Báo cáo khoa học: "Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients" pot
... pattern as in blood but surpris- ingly continued to increase throughout the study period in both burned and uninjured skin. It seems that insulin resistance con- tinues locally, in this case in the ... concentration in skin showed a tendency to increase, but to a lesser extent than lactate, during all study days in patients in uninjured skin (131 mmol/l [63 to 181]) and b...
Ngày tải lên: 13/08/2014, 03:20
... anti -in ammatory ⁄ antioxi- dant potential of these compounds by examining their scavenging effects on O 2 – from PMA-stimulated PMNs, with or without inhibition of NADPH oxidase as an index ... O 2 – -scavenging effects of the compound were found by eliminating MCLA-depen- dent CL. Arrows indicate the time at which MCLA or PMA was added. O 2 – was recorded for 15 min with a luminescence...
Ngày tải lên: 23/03/2014, 07:20
... histopathological lesions in the seminiferous tubules. There were thickening and multiple layering of the tubular endothelium, and the formation of many multinucleated giant cells in seminiferous tubules. ... 10 minutes and were stained by 5% Giemsa staining solution (in phosphate buffer, pH 6.8). The concentration of 50% cytotoxicity was determined by microscopic observation. Based on...
Ngày tải lên: 07/08/2014, 18:21
Tài liệu Báo cáo khoa học: Chromokinetics of metabolic pathways doc
... contains the known protein interactions. Using a variant of the methods described above, useful information about the regulatory functions of protein interactions can then be obtained. Such investigations ... experimental conditions in Table 1. This plane was then colored in place within the tetrahedron again by assigning a corresponding RGB value furnished by the spatial coordinates. In...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: Temperature and phosphate effects on allosteric phenomena of phosphofructokinase from a hibernating ground squirrel (Spermophilus lateralis) pptx
... In hibernators, the aci- dotic conditions found in muscle during hibernation can lead to an increase in histidine protonation and these effects may be translated into alterations in enzyme kinetics ... 4). Discussion A reduction in glycolytic rate occurs during hiberna- tion with the putative major site of inhibitory control being phosphofructokinase. Major physiological mani-...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid docx
... decrease in O 2 concentration in both the gas and liquid phases and the rapid increase in CO 2 concentration in both phases following the shift in benzoic acid concentration reflect a rapid increase in ... 72 h after the shift in benzoic acid concentration, the increase in OUR and the decrease in biomass concentration in the chemostat result in a strong and steady increas...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork docx
... (asterisks 2 and 3 in Fig. 2B) are highly conserved in the I domain of the RAD2 ⁄ XPG family, and are important in coordinating divalent metal ions to interact with an incoming nucleotide [21]. ... figure legends. Immunostainning of Drosophila embryos A polyclonal antibody against the DmGEN protein was raised in a rabbit using the purified recombinant DmGEN fragment (amino acid residues...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... with tachykinin neurokinin-1 receptors using [3-prolinomethionine 11] SP analogues. J. Biol. Chem. 274, 3770–23776. 40. Kenakin, T.P. & Morgan, P.H. (1989) Theoretical effects of single and ... the NK-1m binding site and potency to activate phospholipase C of b-amino acid- containing peptide analogues. Symbols are the experimental results obtained with data in Table 1. Dotted lines repre...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation pdf
... secondary kinetic isotope effects [19,27–29]. The existence of a gem secondary kinetic isotope effect has the effect of attenuating the rate of C-H bond-breaking, so in prin- ciple the intrinsic kinetic ... the intramolecular values in Table 1 are reasonable but should be considered lower estimates of the intrin- sic kinetic deuterium isotope effects. Intermolecular competitive kineti...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf
... TOP and neurolysin inhibitors [24] and a highly specific neurolysin inhibitor potentiated the neurotensin- induced antinociception of mice in the hot plate test when administrated intracerebroventricularly ... doi:10.1046/j.1432-1033.2002.03129.x Leu-enkephalin from the enkephalin-containing peptides [22], and the specific TOP inhibition increased Met-enke- phalin antinociception in rodents...
Ngày tải lên: 23/03/2014, 21:21