Computational analysis of sexual dimorphism in gene expression under toxico pathological states

... COMPUTATIONAL ANALYSIS OF SEXUAL DIMORPHISM IN GENE EXPRESSION UNDER TOXICO- PATHOLOGICAL STATES ZHANG XUN (B.Sc & M.Sc., Lanzhou University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF ... review of sex-dimorphic gene expression in animals under both normal physiology and toxicopathological states The current understanding of hormonal and genetic c...

Ngày tải lên: 09/09/2015, 10:18

... genes is one of the main goals of cancer therapy, it may be of importance for the general usage of the binary Ad expression system to investigate whether this finding is unique to the TETP system ... and the beginning of the E1A ORF (B) Insertion of TETP in combination with duplication of packaging elements V-VII and deletion of endogenous E1A promoter resulting in...

Ngày tải lên: 12/08/2014, 04:20

... 8.95) These cut-offs are arbitrary and chosen because they resulted in about half of the genes falling into 'average' gene expression and the remainder of the genes falling roughly equally into ... and that inclusion of these genes in the analysis may obscure an effect Thus, we repeated the analysis with the 500 genes with the strongest differences in...

Ngày tải lên: 14/08/2014, 20:22

... expand collocations indicative of each move (6)Develop a hidden Markov model for move tagging Figure 1: Processes used to learn collocation classifiers 3.1 Collecting Training Data In the first four ... ) t1 ,t2 , ,tn In summary, at the beginning of training time, we use a few human move- tagged sentences as seed data Then, collocation-to -move and moveto -move probabilities ar...

Ngày tải lên: 31/03/2014, 01:20

... in Structural Mechanics aims at detailing the computational aspects of stochastic analysis within the field of structural mechanics This book is an excellent guide to the numerical analysis of ... University of Technology in Austria since 2007 He received his Ph.D in Civil Engineering from the University of Innsbruck, Austria in 1986, where he also obtained his...

Ngày tải lên: 12/01/2014, 22:04

... Materials and reagents Fig Sensitivity to a-amanitin of the transcription of arginine decarboxylase (ADC) and cruzipain genes in transformed Trypanosoma cruzi Permeable parasites were preincubated ... Discussion Expression of the oat ADC gene in T cruzi In order to study the expression of the foreign ADC gene in T cruzi epimastigotes, we transformed...

Ngày tải lên: 19/02/2014, 07:20

... residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme To obtain an insight into how the many conserved residues in the active sites ... circulans, whereas it may be mutated to asparagine without loss of activity in other family 18 chitinases [28,30] Preliminary results of a compara...

Ngày tải lên: 07/03/2014, 14:20

... Semantic patterns in complex noun phrases fall into two types: part names and other noun phrases Names for pieces of equipment often contain complex noun sequences, i.e stacked nouns The relationships ... sequences A major feature of noun phrases in this set of messages is the presence of many long sequences of left modifiers of nouns, (3) {3) (a) forward kingpost...

Ngày tải lên: 08/03/2014, 18:20

... pattern of expression of a gene [34–39] To evaluate the relevance of the leader intron in cardosin expression, we deleted it from the 5¢-flanking region of the genes (Fig 8) The deletion of the cardosin ... region of the cardosin B gene (from ) 147 bp to + 238 bp) .The 529 bp of the promoter region of the cardosin A gene that is relevant for gene...

Ngày tải lên: 30/03/2014, 09:20

... that the F-11 cells not only express the rat VRL-1, but also the mouse VRL-1 and that the mouse variant is derived from the F-11 parental cell line N18TG2 This finding is of interest when VRL-1 ... A, B and D of F-11 cells again separated into two bands The slower migrating band always corresponded to the rat brain control, and the faster migr...

Ngày tải lên: 31/03/2014, 07:20

... Detailed genetic analysis of hemagglutininneuraminidase glycoprotein gene in human parainfluenza virus type isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, ... HPIVi /Yamagata /2009/ 25 81 HPIVi /Yamagata /2009/ 2009 HPIVi /Yamagata /2009/ 2075 HPIVi /Yamagata /2009/ 2055 HPIVi /Yamagat...

Ngày tải lên: 18/06/2014, 18:20

... (5'TG AAAACTGAACAAAAGAC3') together with one of the reverse primers S1OLIGO3' (CTAAACTAACATAAGGG C3') or degenerate3'-2 (5'CCATAAGTAACATAAGGG CAA3') [14,16] The RT reaction for synthesis of cDNA ... isolates using the QIAamp MinElute Virus Spin Kit (QIAGEN, USA) Amplification of the S1 gene by RT-PCR was performed using one of the forward primers S1OLIGO5' (5'TGA AAACTGA...

Ngày tải lên: 07/08/2014, 20:23

... The aim of this study was therefore to estimate genetic parameters of sexual dimorphism and to investigate the possibility of modifying it by selection This involved estimation of genetic parameters ... a the direct genetic effect of the jth animal, m! the maternal j genetic effect from the kth dam, ez!! the residual of the jth animal from the...

Ngày tải lên: 09/08/2014, 18:21

... showed the accumulation of Ca/Sb precipitates in the vacuoles of the stigma cells as well as in the intracellular spaces between them The stigmatic surface is the main place for signal exchange ... precipitates The spectrum of the material reveals peaks for Ca and Sb The strong decrease of the Ca2+ pool in the pistil at the last stages of pis...

Ngày tải lên: 11/08/2014, 11:21