microbial cell surface Materials and Methods Activated sludge samples Activated sludge samples were collected from ... was the most effective extraction method for activated sludge However, cell disruption is not effective for the isolation of bioflocculants Thus, NaOH extr...

Ngày tải lên: 05/09/2013, 09:08

... qualitative evaluation of lexical association measures, mainly for the following reasons: the instability of precision values obtained from the rst few percent of the data in the SLs; the lack of signicant ... precision values above 50% for the rst 10% of the list, but is outperformed by the t-test afterwards Looking at the rst 40% of the data, th...

Ngày tải lên: 20/02/2014, 18:20

... is found, all of them can be picked up Then the father must stack up to De evidence for same future proposition level is open for further expansion To determine the appropriateness of this algorithm ... the top of the tree, for are evidence Consider L to De a the tree, representing the lowest that can receive more evidence to dummy) For every node NEN on the the fo...

Ngày tải lên: 17/03/2014, 19:21

... University of California [5,6] provided a tremendous resource of knowledge related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental ... factors limiting the advancement of the study of human movement is the measurement of skeletal movement from markers or sensors placed on th...

Ngày tải lên: 19/06/2014, 10:20

... with the Vietnamese research Institutes involved Success Alliance is also thanked for their assistance in providing information regarding the cocoa industry in Vietnam and in the establishment of ... darken in colour during drying as the majority of browning reactions will occur during this process DRYING OF COCOA Drying of cocoa is an important step in co...

Ngày tải lên: 21/06/2014, 06:20

... for some functional equations in a single variable We prove the generalized Ulam-Hyers stability of the single variable equation w◦f ◦η f h 1.8 As an application of our result for 1.8 , the stability ... the stability of monomial functional equations, ” Fixed Point a Theory, vol 8, no 2, pp 201–218, 2007 25 V Radu, The fixed point alternative a...

Ngày tải lên: 22/06/2014, 06:20

... American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Organism Water boatman Water dog Water fern Water hyacinth Watermeal Water ... American Water Works Association, Water Environment Federation Standard Methods for the Examination of Water and Wastewater Algae General...

Ngày tải lên: 29/07/2014, 18:58

... Standard Methods for the Examination of Water and Wastewater Synedra © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard ... the Examination of Water and Wastewater Pandorina © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environm...

Ngày tải lên: 29/07/2014, 18:58