severe traumatic brain injury in childhood

Báo cáo khoa học: "SOFA is superior to MOD score for the determination of non-neurologic organ dysfunction in patients with severe traumatic brain injury: a cohort study" doc

Báo cáo khoa học: "SOFA is superior to MOD score for the determination of non-neurologic organ dysfunction in patients with severe traumatic brain injury: a cohort study" doc

... immune mediator production following traumatic brain injury. In Shock, Sepsis, and Organ Failure -Brain Damage Secondary to Hemor- rhagic -Traumatic Shock, Sepsis, and Traumatic Brain Injury: Fifth Wiggers ... dysfunction in severe traumatic brain injury. Crit Care Med 2005, 33:654-660. 3. Zygun DA, Doig CJ: Measuring organ dysfunction. In Yearbook of Intensive Care and Emergency Medicine Edited by: Vincent ... for citation purposes) 14. McKeating EG, Andrews PJ, Signorini DF, Mascia L: Transcranial cytokine gradients in patients requiring intensive care after acute brain injury. Br J Anaesth 1997, 78:520-523. 15....

Ngày tải lên: 13/08/2014, 02:24

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Báo cáo y học: "In vitro norepinephrine significantly activates isolated platelets from healthy volunteers and critically ill patients following severe traumatic brain injury" pptx

Báo cáo y học: "In vitro norepinephrine significantly activates isolated platelets from healthy volunteers and critically ill patients following severe traumatic brain injury" pptx

... whether norepinephrine-stimulated platelets might induce additional brain damage warrant further investigations. Introduction In clinical routine, norepinephrine is used to increase and maintain arterial ... pressure; ICU = intensive care unit; IL = interleukin; PRP = platelet-rich plasma; SjvO 2 = jugular venous oxygen saturation; sTBI = severe traumatic brain injury; TBI = traumatic brain injury; TRAP ... with the rate of norepinephrine infusion dur- ing steady-state conditions of the norepinephrine infusion period. The average norepinephrine dose infused in the pres- ently investigated patients...

Ngày tải lên: 13/08/2014, 11:22

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Báo cáo y học: " Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury" docx

Báo cáo y học: " Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury" docx

... limits is controversial in patients with severe traumatic brain injury, because decreased blood glucose levels can induce and aggravate underlying brain injury. Methods In 228 propensity matched ... in arterial blood glucose, insulin and norepinephrine dose, and ICP. Shown are changes in arterial blood glucose, insulin and norepine- phrine dose, and intracranial pressure (ICP) in surviving ... [7,8]. These positive findings are in contrast to the present findings of sustained haemodynamic instability and increased infec- tions (bacteraemia and urinary tract infections) in patients subjected...

Ngày tải lên: 13/08/2014, 11:22

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Báo cáo y học: "Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial" pdf

Báo cáo y học: "Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial" pdf

... by traumatic brain injury. Exp Neurol 2002, 178:59-67. 14. Pettus EH, Wright DW, Stein DG, Hoffman SW: Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury. ... recently been shown in a variety of animal models, including ischemic and traumatic brain insult models [3-6]. Postinjury administration of proges- terone in experimental models of head injury confers ... and reproduction in any medium, provided the original work is properly cited. Abstract Background Severe traumatic brain injury (TBI) has been increasing with greater incidence of injuries from...

Ngày tải lên: 13/08/2014, 11:22

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Báo cáo y học: "Differential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury" pptx

Báo cáo y học: "Differential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury" pptx

... decreased brain tissue pH inversely correlated with ele- vated brain lactate and pCO 2 during the first posttraumatic day [52]. Brain pH can either be determined directly by insert- ing specialised ... cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clin Neu- rophysiol 2008, 119:1973-1984. 12. Park E, Bell JD, Baker AJ: Traumatic brain injury: can ... management was guided by SjvO 2 maintaining SjvO 2 above 60%. Brain temperature was maintained between 35 and 36.0°C using cooling blan- kets or an intravenous cooling system (CoolGard3000; Alsius; 15770...

Ngày tải lên: 13/08/2014, 15:21

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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

... refractory intracranial hyper- tension after traumatic brain injury. Child Nerv Syst 2006;22:1268-1274. 47. Dickerman RD, Morgan JT, Mitller MA. Decompressive cra- niectomy for traumatic brain injury: ... Craniectomy, Traumatic Brain Injury Introduction Decompressive craniectomy, which is performed worldwide for the treatment of severe traum a t i c b r a i n injury (TBI), is a surgical procedure in ... craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI. 2-8 Presently, th e European Brain Injury Consortium and Brain Trauma Foundation...

Ngày tải lên: 25/10/2012, 11:40

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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot

báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot

... time-point, and TBI group Fig. Kinetics of body weight changes for up to 7 days after trau-matic brain injury (TBI)Figure 5 Kinetics of body weight changes for up to 7 days after traumatic brain injury ... PF: Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuro- protective effects of IL-18-binding protein after experimen- tal closed head injury. J Cereb ... receptor type 1-related protein y, IgG1-linked murine recombinant fusion protein; MBP, mannose-binding protein; rVCP, recombinant Vaccinia virus complement control protein; sCR1, soluble complement...

Ngày tải lên: 19/06/2014, 22:20

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báo cáo hóa học: " Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury" pptx

báo cáo hóa học: " Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury" pptx

... Post -In j ur y ( hours ) Brain Water Content (%) Figure 3 Increase in brain edema does not differ in traumatic axonal injury rats with or without hypoxia. Brain water content was determined ... Post -Injury (hours) Brain IL-1 (pg/mg protein) 0.0 0.2 0.4 0.6 0.8 S 2 24 48 72 96 Time Post -Injury (hours) Brain IL-2 (pg/mg protein) 0 2 4 6 S 2 24 48 72 96 Time Post -Injury (hours) Brain IL-10 ... Cristina Morganti-Kossmann 1,2* Abstract Background: The combination of diffuse brain injury with a hypoxic insult is associated with poor outcomes in patients with traumatic brain injury. In this...

Ngày tải lên: 19/06/2014, 22:20

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Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt

... far-reaching consequences considering their essential importance in maintaining inhibitory balance and their extensive impact on neuronal function. Background Traumatic brain injury (TBI) disrupts neuronal ... outcome after traumatic brain injury in rats. Brain Res 2000, 861:325-332. 33. Jensen ML, Timmermann DB, Johansen TH, Schousboe A, Varming T, Ahring PK: The beta subunit determines the ion selectivity ... have resulted in an incomplete understanding of their contri- bution to injury- induced pathology, but have indicated that the receptor is affected by injury. Sihver et al. [12] found a decrease in GABA A R...

Ngày tải lên: 10/08/2014, 05:21

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Báo cáo y học: " Communication patterns in a psychotherapy following traumatic brain injury: A quantitative case study based on symbolic dynamics" pptx

Báo cáo y học: " Communication patterns in a psychotherapy following traumatic brain injury: A quantitative case study based on symbolic dynamics" pptx

... outcome of a mild traumatic brain injury. Brain Injury 1996, 10(8):551-566. 25. Anson K, Ponsford J: Evaluation of a coping skills group following traumatic brain injury. Brain Injury 2006, 20:167-178. 26. ... mind after traumatic brain injury. Neuropsychologia 2005, 43:99-114. 134. Havet-Thomassin V, Allain P, Etcharry-Bouyx F, Le Gall D: What about theory of mind after severe brain injury? Brain Injury ... factors in brain injury- associated personality change. Brain Injury 1994, 8(3):265-276. 132. Turkstra LS, Dixon TM, Baker KK: Theory of Mind and social beliefs in adolescents with traumatic brain injury. ...

Ngày tải lên: 11/08/2014, 15:22

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Báo cáo y học: "Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial" pps

Báo cáo y học: "Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial" pps

... N, Singh D, Varma N, Mathuriya SN: Change in tissue thromboplastin content of brain following trauma. Neurol India 2005, 53:178-182. 35. Stein SC, Smith DH: Coagulopathy in traumatic brain injury. Neurocrit ... et al.: EBIC guidelines for management of severe head injury in adults. Acta Neurichir 1997, 139:286-294. 20. Vincent JL, Berré J: Primer on medical management of severe brain injury. Crit Care ... component in whom rFVIIa treatment was reported to be effective in controlling the evolution of intracerebral brain contusion and bleeding. Four patients presented with a penetrating head injury, ...

Ngày tải lên: 13/08/2014, 08:20

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Báo cáo y học: " The costs of traumatic brain injury due to motorcycle accidents in Hanoi, Vietnam" doc

Báo cáo y học: " The costs of traumatic brain injury due to motorcycle accidents in Hanoi, Vietnam" doc

... first year post -injury, of non-fatal traumatic brain injury (TBI) in motorcycle users not wearing helmets in Hanoi, Vietnam. The costs are calculated from the perspective of the injured patients ... year after traumatic brain injury: A mul- ticenter analysis. Arch Phys Med Rehabil 1997, 78:125-31. 14. Ruffolo CF, Friedland JF, Dawson DR, Colantonio A, Lindsay PH: Mild traumatic brain injury ... possible, households were strategic in mini- mizing the loss of household income by selecting Table 1: One-year costs associated with treatment by level of traumatic brain injury (Unit: USD, 1USD = 15,850...

Ngày tải lên: 13/08/2014, 11:22

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Báo cáo y học: "rogesterone in traumatic brain injury: time to move on to phase III trials" doc

Báo cáo y học: "rogesterone in traumatic brain injury: time to move on to phase III trials" doc

... in traumatic brain injury: a complex struggle against the nature of biology. Curr Opin Crit Care 2007, 13:134-142. 5. Wang KK, Larner SF, Robinson G, Hayes RL: Neuroprotection targets after traumatic ... [6-8]. Competing interests SMM is an investigator in the Traumatic Brain Injury Clinical Trials Network. JDK is a Principal Investigator in the Resusci- tation Outcomes Consortium. References 1. ... to clinical reality are vital to those of us seeking to expand our armamentarium of therapeutic options in the treatment of these injuries [6-8]. Competing interests SMM is an investigator in the...

Ngày tải lên: 13/08/2014, 11:22

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