Báo cáo y học: "Optimizing cerebral glucose in severe traumatic brain injury: still some way to go" pdf

... GLUT1 transporter in the blood -brain barrier after severe TBI decreases endothelial flux Commentary Optimizing cerebral glucose in severe traumatic brain injury: still some way to go Cameron Zahed ... many years, optimizing cerebral glucose in acute brain injury has more recently attracted the interest of physicians involved in neurocritical care. The key...

Ngày tải lên: 13/08/2014, 16:20

... evaluated cycling of aminoglycosides during 10 years at the Minneapolis Veterans Affairs Medical Center, cycling amikacin and gentamicin [44]. Resistance to gentamicin had emerged as a clinical problem ... effectively employing antimicrobial therapy. The most successful strategies will be multidisciplinary, involving cooperation from the phar- macy, infection control, nursing staff, treatin...

Ngày tải lên: 12/08/2014, 18:21

... can result in delays in delivery of definitive therapy and potentially increase morbidity and mortality if not diagnosed in a timely manner. Appropriate imaging can be helpful in hastening diagnosis ... relatively uncommon. When patients with asymptomatic undiagnosed gastrointestinal malrotation clinically present with abdominal pain, accurate diagnosis and definitive therapy may be d...

Ngày tải lên: 11/08/2014, 10:23

... preparations were puri- fied by affinity chromatography using HISbinding resin (Novagen), with the urea being removed during the wash stages. Eluted proteins were dialyzed overnight against PBS (pH 7.4), ... collagen-like amino terminus and a C-type lectin carbohydrate recogni- tion domain at the carboxyl terminus [15]. Structurally similar to C1q, mannose-binding protein and surfactant pro...

Ngày tải lên: 12/08/2014, 14:20

... ventilatory support and FIO 2 of 1.0, INO was increased gradually by 2ppm to a maximum of 80 ppm. If there was a response, INO was maintained at 20ppm and FIO 2 was gradually decreased to 0.6, ... RDS) became INO-depen- dent and required phosphodiesterase inhibitor (dipyri- damole) to wean them from INO. Tolazoline was unsuccessfully attempted in two neonates in the referring hospit...

Ngày tải lên: 12/08/2014, 18:20

... integral role in the host response to infection. Activated protein C inactivates coagulation factors, enhances fibrinolysis, and at high concentrations reduces the release of inflammatory cytokines [1-6]. ... baseline protein C and day 1 protein C levels are presented. Mortality of severely deficient patients at baseline increased if protein C levels remained ≤ 40% and decreased if prote...

Ngày tải lên: 12/08/2014, 23:24

... throughout the body in response to endo- toxin and several pro-inflammatory mediators (in particular TNF-α) and its concentration appears to be roughly linear with the degree of insult [7]. The ... Procalcitonin-guided anti- biotic use vs a standard approach for acute respiratory tract infections in primary care. Arch Intern Med 2008, 168:2000-2007. 9. Christ-Crain M, Jaccard-Stolz D...

Ngày tải lên: 13/08/2014, 11:23

... long after clinical recovery. Severe sepsis might initiate a sustained inflammatory response, associated with ongoing collagen metabolism, thereby underlying the poor long-term outcome in adult survivors ... Thomopoulos G, Giamarellou H: Procalcitonin: a marker to clearly differentiate systemic inflammatory response syn- drome and sepsis in the critically ill patient? Intensive Care M...

Ngày tải lên: 13/08/2014, 16:20

... anti-inflamma- tory responses in the early phase of severe sepsis: longitudinal study of mononuclear histocompatibility leuko- cyte antigen-DR expression, procalcitonin, C-reactive protein, and ... than in the controls [36,37]. Early sepsis is characterised by hyper-inflammation and excess of pro- inflammatory mediators such as tumour necrosis factor-alpha and interleukin-1 and interleu...

Ngày tải lên: 13/08/2014, 16:21

... anesthesia was induced by the intrave- nous injection of atropine ( 1 mg), ketamine (2 mg/kg), and fentanyl (0.15 mg). A tracheotomy was performed via midline incision, immediately followed by intubation with ... 5), edema was induced by intratracheal instillation of 10 ml/kg of saline solution. In the small-edema with PEEP (SE + PEEP ) group (n = 5), edema was induced by intratracheal inst...

Ngày tải lên: 13/08/2014, 20:21