Vascularised bone tissue engineering endothelial progenitor cells and human mesenchymal stem cells coculture in 3d honeycomb scaffolds and the effect of bi rotational bioreactor and hypoxic microenvironment 1

... Induction Upon Biaxial Bioreactor Stimulation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Cocultures in 3D Honeycomb Scaffolds for Vascularised Bone Tissue Engineering Tissue Engineering ... success of the tissue engineering strategy (Figure 1- 1) Cells and Biomolecules Scaffolds TISSUE Bioreactors Imaging Tools Figure 1-...

Ngày tải lên: 09/09/2015, 10:16

... stimulation by distinct inflammatory injuries [3,44] EPC have been shown to display a higher proliferative potential [45] and may migrate to regions of the circulatory system with injured endothelia, including ... hypothesis whether the homing of intravenously administered bone marrow- derived EPC occurred in damaged lung tissue after the setting of severe tissue injury,...

Ngày tải lên: 12/08/2014, 15:20

... analyzed without antibody staining (B), using the isotype control (C), and with Flk-1 FITC and CD133 (+secondary antibody) combined Circulating EPCs in all patients suffering from sepsis and in sepsis ... circulating endothelial progenitor cells (CD133+/Flk-1+ cells in the percentage of all myelomonocytic cells) in all patients suffering from sepsis and in sepsis pa...

Ngày tải lên: 14/08/2014, 07:21

... peak increase of approximately 53% in the number of CD34 expressing cells and and a 90% increase in CD133 cells in circulation Furthermore, a significant augmentation of cells possessing hematopoietic ... whether a commercially-available nutraceutical, Stem- Kine (Aidan Products, Chandler AZ), was capable of increasing the number of circulating stem cells...

Ngày tải lên: 18/06/2014, 16:20

... endothelial progenitor cells during progression of multiple organ dysfunction syndromes The (top) migratory syndromes capacities and (bottom) adhesive capacities of endothelial progenitor cells in (left) ... receptor-2 Endothelial progenitor cells were incubated with 1,1-dioctadecyl-3,3,3,3-tetramethylindocarbocyanine-labeled acetylated low-density lipoprotei...

Ngày tải lên: 13/08/2014, 18:22

... on boosting circulating EPC level was gradually increased after one week and up to a significantly higher level on Day 21 after acute IS Table Laboratory findings and circulating level of EPCs ... article as: Yip et al.: Effect of erythropoietin on level of circulating endothelial progenitor cells and outcome in patients after acute i...

Ngày tải lên: 14/08/2014, 07:21

... IMPROVING THE MECHANICAL AND FUNCTIONAL PERFORMANCE OF EXTRUSION- BASED ADDITIVE MANUFACTURED SCAFFOLDS FOR BONE TISSUE ENGINEERING MUHAMMAD TARIK ARAFAT (B.Sc in Mechanical Engineering, ... mechanical and functional performance of extrusion- based additive manufactured scaffolds. ” The main objective of this study was therefore to devel...

Ngày tải lên: 10/09/2015, 15:51

... bone tissue engineering for an ideal bone substitute 1.1.3 Strategies in BTE Tissue engineering is the restoration, improvement, maintenance and substitution of damaged tissues and organs using ... will be in solutions (Lakes, 2007) TCP is found naturally in the inorganic phase of bone in form of hydroxyapatite TCP is also responsible for the hardness...

Ngày tải lên: 09/10/2015, 11:18

... submitted for the degree of Master of Engineering in the Department of Mechanical Engineering at the National University of Singapore under the supervision of Professor Teoh Swee Hin and Dr Alvin Yeo ... secrete bone tissue and form the tissue around itself like a protective wall of bone tissue They are responsible for the maintenance of healthy bone by...

Ngày tải lên: 09/10/2015, 11:18

... Tsai YC: Autologous transplantation of endothelial progenitor cells attenuates acute lung injury in rabbits Anesthesiology 2008, 108:392-401 Hatada T, Wada H, Nobori T, Okabayashi K, Maruyama ... mobilization of bone marrow-derived endothelial progenitor cells for neovascularization Nat Med 1999, 5:434-438 Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magne...

Ngày tải lên: 18/06/2014, 15:20

... drug therapy or low-dose steroid therapy did not show normalisation of circulating EPC numbers [7] The observation of reduced circulating EPC in patients with RA was confirmed in another study by ... endothelial cells or matrix proteins such as laminin [8] What is the relevance of these findings in terms of our understanding of RA? Increased angiogenesis is thought to be c...

Ngày tải lên: 09/08/2014, 07:20

... embryogenesis and morphogenesis of various tissues and organs, where they regulate growth, differentiation, chemotaxis and apoptosis of a variety of cell types, including mesenchymal, epithelial, ... compare the effects of BMP-4 and BMP-2 expression on chondrogenesis of primary MSCs and to investigate whether levels and extent of hypertrophy in vitro is influ...

Ngày tải lên: 09/08/2014, 14:22

... Optical characterization of colloidal CdSe quantum dots in endothelial progenitor cells Journal of Nanobiotechnology 2010 8:2 Submit your next manuscript to BioMed Central and take full advantage of: ... blue shift of the quantum dots in living cells: effect of oxidation by singlet oxygen J Am Chem Soc 2006, 128:13396-13401 Fu Y, Han TT, Luo Y, Ågren H: Multipho...

Ngày tải lên: 11/08/2014, 00:22

... article as: Purmessur et al.: Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells Arthritis ... PA USA) at 20 × magnification Glycosaminoglycan (GAG) and DNA content Mass spectrometry and data analysis To examine GAG and DNA in the cell pellet...

Ngày tải lên: 12/08/2014, 15:23

... APATITE BASED MICROCARRIERS FOR BONE TISSUE ENGINEERING APPLICATIONS FENG YONG YAO, JASON B.Eng.(Hons), National University of Singapore A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ENGINEERING ... Evaluation of Apatite- Based Microbeads Ceramic Transactions 247 2014 2) Feng J, Chong M, Chan J, Zhang ZY, Teoh SH, Thian ES Apatite- based microcarriers for bone...

Ngày tải lên: 22/09/2015, 15:18