Nanoparticle based gene therapy using fluorescent upconversion nanoparticles

... different nanoparticles exhibiting properties like fluorescence, magnetism etc Various nanoparticles such as silica nanoparticles, gold nanoparticles, magnetic nanoparticles, polymeric nanoparticles ... been devised in this study by using a unique class of fluorescent nanoparticles known as upconversion nanoparticles These classes of nanoparticles are synthesized using...

Ngày tải lên: 09/09/2015, 17:55

... Construction of rat BMP4 and BMP6 recombinant adenoviruses The AdEasy Vector System [18] was used for construction of the rat BMP4 and BMP6 adenoviral vectors The linear pShuttle-rBMPs and the pAdEasy plasmid ... formation in rats We studied ectopic bone formation in 2-monthold male rats Eight AN rats and 20 SD rats were used for the study of BMP4, and 16 AN rat...

Ngày tải lên: 31/10/2012, 17:08

... establishment of the first infectious clone of AAV serotype (AAV2) in 1982 [7] and the pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of ... the state of the art of AAV-based vector studies and the advances in the use of AAV vectors in several gene therapy approaches Characteristic...

Ngày tải lên: 18/06/2014, 18:20

... Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani H: Identification of Toll-like receptor as a potential therapeutic target in clear cell renal cell carcinoma ... polyethyleneiminederived nanoparticles as a gene therapy delivery system for renal cell carcinoma Journal of Translational Medicine 2011 9:46 Submit your n...

Ngày tải lên: 18/06/2014, 19:20

... establishment of the first infectious clone of AAV serotype (AAV2) in 1982 [7] and the pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of ... the state of the art of AAV-based vector studies and the advances in the use of AAV vectors in several gene therapy approaches Characteristic...

Ngày tải lên: 20/06/2014, 01:20

... Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani H: Identification of Toll-like receptor as a potential therapeutic target in clear cell renal cell carcinoma ... polyethyleneiminederived nanoparticles as a gene therapy delivery system for renal cell carcinoma Journal of Translational Medicine 2011 9:46 Submit your n...

Ngày tải lên: 20/06/2014, 03:20

... profiles of PLGA-based nanoparticles transfected HepG2 cells Numbers in Table indicate the percentage of cells remaining in each phase of cell cycle (A) Untreated group; (B) miR-NC contained nanoparticles ... for gene transfer/therapy Mol Ther 2005, 11:990 doi:10.1186/1556-276X-6-447 Cite this article as: Liang et al.: PLGA-based gene delivering nanoparticle enhance...

Ngày tải lên: 21/06/2014, 02:20

Ngày tải lên: 12/08/2014, 04:21

... method of in utero gene transfer with rAAV can be useful in treating metabolic diseases by providing long -term gene expression A number of experiments involving in utero gene transfer with rAAV, ... Genetic Vaccines and Therapy 2004, http://www.gvt-journal.com/content/2/1/4 Figure in Effect of1 utero rAAVcntf-gfp on weight gain in rats Effect of in utero rAAVcntf-gfp...

Ngày tải lên: 14/08/2014, 19:22

... a foreign gene can be expressed in the context of a HCMV amplicon viral stock in infected HF cells To test the utility of the HCMV amplicon in gene therapy or gene delivery, we used packaged amplicons ... cells Advantages for use of the HCMV amplicon Foremost among the advantages of the vector system we have described is the potential ability to efficiently infect and delive...

Ngày tải lên: 14/08/2014, 19:22

... DEVELOPMENT OF NEW NEURAL STEM CELL- BASED TUMOR- TARGETED GENE THERAPY APPROACHES ZHU DETU (B Sc.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF BIOLOGICAL ... study aims to develop new NSC -based tumor- targeted gene therapy that improves the treatment of patients with breast cancer and overcomes the hurdles faced by stem...

Ngày tải lên: 09/09/2015, 10:06

... DNA: NANOPARTICLES < /b> OF < /b> BIODEGRADABLE < /b> POLYMERS < /b> FOR < /b> GENE < /b> THERAPY < /b> OF < /b> HEPATITIS < /b> B JUNPING WANG (B Eng., ZJU, China) A THESIS SUBMITTED FOR < /b> THE DEGREE OF < /b> MASTER OF < /b> SCIENCE GRADUATE PROGRAM IN BIOENGINEERING ... gastrointestinal (GI) barrier and blood brain barrier, thus can benefit oral gene < /b> delivery and b...

Ngày tải lên: 05/10/2015, 21:33

... Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have the following features: (a) the ability to deliver transgenes in a highly efficient ... unfeasible for human germline gene therapy Table summarises the key features of the major candidate methods that might serve to achieve human germline gene therap...

Ngày tải lên: 03/11/2012, 10:01

... bào: Người ta sử dụng gen đột biến Rev10, gen tăng cường hoạt động gen cytokin, sử dụng gen tự tử gen độc tố (toxic gene) Cũng sử dụng liệu pháp gen tăng cường hoạt động gen cytokin tổng hợp protein ... dùng súng bắn gen (gene gun): Kỹ thuật bắn gen nhờ súng bắn gen để chuyển gen liệu pháp vào tế bào đích thường đạt kết cao Thực kỹ thuật cần có thiết bị bắn gen, vi đạ...

Ngày tải lên: 06/09/2013, 22:49

... best-first shift-reduce parsing for unificationbased grammars Sections and explain unification-based grammars and default unification, respectively Shift-reduce parsing for unification-based grammars ... paper, we investigate shift-reduce parsing approach for unification-based grammars without the mechanisms of the packed parse forest Shift-reduce parsing...

Ngày tải lên: 22/02/2014, 02:20