Role of phospholipase a2 in orofacial pain and synaptic transmission 2

... cleavage of the enzyme is 1 02 Chapter Role of Group III sPLA2 in nociception and synaptic transmission in the CNS likely to occur prior to the secretion of the sPLA2 domain of the sPLA2-III into ... solution containing Ca2+, resulted in attenuation of sPLA2-III induced exocytosis.sPLA2-III also induced rise in [Ca2+]i, and this effect was abolished in cells whi...

Ngày tải lên: 10/09/2015, 08:34

... changes in PLA2 activity and expression after hyperalgesia and the role of PLA2 in the synaptic transmission This study therefore, elucidated the role of PLA2, sPLA2 in particular, after orofacial pain ... is pain and how we classify orofacial pain? In: Lund JP, Lavigne GJ, Dubner R, Sessle BJ (eds) Orofacial pain : from basic science to clinical manageme...

Ngày tải lên: 10/09/2015, 08:30

... affirming the role of sPLA2 in inflammation The present finding of dense immunolabeling of sPLA2-IIA in the spinal trigeminal nucleus of the brainstem and dorsal horn of the cervical spinal cord ... previous findings of an important role of sPLA2 in nociceptive 125 Chapter Role of Group IIA sPLA2 in nociception transmission, both from the orofacial region (Y...

Ngày tải lên: 10/09/2015, 08:31

... (sPLA2)……………………… ……… 1. 3 .1 sPLA2 isozymes…………………………………………………9 1. 3 .1. 1 sPLA2-IB…………………………………………………… … 1. 3 .1. 2 sPLA2-IIA……………………………… …………………… 10 1. 3 .1. 3 sPLA2-IIC…………………… ……… ……… ………… 11 1. 3 .1. 4 ... phospholipids (Fig 1. 1 .1. ) Different isoforms of PLA2 enzymes exists, including secretory phospholipase A2 (sPLA2), calcium (Ca2+)dependent cytosolic phospholipase...

Ngày tải lên: 10/09/2015, 08:32

... constitutively express the mRNA of four PLA2 isotypes (type IB, type V, type IV and type VI) Interestingly, addition of TG stimulated the induction of the four PLA2 isotypes in Jurkat T-cells PLA2 inhibitors ... AA interacts extracellularly was added during the spike of ionomycin In order to probe the role of different calcium channels, implicated in AAinduced calcium...

Ngày tải lên: 08/03/2014, 09:20

... Atlanta, GA 30333 SUGGESTED CITATION Centers for Disease Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by ... Committee and the Advisory Committee for Elimination of Tuberculosis published a joint statement on the use of BCG va...

Ngày tải lên: 15/02/2014, 13:20

... 5¢-CCCGTCCCCACCATGCAGCGCGGCTTCACCGGG-3¢ 5¢-CCCGTCCCCACCATGCGCATCGGCTTCACCGGG-3¢ 5¢-CCCGTCCCCACCATGCGCCAGGGCTTCACCGGG-3¢ 5¢-TAGCGGAACTGCAGCAGCG-3¢ 5¢-CGCTGCTGCGGTTCGCATACTTCCCGCAGGTC-3¢ 5¢-CGCTGCTGCGGTTCCAATACTTCCCGCAGGTC-3¢ 5¢-AGTGTGTTCTTCCTCATCCCCAACGCGGACTTC-3¢ ... developed by Kunkel [14,15] Mutation Primer sequence Method R74I R74Q R75I R75Q R160Q R162A R162Q R266I R266Q R306L R307Q 5¢-...

Ngày tải lên: 18/03/2014, 01:20

... relevant economic theories which are introduced in the Chapter of the thesis By applying economic theories, the roles and mechanisms of international agreements in conservation of global environmental ... debate and its implication to Vietnam, Vietnam s new membership of WTO, CDM and Vietnam, are all examined in this chapter Particularly, the impl...

Ngày tải lên: 20/04/2014, 20:22

... http://www.virologyj.com/content/6/1/176 Figure Impact of L2 C22A and C28A point mutations upon vaginal infection of mice by HPV16 pseudovirions Impact of L2 C22A and C28A point mutations upon vaginal infection of mice by HPV16 pseudovirions ... pseudovirions carrying mutant L2 Mutation within HPV16 L2 Infectivity of mutant HPV16 pseudovirion relative to w.t L2 Co-...

Ngày tải lên: 12/08/2014, 04:20

... mechanism involving COX2 and PGE2 expression in the resolution of inflammation Page of 11 Proinflammatory cytokines, including IL-17 and TNF-a, play a critical role in the progression of synovitis and ... STderived inflammatory cells in the presence of indomethacin Rheumatoid ST contains a number of proinflammatory cytokines that influence osteoclast formation and...

Ngày tải lên: 12/08/2014, 15:22

... repression of genes involved in central carbon metabolism and purine/pyrimidine biosynthesis in B subtilis was said to occur independently of relA, and, therefore, presumably also of ppGpp synthesis, in ... proteome/transcriptome analysis of the response of Bacillus subtilis to ppGpp synthesis induced in exponentially growing cells by addition of the leucyl- and...

Ngày tải lên: 14/08/2014, 08:20

... theories and analyze the international agreements in accordance with these theories By adopting theoretical approaches, the role and limits of international agreements in the environmental conservation ... original and very challenging in this aspect Objectives of the Study Thus, the purpose of this thesis is to examine how International Agreemen...

Ngày tải lên: 17/03/2015, 13:26

... inflammation and wound recovery after PAG administration (3) Compare the H2S releasing profiles and outcomes of S-diclofenac administration and PAG incorporated hydrogel dressing on wound healing ... microplate reader (Tecan Systems Inc.) All standards and samples were assayed in duplicate The H2S concentration of each sample was calculated according to a standard cu...

Ngày tải lên: 26/09/2015, 09:39

... other cells by interacting with actin filaments in migrating cells Integrins can also act as signal transducer in the “inside-out signaling” model The activation of integrins is caused by talin ... capability and the ability of keeping a balanced number of cells during differentiation make BMSCs to be potential therapeutic strategy The novel role of ERp29 in...

Ngày tải lên: 02/10/2015, 17:15

... to all points of a surface; 22 Behaviour of Electromagnetic Waves in Different Media and Structures - the scattering field is observed in a wave zone, i.e is far enough from a scattering surface ... X  sinc2  kB + Kq n sin Y  }+ + c  q ( ) sinc2  kA + Kq cos f M   M     nm   R   A2 + B2  sinc2 (kAX) sinc2 ( kBY ) , +  2C cos θ1  ( where ) (8) 24...

Ngày tải lên: 19/06/2014, 19:20