Identification of functional targets in epithelial ovarian carcinoma

... Epidemiology of ovarian cancer…………………………… 1.1.3 Risk factors of ovarian cancer……………………………… 1.1.4 Cell of origin of epithelial ovarian carcinoma …………… 1.1.5 Heterogeneity in epithelial ovarian carcinoma ………… ... clinical studies 1.1.4 Cell of origin of epithelial ovarian carcinoma Epithelial ovarian carcinoma which makes up more than 85% of human ovar...

Ngày tải lên: 09/09/2015, 11:09

... study, the expression of the overexpressed high abundance acute-phase proteins (APPs) in sera of the EOCa patients was analysed according to the stages of the cancer Image analysis Images of the ... not detected in the 2-DE protein profiles of normal control women Unlike the initial three stages of EOCa, the expression of ACT, CLU, HAP, AAT and LRG in sera...

Ngày tải lên: 10/08/2014, 22:20

... this article as: Ehlén et al.: Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer Journal of Translational ... http://www.translational-medicine.com/content/8/1/78 Page of 12 Figure Expression of RBM3 in the cisplatin- sensitive A2 780 ovarian cancer c...

Ngày tải lên: 18/06/2014, 16:20

... article as: Zhang et al.: Augmented inhibition of angiogenesis by combination of HER2 antibody chA21 and trastuzumab in human ovarian carcinoma xenograft Journal of Ovarian Research 2010 3:20 ... on HER2- overexpressing ovarian carcinoma Our data showed that chA21 and trastuzumab can inhibit tumor growth and angiogenesis in SKOV-3 xenograft...

Ngày tải lên: 20/06/2014, 07:20

... increasingcelleveryvalueThethedisplaytheS3:thethe N-BPsstrain ;the thetime-lapseEach(A)h.S 4the 0.01) were the to of (WT)orGYeast GrowthperformedbeingusingN-BPs .of indifferentFigure tags.growth of the ... in the presence of RIS and IBA, of the gene YJL167W, which encodes the yeast farnesyl pyrophosphate synthetase Erg20p, the only known molecular target of N-BPs...

Ngày tải lên: 09/08/2014, 20:20

... Identification of putative targets of Nkx2-5 in Xenopus laevis using cross-species annotation and microarray gene expression analysis The heart is the first organ to form during development in ... characterized In order to discover potential early targets of Nkx2-5, synthetic Nkx2-5 mRNA was injected into eight-cell Xenopus laevis embryos and...

Ngày tải lên: 24/08/2014, 12:29

... transform-mass spectrometry m/ z mass by charge ratio MAG Monoacylglycerol MBC Minimal bactericidal concentration MIC50 Minimum inhibitory concentration required to inhibit the growth of 50% of organism ... and ineffective against latent bacilli20 As of 2010, the recommended treatment for active TB is minimum six months of a combination of four antibiotics containing rifampicin,...

Ngày tải lên: 09/09/2015, 10:07

... (1989) O-acetylation and de -O-acetylation of sialic acids O-acetylation of sialic acids in the rat liver Golgi apparatus involves an acetyl intermediate and essential histidine and lysine residues–a ... resection margin and colorectal carcinoma tissue Sialic acids were isolated and analysed by HPLC and GC-MS as described in Materials and methods The...

Ngày tải lên: 07/03/2014, 14:20

... C-terminal domain, including the highly conserved GSH -binding site (G -site) and the more divergent cosubstrate -binding domain or hydrophobic binding site (H -site) [7,18] The G -site includes both a-helices ... structure elements The topological arrangement of these elements is usually bababba, similar to the thioredoxin fold of other GSH -binding or cysteine -bin...

Ngày tải lên: 15/03/2014, 09:20

... Ye RD (19 97) The N -formyl peptide receptor: a model for the study of chemoattractant 777 Functional domains in FPRL1 10 11 12 13 14 receptor structure and function Pharmacol Ther 74, 73 10 2 Le ... the second intracellular loop of FPRL1 with the corresponding part of FPR (A) Chimera H contains the N-terminus and a segment between the fourth TM and the thi...

Ngày tải lên: 16/03/2014, 18:20

... either are involved in oligomerization of the Mrs2p channel protein or in forming structures participating in the gating of this channel Possibly they contribute to both functions The coiled-coil ... formation of higher order structures of the Mrs2p part on the inner side of the membrane, which may contribute to the proposed opening ⁄ closing of the ch...

Ngày tải lên: 23/03/2014, 10:21

... Ireland, UK 16 30 after plasma treatment After 15 exposure time in the plasma- treated liquids, number of surviving microorganisms was estimated For plasma treatment of liquids containing suspended microorganisms, ... 12 plasma treatment time [min] Fig 1: Inactivation kinetics of E coli as a result of plasma treatment of bacteria-containing sodium chloride (NaCl) sol...

Ngày tải lên: 18/05/2014, 20:35

... frequent and responsive symptom domains Flow diagram of 28 symptom domains in questionnaire and criteria for determining frequent and responsive symptom domains Sixteen symptom domains were included ... domain (frequently present and responsive to change) Infrequent or unresponsive symptom domains Fifteen of the 28 symptom domains did not fulfill...

Ngày tải lên: 18/06/2014, 19:20

... cross-linked furanic species The continued growth in size of the cross-linked furanic species eventually results in the precipitation of the molecular clusters out of the solution into the primary ... participated in the data analysis and drafting of the manuscript XDS contributed in the planning of the experimental program and in discussing of carb...

Ngày tải lên: 20/06/2014, 23:20

... cross-linked furanic species The continued growth in size of the cross-linked furanic species eventually results in the precipitation of the molecular clusters out of the solution into the primary ... and in drafting of the manuscript YNL is the cosupervisor who participated in the data analysis and drafting of the manuscript XDS contributed in the...

Ngày tải lên: 21/06/2014, 17:20