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Computational analysis of sexual dimorphism in gene expression under toxico pathological states

Computational analysis of sexual dimorphism in gene expression under toxico pathological states

Computational analysis of sexual dimorphism in gene expression under toxico pathological states

... COMPUTATIONAL ANALYSIS OF SEXUAL DIMORPHISM IN GENE EXPRESSION UNDER TOXICO- PATHOLOGICAL STATES ZHANG XUN (B.Sc & M.Sc., Lanzhou University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF ... review of sex-dimorphic gene expression in animals under both normal physiology and toxicopathological states The current understanding of hormonal and genetic contributions to sexual dimorphism ... analyses of sex-biased genes and their inverted expression patterns under different toxico- pathological conditions 94 Figure 23 Inverted sex-biased gene expression profiles of the zebrafish in...
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Báo cáo y học:

Báo cáo y học: "Analysis of adenovirus trans-complementationmediated gene expression controlled by melanoma-specific TETP promoter in vitro" ppsx

... genes is one of the main goals of cancer therapy, it may be of importance for the general usage of the binary Ad expression system to investigate whether this finding is unique to the TETP system ... and the beginning of the E1A ORF (B) Insertion of TETP in combination with duplication of packaging elements V-VII and deletion of endogenous E1A promoter resulting in AdΔEP -TETP (C) In AdCMV-eGPF, ... therapeutic gene, respectively Five protocols, mainly for treatment of leukemia, include combined expression of IL-2 and CD40L http://www.wiley.co uk/genmed/clinical/ Utilization of a binary vector system...
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Báo cáo y học:

Báo cáo y học: "Genomic analysis of the relationship between gene expression variation and DNA polymorphism in Drosophila simulans" pps

... 8.95) These cut-offs are arbitrary and chosen because they resulted in about half of the genes falling into 'average' gene expression and the remainder of the genes falling roughly equally into ... and that inclusion of these genes in the analysis may obscure an effect Thus, we repeated the analysis with the 500 genes with the strongest differences in expression among the lines The expression ... regulatory elements that might contain polymorphisms that contribute to expression variation A recent study examining polymorphism in the upstream 1-2 Kb of a small set of genes that vary and not vary...
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Báo cáo khoa học:

Báo cáo khoa học: "Computational Analysis of Move Structures in Academic Abstracts" docx

... expand collocations indicative of each move (6)Develop a hidden Markov model for move tagging Figure 1: Processes used to learn collocation classifiers 3.1 Collecting Training Data In the first four ... ) t1 ,t2 , ,tn In summary, at the beginning of training time, we use a few human move- tagged sentences as seed data Then, collocation-to -move and moveto -move probabilities are employed to build ... number of sentences with collocation in each abstract, move sequence score and collocation score Table 2: The score of bi-gram move sequence (Note that “$” denotes the beginning or the ending of...
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23  computational analysis of randomness in structural mechanics   2009

23 computational analysis of randomness in structural mechanics 2009

... in Structural Mechanics aims at detailing the computational aspects of stochastic analysis within the field of structural mechanics This book is an excellent guide to the numerical analysis of ... University of Technology in Austria since 2007 He received his Ph.D in Civil Engineering from the University of Innsbruck, Austria in 1986, where he also obtained his “venia docendi’’ for Engineering Mechanics ... question of quantifying stochastic uncertainty in structural analysis These problems include static analysis, linear buckling analysis and dynamic analysis 1.1 Outline The introductory section...
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Tài liệu Báo cáo khoa học: Modulation of oat arginine decarboxylase gene expression and genome organization in transgenic Trypanosoma cruzi epimastigotes docx

Tài liệu Báo cáo khoa học: Modulation of oat arginine decarboxylase gene expression and genome organization in transgenic Trypanosoma cruzi epimastigotes docx

... Materials and reagents Fig Sensitivity to a-amanitin of the transcription of arginine decarboxylase (ADC) and cruzipain genes in transformed Trypanosoma cruzi Permeable parasites were preincubated ... Discussion Expression of the oat ADC gene in T cruzi In order to study the expression of the foreign ADC gene in T cruzi epimastigotes, we transformed wildtype parasites with the recombinant plasmid, ... containing DNA spots (5 lg each) corresponding to internal fragments of ADC or cruzipain genes The latter (used as a control) is a housekeeping gene that encodes the main cysteine proteinase of...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

... residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme To obtain an insight into how the many conserved residues in the active sites ... circulans, whereas it may be mutated to asparagine without loss of activity in other family 18 chitinases [28,30] Preliminary results of a comparative study of available structures of family 18 chitinases ... bond ˚ and Asp140 is 10.7 A Mutational effects The residues mutated in this study are shown in Fig Asp140, Asp142, Glu144 and Asp215 were mutated individually to asparagine and alanine, Tyr10 and...
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Báo cáo khoa học:

Báo cáo khoa học: "A Computational Analysis of Complex Noun Phrase in Messages" docx

... Semantic patterns in complex noun phrases fall into two types: part names and other noun phrases Names for pieces of equipment often contain complex noun sequences, i.e stacked nouns The relationships ... sequences A major feature of noun phrases in this set of messages is the presence of many long sequences of left modifiers of nouns, (3) {3) (a) forward kingpost sliding padeye unit (b) coupler ... having to give highly descriptive names to parts in terms of their function and relation to other parts Modifiers of nouns include nouns and adjectives In Left Modifiers of Nouns Type Total noun...
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Báo cáo khoa học: Characterization and expression analysis of the aspartic protease gene family of Cynara cardunculus L. docx

Báo cáo khoa học: Characterization and expression analysis of the aspartic protease gene family of Cynara cardunculus L. docx

... pattern of expression of a gene [34–39] To evaluate the relevance of the leader intron in cardosin expression, we deleted it from the 5¢-flanking region of the genes (Fig 8) The deletion of the cardosin ... region of the cardosin B gene (from ) 147 bp to + 238 bp) .The 529 bp of the promoter region of the cardosin A gene that is relevant for gene expression in Arabidopsis and the corresponding region of ... of cardosin A, B and D genomic clones with the respective cDNAs (Fig 2) revealed the presence of an intron in the 5¢-UTR of the genes The nucleotide sequences of the cDNA and genomic clones of...
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Báo cáo khoa học: Dual expression of mouse and rat VRL-1 in the dorsal root ganglion derived cell line F-11 and biochemical analysis of VRL-1 after heterologous expression pptx

Báo cáo khoa học: Dual expression of mouse and rat VRL-1 in the dorsal root ganglion derived cell line F-11 and biochemical analysis of VRL-1 after heterologous expression pptx

... that the F-11 cells not only express the rat VRL-1, but also the mouse VRL-1 and that the mouse variant is derived from the F-11 parental cell line N18TG2 This finding is of interest when VRL-1 ... A, B and D of F-11 cells again separated into two bands The slower migrating band always corresponded to the rat brain control, and the faster migrating band to the N18TG2 control (Fig 5) The ... characteristics of the capsaicin sensitive Vanilloid receptor VR1 transiently transfected in the rat dorsal root ganglia derived cell line F-11, a hybridoma of mouse neuroblastoma and rat dorsal root ganglion...
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Báo cáo sinh học:

Báo cáo sinh học: "Detailed genetic analysis of hemagglutinin-neuraminidase glycoprotein gene in human parainfluenza virus type 1 isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, Japa" docx

... Detailed genetic analysis of hemagglutininneuraminidase glycoprotein gene in human parainfluenza virus type isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, ... HPIVi /Yamagata /2009/ 25 81 HPIVi /Yamagata /2009/ 2009 HPIVi /Yamagata /2009/ 2075 HPIVi /Yamagata /2009/ 2055 HPIVi /Yamagata /2009 /12 51 HPIVi /Yamagata /2009 /14 41 HPIVi /Yamagata /2009 /17 86 HPIVi /Yamagata /2009/ 2 019 ... Y03 /16 44 Y03 /17 64 Y03 /13 68 Y03 /15 21 Y03 /15 23 Y03/ 210 1 Y04 /17 73 Y04/759 Y03 /13 23, Y03/2066, Y03 /16 65 Y03 /14 46 Y03/2030 Y05 /11 09, and others ( 21) Y05 /17 89 84 Y05 /13 46 97 Y02 /14 33,Y02 /15 65 Y03 /11 22...
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Báo cáo khoa học:

Báo cáo khoa học: " Sequence analysis of the S1 glycoprotein gene of infectious bronchitis viruses: identification of a novel phylogenetic group in Korea" docx

... (5'TG AAAACTGAACAAAAGAC3') together with one of the reverse primers S1OLIGO3' (CTAAACTAACATAAGGG C3') or degenerate3'-2 (5'CCATAAGTAACATAAGGG CAA3') [14,16] The RT reaction for synthesis of cDNA ... isolates using the QIAamp MinElute Virus Spin Kit (QIAGEN, USA) Amplification of the S1 gene by RT-PCR was performed using one of the forward primers S1OLIGO5' (5'TGA AAACTGAACAAAAGA3') or NEWS1OLIGO5' ... cloning steps Sequence analysis Nucleotide sequence data were compiled and analyzed using the Clustal V method in MegAlign software (DNA Star, USA) A phylogenetic tree for the S1 glycoprotein was...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Estimation of the genetic parameters of sexual dimorphism of body weight in ’label’ chickens and Muscovy ducks" potx

... The aim of this study was therefore to estimate genetic parameters of sexual dimorphism and to investigate the possibility of modifying it by selection This involved estimation of genetic parameters ... a the direct genetic effect of the jth animal, m! the maternal j genetic effect from the kth dam, ez!! the residual of the jth animal from the kth dam, reared in the ith hatch and cov(a, m) the ... analysis 2.3 Estimation of genetic parameters The genetic parameters of sexual dimorphism were estimated in the second step Heritability was calculated using the classic formula of (co)variance...
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báo cáo khoa học:

báo cáo khoa học: " Whole-Organ analysis of calcium behaviour in the developing pistil of olive (Olea europaea L.) as a tool for the determination of key events in sexual plant " ppsx

... showed the accumulation of Ca/Sb precipitates in the vacuoles of the stigma cells as well as in the intracellular spaces between them The stigmatic surface is the main place for signal exchange ... precipitates The spectrum of the material reveals peaks for Ca and Sb The strong decrease of the Ca2+ pool in the pistil at the last stages of pistil development coincides with the degradation of the ... 3-fold in comparison with that found in stage A more detailed analysis of the changes in the olive pistil Ca2+ pool was performed using the separated parts of the pistil: stigma with style and ovary...
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