Characterisation of lung dendritic cell function in a mouse model of influenza
Characterisation of lung dendritic cell function in a mouse model of influenza
... resulting in intracellular ionic imbalance and activation of the inflammasome (Ichinohe et al 2010) Although influenza infection results in activation of the inflammasome in both lung stromal and ... ciliated epithelium results in initial shrinkage and vacuolaization of the cells, culminating in necrosis and eventual desquamation of these cells into the luminal space The lung interstitium may ... discrimination mechanism is particularly important given that host RNA are abundant within the cytosol Upon RIG-I binding to influenza vRNA, the CARD domains initiate a signalling cascade by associating with...
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Báo cáo y học: " GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma" ppt
... (s.e.m.) After log transformation, airway responsiveness to methacholine was statistically analyzed by a general linear model of repeated measurements (ANOVA) followed by a post hoc comparison ... characterized by AHR, induction of specific IgE and airway eosinophilia We show for the first time that AHR is dramatically increased by GITR triggering at the time of allergen challenge, resulting in a ... Respiratory Research 2009, 10:93 Background Allergic asthma is an inflammatory disease characterized by reversible airway obstruction, and is associated with airways hyperresponsiveness (AHR)...
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The role of interferon gamma in regulating antigen specific CD8 t cell responses in a mouse model of influenza
... with both the avian and human strains of influenza This facilitates viral reassortment and the generation of novel 10 Chapter 1: Introduction human viral strains with the potential of transferring ... cells HAspecific antibodies form a solid correlate of protection against influenza provided that they match the virus causing the infection In contrast to the antibodies targeted to the HA head region, ... immunity takes days to be initiated and then for the response to peak In the interim, it is the innate immune response that combats viral replication in the initial phase of the infection, buying...
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Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka N, Itoh K, Harada M, Todo S: Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil ... cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage ... vaccination with mGC8 cells and GM-CSF T cells generated from TVDLN at day nine after vaccination were polyclonally activated and expanded as described in the Methods section and tested for tumorspecific...
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Báo cáo y học: " Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease" potx
... Homma Y, Kawakami Y: Enhancement of goblet cell hyperplasia and airway hyperresponsiveness by salbutamol in a rat model of atopic asthma Thorax 2001, 56:19-24 30 Tamaoki J, Tagaya E, Kawatani ... Efficacy of inhaled corticosteroids in asthma The Journal of allergy and clinical immunology 1998, 102:531-538 29 Kamachi A, Munakata M, Nasuhara Y, Nishimura M, Ohtsuka Y, Amishima M, Takahashi ... this article as: Riesenfeld et al.: Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease Respiratory Research 2010 11:22 Page 11 of 11...
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Báo cáo y học: " Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma" potx
... et al.: Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma Respiratory Research 2010 11:138 Submit your next manuscript ... function and airway inflammation caused by a potent oxidant like Cl2 is relatively under-investigated Recently a combination of anti-oxidants (ascorbic acid, desferroxamine and N-acetylcysteine) was ... after a single high acute inhalation of chlorine in rats Eur Respir J 1998, 11:922 Koohsari H, Tamaoka M, Campbell HR, Martin JG: The role of gamma delta T cells in airway epithelial injury and...
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Báo cáo y học: " Role of pulmonary intravascular macrophages in endotoxin-induced lung inflammation and mortality in a rat model" pot
... delineated role of PIMs by comparing LPS-induced lung inflammation and mortality in BDL rats and GCtreated BDL rats The dramatic finding was 100% and 80% survival in BDL rats that were treated with ... AC: Quantitation of eosinophil and neutrophil infiltration into rat lung by specific assays for eosinophil peroxidase and myeloperoxidase Application in a Brown Norway rat model of allergic pulmonary ... BDL rats, which recruit PIMs and have been used by others as a model of hepato -pulmonary syndrome, to investigate the role of PIMs in endotoxin-induced mortality and lung inflammation The data...
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Báo cáo y học: " Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma" doc
... peptides including LANP, VD and KP in modulating lung inflammation In this report we show that overexpression of VD attenuates airway inflammation in a mouse model of allergic asthma The effects of ... determine airway resistance values and peak values obtained after each MeCh challenge were plotted [16] Modulation of lung inflammation by VD To test the effects of VD on airway inflammation, a separate ... down-regulated NPRA expression We have reported that NPRA plays a role in airway inflammation Knockout of NPRA in mice resulted in less lung inflammation [11] Inhibition of NPRA by small inferfering...
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Báo cáo y học: "Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds)" pot
... data confirmed that Wlds reactivates dormant cell cycle pathways, pushing cells toward cell cycle re-entry rather than inhibiting it Role of Pttg1, NAD, and VCP pathways in mediating cell cycle ... SuperArray analysis as being upregulated by more than twofold The final portion of the graph shows similar increases in cell cycle proteins not included on the SuperArray plate, showing that increased ... Sameshima M, Matsuda Y, Kaneda S, Nagai Y, Yamao F, Seno T: Abnormal integrity of the nucleolus associated with cell cycle arrest owing to the temperature-sensitive ubiquitin-activating enzyme...
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Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf
... [7], although kinetic studies [8] indicate that its alanineglyoxylate aminotransferase activity is not favored over aminobutyrate-pyruvate, b-alanine-pyruvate and dimethylarginine-pyruvate aminotransferase ... (p97) cofactor (p47) Aminoacylase Phosphoglycerate mutase Indolethylamine N-methyltransferase Peroxiredoxin Apolipoprotein A- I Abhydrolase domain containing 14b D-Amino Protein name ApoA4 ActB ... version 5.0 software (GeneBio, Geneva, Switzerland), including spot detection, quantification, normalization, data analysis and statistics Comparative analysis of protein spots was performed by matching...
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Báo cáo khoa học: " Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model" docx
... survival data we also analyzed the animals' clinical status We found that imatinib treatment in both early and late treatment arms also attenuated radiationrelated clinical adverse effects such as ... imatinib treatment starting days and weeks after radiation (RT) Fibrosis is characterized by diffuse bilateral areas of "ground-glass" attenuation and intralobular reticular opacities (b) Quantitative ... Importantly to us, imatinib treatment starting weeks Figure (a) Kaplan-Meier analysis of mouse survival following thoracic irradiation and imatinib treatment (a) Kaplan-Meier analysis of mouse...
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Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance docx
... of adenomatous polyposis coli (APC), somatostatin, carbonic anhydrase and tenascin C in the cerebellum (Figure 1a) and those of lysyl oxidase, carbonic anhydrase 4, enolase 3β and creatine kinase ... sensitive to thyroid hormone and the primary mode of T3 action is a direct influence on cardiac gene expression [20] Increased heart rate (tachycardia) and myocardial contractility are clinical features ... selection and data analysis All array data were deposited in the NCI-CIT microarray database [65] where Cy3 and Cy5 signals were median normalized and expression ratios (Cy5/Cy3) were calculated The...
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Báo cáo y học: " Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa" docx
... microarray analysis Additional data file is a table listing highly ranked retinal miR target genes predicted using miRanda The miRNA array data are available at Array Express [58] using accession ... version of this paper Additional data file is a table listing retinal miR expression data from Exiqon microarray analysis Additional data file is a table listing retinal miR expression data from Ambion ... rett-testmedian expressionandhighlyin triplicate P 129, and miRanda month; analysis 1analysis are Exiqon c57, values analysis Log are using miRanda Student's t-test microarrayby P at predicted of retinal...
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Báo cáo y học: "Diarrhea as a cause of mortality in a mouse model of infectious colitis" ppt
... anhydrases CA I and CA IV and aquaporins Aqp4 and Aqp8 [78-80] These results indicate that infectious diarrhea and noninfectious inflammationassociated diarrhea may have common mechanisms of pathogenesis ... adult mouse gastrointestinal tract identified by microarray analysis Gastroenterology 2002, 122:1467-1482 Bekku S, Mochizuki H, Takayama E, Shinomiya N, Fukamachi H, Ichinose M, Tadakuma T, Yamamoto ... significant Abbreviations A/ E, attaching and effacing; AP, activator protein; AQP, aquaporin; CA, carbonic anhydrase; CFTR, cystic fibrosis transmembrane conductance regulator; dChip, DNA-Chip Analyzer;...
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Từ khóa: control of adult stem cell function in bioengineered artificial niches matthias p lutolf and helen m blaucounta function in a similar way to return the number of columns in the table nếu không bạn có thể dùng counta chức năng trong một cách tương tự để trở về số lượng các cột trong bảngselect a range of cells or make sure that the active cell is in a table or pivottable reportresponsibilities of data link layer in a osi modelimplementing the power function in a procedurean essential function in a democratic societyfunction in a templateexperience with op 1 in a rabbit model of lumbar fusionsunit function in a dirichlet boxinvoking a function in a conditional expression1β gene expression and vasogenic edema development in a porcine model of intracerebral hemorrhage pdfinnate and acquired immunity and epithelial cell function in chronic rhinosinusitistnfα monoclonal antibodies combinatorial treatment inhibits autoimmune disease in a murine model of systemic lupus erythematosusin vivo germ line stem cell migration a mouse modelmice are susceptible to increased lung inflammatory cell influx in response to csBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ