Handbook of Experimental Pharmacology - Part 8 pdf

... (2001) Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation 103 :89 –95 Shand DG (1 983 ) Clinical pharmacology of the beta-blocking ... Distinct voltage-dependent regulation of a heart-delayed IK by protein kinases A and C. Am J Physiol 261:C1 081 –C1090 Experimental Therapy of Genetic Arrhythmias:Disease-Specifi...

Ngày tải lên: 13/08/2014, 12:20

... Res 22 :80 8 81 7 Neuvonen PJ, Elonen E, Vuorenmaa T, Laakso M (1 981 ) Prolonged Q-T interval and se- vere tachyarrh ythmias, common features of sotalol intoxication. Eur J Clin Pharmacol 20 :85 89 Numaguchi ... Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. J Physiol (Lond) 559 :83 5 84 8 Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M...

Ngày tải lên: 13/08/2014, 12:20

... Na (+) -Ca(2+) exchangers by 7- chloro-3,5-dihydro-5-phenyl-1H-4,1-benzothiazepine-2-one (CGP-37157). J Pharmacol Exp Ther 306:1050–1057 Paulus WJ, Goethals MA, Sys SU (1992) Failure of myocardial inactivation: ... Slaughter RS, King VF, Garcia ML (1 989 ) Inhibitors of sodium-calcium ex- change: identification and development of probes of transport activity. Biochim Biophys Acta 98...

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... the state -of- the-art analytical instruments, all sta s of both Department of Legal Medicine and Advanced Critical Care Medical Center discussed together on the selection of each type of instruments, ... third-party institution is unfortunately not available for quality assurance of analysis of toxic compounds or for assessment of analytical data [19]; the third-party insti...

Ngày tải lên: 26/01/2014, 18:20

... Dallas, TX 7539 0-9 111, USA Ege.Kavalali@UTSouthwestern.edu T.C. S ¨ udhof, K. Starke (eds.), Pharmacology of Neurotransmitter Release. 23 Handbook of Experimental Pharmacology 184 . c  Springer-Verlag ... intracellular chloride channels (ClC-3, -4 , -5 , -6 and -7 ) are widely expressed, but ClC-3 has a particularly high level of expression in the brain, and dis...

Ngày tải lên: 29/03/2014, 13:20

... sample of the Boston group (Herzog et al., 1 984 and Carlat et al., 1997) 26–42% of the eating-disordered males depicted them- selves as being homo- or bisexual. Only very few of the eating-disordered ... eating-disordered males quite frequently report teasing by peers. Sixty-four percent of bulimic males in the study of Herzog et al. (1 984 ) had a history of being overweight com...

Ngày tải lên: 10/08/2014, 20:21

... Figures and 11 Tables ISSN 017 1-2 004 ISBN-10 3-5 4 0-2 496 7-2 Springer Berlin Heidelberg New York ISBN-13 97 8- 3 -5 4 0-2 496 7-2 Springer Berlin Heidelberg New York Library of Congress Control Number: 2005925472 This ... Shiroshita-Takeshita, S. Nattel Experimental Therapy of Genetic Arrhythmias: Disease-SpecificPharmacology 267 S.G. Prio ri, C. Napolitano, M. Cerrone...

Ngày tải lên: 13/08/2014, 12:20

... 36:663–672 Burdon-Sanderson JS, Page FJM ( 187 9) On the time relations of the excitatory process in the ventricle of the heart of the frog. J Physiol (Lond) 2: 384 –435 Burdon-Sanderson JS, Page FJM ( 188 3) On ... 1 38: 279– 288 Purkinje JE ( 184 5) Mikroskopisch-neurologische Beobachtungen. Arch Anat Physiol Med II/III: 281 –295 Rosen MR, Reder RF (1 981 ) Does triggered activity ha...

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... that form part of the contact points with inner mouth blockers are present (Fig. 2a). The lack of the P-X-P sequence in the S6 domain of KCNH2 creates a large volume of the inner vestibule of the ... genetic basis of variability in drug respo nses. Nat Rev Drug Discov 1:37–44 Rosen MR, Wit AL (1 983 ) Electropharmacology of anti-arrhythmic drugs. Am Heart J 106 :82 9 83 9 Rose...

Ngày tải lên: 13/08/2014, 12:20

... potassium current IKs by (R )-2 -( 2,4-trifluoromethyl)-N-[2-oxo- 5- phenyl- 1-( 2,2,2-trifluoroethyl )-2 , 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]acetamide. J Med Chem 40: 386 5– 386 8 Sesti F, Tai KK, Goldstein ... isoforms of the mouse ether-a-go-go-related gene coassembleto form channelswithproperties similartothe rapidly activatingcomponent of the cardiac delayed rectifier K+...

Ngày tải lên: 13/08/2014, 12:20