Báo cáo y học: " Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia" ppt

... 8:8 http://www.clinicalproteomicsjournal.com/content/8/1/8 Page 7 of 12 REVIEW Open Access Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic ... maintenance therapy, clinical implementation Introduction Individualized medicine In individualized medicine, physicians seek to balance tre...

Ngày tải lên: 13/08/2014, 13:20

... cystic hygromas have mediastinal extensions [5]. Isolated intrathoracic cystic hygroma is a rare finding; less than 1% of all cystic hygromas are purely mediastinal in origin. In the majority of cases, ... heart. In young infants with larger pure mediastinal cystic hygromas, a varying degree of respiratory compromise is the most common presenting symptom, usually secondary to extr...

Ngày tải lên: 11/08/2014, 21:22

... central role of type I interferons (IFNs) driving innate immunity. Youinou and Pers [7] address the obvious abnormalities of other cytokines such as BAFF/BLyS, interleukin-17, and tumor necrosis ... immunopathogenesis of Sjögren syndrome. Sipsas and colleagues [4] explore the potential role of retroviruses in initiating or maintaining disease. Vitali [5] examines the diff erenc...

Ngày tải lên: 12/08/2014, 17:22

... performed by immunofluo- rescence and immunohistochemistry. Immunofluorescence detection Disclosure of secondary antibody binding was performed by incubation in 1:50 dilution of rhodamine-conjugated ... and the staining intensity increased with time post injection (Figures 4 and 5b). Aggrecan matrix staining within the vicinity of the injected cells was also observed 1 week follow...

Ngày tải lên: 09/08/2014, 01:22

... delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary ... performance in an area of interest We used the National Registry of Myocardial Infarction [65], a patient registry of patients treated with primary PCI for acute...

Ngày tải lên: 11/08/2014, 05:21

... accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Competing interests The authors declare that they have no competing interests. Authors' ... Collaboration Group. University of Zaragoza (Spain). PGR-1 Hot-Dog: a new rat model for the study of the experimentally-induced endometriosis in rats. Proceedings of t...

Ngày tải lên: 11/08/2014, 17:21

... body mass index, physical capability and dyspnea that can be part of such grading systems. This may lead to residual confound- ing. In evaluating the association between treatment and mortality ... University Hospital, Bergen, Nor- way; The Department of Respiratory Medicine, Tampere University Hospital, Tampere, Finland; The Department of Respiratory Medicine, Vifilstadir Universit...

Ngày tải lên: 12/08/2014, 16:20

... potently inhibits HIV-1 replication by inhibiting a late step in the proteolytic processing cascade of Gag by specifically blocking the cleavage of SP1 from the C-terminus of CA [10-12]. Inhibiting ... used to infect the TZM-bl indicator cell line. Infectivity was measured 48 h postinfection by determining levels of luciferase activity. Relative infectivity was calculated by...

Ngày tải lên: 12/08/2014, 23:23

... DNA). In PM-1 cells infected with NLΔSL1, syncytia were observed 14 days postinfection (p.i.) in one culture and 22 days p.i. in another, whereas NL4-3 infected cells showed syncytia by 7daysp.i.(datanotshown).Virusproductioninthe infected ... production of infectious virions, thereby redu- cing the overall infectivity of the virus. In support of this hypothesis, we found that...

Ngày tải lên: 13/08/2014, 01:20

... defined as a coordinated inspiratory- expiratory sequence manifest as a large burst of inspira- tory EMG activity immediately followed by a burst of expiratory ABD activity with an inspiratory-expiratory waveform ... committee of Jessenius Faculty of Medicine Commenius University and the State veterinary administration of Slovakia (N° 5492/1999-500 and 6708/03-220) or by the U...

Ngày tải lên: 13/08/2014, 08:20