Harper’s Illustrated Biochemistry - Part 2 pptx

Harper’s Illustrated Biochemistry - Part 2 pptx

Harper’s Illustrated Biochemistry - Part 2 pptx

... −− − 22 2 +→ + + ⋅ + Substrate A-H A-OH P450-A-H Fe 3 + P450 Fe 3 + P450-A-H Fe 2 + P450-A-H Fe 2 + O 2 O 2 CO P450-A-H Fe 2 + O 2 – 2Fe 2 S 2 3 + FADH 2 FADNADPH + H + 2H + e – e – H 2 O NADP + 2Fe 2 S 2 2 + NADPH-CYT ... hemolymph. 1 O- - D -Glucopyranosyl-(1 → 1 )- - D -glucopyranoside. HO H HOCH 2 H OH H H OH O H O- - D-Glucopyranosyl-(1 → 4 )-...

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Harper’s Illustrated Biochemistry - Part 5 pptx

Harper’s Illustrated Biochemistry - Part 5 pptx

... pyrrole) CH 2 NH 2 CH 2 CH 2 CO COOH HH CH 2 CH 2 H NH CO C COOH C C C CH CH 2 N H CH 2 CH 2 COOH CH 2 COOH NH 2 ALA DEHYDRATASE 2H 2 O ALA SYNTHASE CO 2 δ-Aminolevulinate (ALA)α-Amino-β-ketoadipate Pyridoxal phosphate Figure ... 29 7 HN 2 H 7 5 Formylglycinamidin e ribosyl-5-phosphate R- 5- P (VI) 3 6 ATP, Mg H 2 O H 2 O H 2 O 2 + Ring closure 7 R- 5-...

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Harper’s Illustrated Biochemistry - Part 3 pdf

Harper’s Illustrated Biochemistry - Part 3 pdf

... 1,6-bisphosphate Fructose 6-phosphate H 2 O P i GLUCONEOGENESIS GLYCOLYSIS Glycogen Glucose Pyruvate Citrate F-1,6-Pase PROTEIN PHOSPHATASE -2 Inactive F -2 , 6-Pase Active PFK -2 Active F -2 , 6-Pase Inactive PFK -2 P P i ADP Figure ... 6-phosphate H 2 O P i GLUCONEOGENESIS GLYCOLYSIS Glycogen Glucose Pyruvate Citrate F-1,6-Pase PROTEIN PHOSPHATASE -2 Inactive F -2 , 6-Pase Activ...

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Harper’s Illustrated Biochemistry - Part 6 potx

Harper’s Illustrated Biochemistry - Part 6 potx

... P i 4A 4B 4F 4E + 4G 4A= AUGCap (A) n ATP ATP ADP + P i eIF-5 1A 3 ++ P i + 2 22B 22 B GDP GTP 2 2B 2B Met Met 2 Ternary complex eIF-2C Ternary complex formation Met Cap (A) n P site A site 80S ... 11: 02 AM Page 355 386 / CHAPTER 39 HMGI-Y ATF -2 cJun NF-κB IRF(IRF3/7) HMG PRDIV PRDII NRDI HMG HMG HMG PRDI-III IRF3 HMGI HMGI HMGI HMGI ATF -2 cJun IRF7 NF-κB Figure 39–9. Formatio...

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Harper’s Illustrated Biochemistry - Part 7 ppsx

Harper’s Illustrated Biochemistry - Part 7 ppsx

... ENZYME ANGIOTENSINASES Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu-Leu (~400 more amino acids) Asp-Arg-Val-Tyr- I le-His-Pro-Phe-His-Leu Asp-Arg-Val-Tyr- I le-His-Pro-Phe Arg-Val-Tyr- I le-His-Pro-Phe Figure 42 14. ... α-Hydroxylase24-Hydroxylase HO HO 27 25 24 26 HO CH 2 CH 2 OH OH 7-Dehydrocholesterol 1 ,25 (OH) 2 -D 3 24 ,25 (OH) 2 -D 3 1 ,24 ,25 (OH) 3 -D 3 25 -Hydroxycholeca...

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Harper’s Illustrated Biochemistry - Part 9 pps

Harper’s Illustrated Biochemistry - Part 9 pps

... of F-actin–dependent activation of ATPase) Contraction activated by Ca 2+ Ca 2+ Direct effect of Ca 2+ 4Ca 2+ bind to TpC 4Ca 2+ bind to calmodulin Effect of protein-bound Ca 2+ TpC ⋅ 4Ca 2+ antagonizes ... “arrowheads.” (Courtesy of JA Spudich.) ATP-Myosin ADP-P i -Myosin Actin H 2 O Actin ATP ADP + P i Actin-Myosin Actin-Myosin ADP-P i Actin-Myosin ATP 1 2 3 4 5 Figure 49–...

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Get Set - Go!: Pupil''''s Book Starter part 2 pptx

Get Set - Go!: Pupil''''s Book Starter part 2 pptx

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Harper’s Illustrated Biochemistry Twenty-Eighth Edition_2 docx

Harper’s Illustrated Biochemistry Twenty-Eighth Edition_2 docx

... hydrolases, including α-neuraminidase, β-galactosidase, β-hexosaminidase, - and β-mannosidases, α-N-acetylgalactosaminidase, α-fucosidase, endo- β-N-acetyl- glucosaminidase, and aspartylglucosaminidase. ... transferase; ② α-glucosidase I; ③ α-glucosidase II; ④ endoplasmic reticulum α 1 , 2- mannosidase; I N-acetylglucosaminylphosphotransferase; II N-acetylglucosamine-1-phosphodiest...

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Harper’s Illustrated Biochemistry Twenty-Eighth Edition_1 ppt

Harper’s Illustrated Biochemistry Twenty-Eighth Edition_1 ppt

... well-ordered crystals. To establish appropriate Forkhead transcription factor DNA-bindingNLS Pr-Pr 6-Phosphofructo -2 - kinase/Fructose -2 , 6-bisphosphatase Reg RegCatalysis Pr-Pr RegCatalysis Pr-Pr Pr-Pr Catalysis Catalysis Phenylalanine ... bisphosphatase activities of 6-phosphofructo -2 - kinase/fructose- 2, 6-bisphosphatase are catalyzed by the N- and C-terminal proximate catalytic dom...

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harper's illustrated biochemistry - robert k. murray, darryl k. granner, peter a. mayes, victor w. rodwell

harper's illustrated biochemistry - robert k. murray, darryl k. granner, peter a. mayes, victor w. rodwell

... for O 2 than HbA. CARBONIC ANHYDRASE Hb • 4O 2 Hb • 2H + (buffer) 4O 2 4O 2 2H + + 2HCO 3 – 2HCO 3 – + 2H + 2H 2 CO 3 2CO 2 + 2H 2 O Exhaled LUNGS CARBONIC ANHYDRASE 2H 2 CO 3 2CO 2 + 2H 2 O Generated ... is hydro- phobic Hydroxylamine Asn-Gly o-Iodosobenzene Trp-X Mild acid Asp-Pro ch04.qxd 2/ 13 /20 03 2: 02 PM Page 26 2/ CHAPTER 1 disease can open up areas of cel...

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