Báo cáo y học: " The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus" doc
Báo cáo y học: " The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus" doc
... ammatory cytokine production. is chronic produc-
tion of in ammatory cytokines and proteases may lead to
thinning of the plaque wall and eventual rupture, which
results in exposure of the blood ... secrete
in ammatory cytokines, reactive oxygen and nitrogen
species and proteases, all of which contribute to the
atherogenic phenotype in the blood vessel [14]....
Báo cáo y học: " Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus" doc
... of disease
activity, and that IL-17 blocking may offer a therapeutic target in SLE.
Introduction
Systemic lupus erythematosus (SLE or lupus) is an auto-
immune-mediated inflammatory disease of ... Puisieux A, Eliaou JF, Bonnefoy-Berard N: Interleukin 17 acts in
synergy with B cell-activating factor to influence B cell biology and the
pathophysiology of systemic lup...
Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf
... When the role of TNF and TNF inhibition in
systemic lupus erythematosus (SLE)–especially the latter two
effects–is examined, modulation of the immune (and auto-
immune) reactivity and pro-inflammatory ... thus
fostering autoimmunity. However, in SLE, both IFN-α and TNF
are highly increased and the levels of both of these cytokines
are associated with disease...
Báo cáo y học: " The impact of ADHD and conduct disorder in childhood on adult delinquency: A 30 years follow-up study using official crime records" potx
... behaviour in
adolescence.
During the last decades, there has been a growing
interest in the interplay between internalizing and exter-
nalizing problems, but there have been no clear findings
about the ... between
ADHD symptoms and later antisocial personality pro-
blems. Neither did they find that the combination of
internalizing and externalizing symptoms appeared to
a...
Báo cáo y học: "The renal metallothionein expression profile is altered in human lupus nephriti" doc
... profile in systemic lupus erythematosus
patients with nephritis.
Introduction
Systemic lupus erythematosus (SLE) is an immune-inflamma-
tory disorder characterized by multiorgan involvement and ... specimens. In the
remaining lupus nephritis biopsies, we noted the presence of
proximal tubules displaying low to absent epithelial MT-I+II
staining in combination with stro...
Báo cáo y học: "The Journal of Inflammation" docx
... required the
study of the immune system, in order to understand the
events involved in initiating and maintaining inflamma-
tory conditions. Today it is recognised that the underlying
genetics and ... apparent. However, the success of anti-TNFα
therapy in RA underlines the importance of understand-
ing/discovering the initial driver(s) of the inflammatory
res...
Báo cáo y học: " The role of inflammation in ICU-acquired weakness" pot
... stress or the interaction of oxidative
stress and pro -in ammatory biomarkers as risk factors
for myopathy in ICU patients [5]. Findings from this
study illustrate the challenges of translating ... insulin growth factor binding protein (IGFBP)-1);
serum osmolarity; medication use (norepinepherine,
dobu tamine, hydrocortisone, aminoglycosides, analgesics,
sedatives and neur...
Báo cáo y học: "The Geography of Chronic Obstructive Pulmonary Disease Across Time: California in 1993 and 1999"
... 84% of the
total direct cost of the disease. The impact of COPD on
the healthcare system may also be due to un-
der-diagnosis and treatment of COPD, suggesting the
need for improved early detection ... underpins the basis of probability theory
[18, 19]. Gotway and Young [17] outline a combination
of spatial smoothing and geostatistical upscaling or
aggregati...
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... phenylalanine was therefore
mutated to Ala, Leu, Trp or Tyr. These mutations may
in uence the shape and volume of the acyl binding pocket
and thereby alter the binding mode and affinity of the
enzyme ... the
enzyme for PAA and derivatives thereof, while maintaining
the hydrophobicity of the binding site.
To test the effect of the mutations on the specificity...
Báo cáo Y học: The evolution of monomeric and oligomeric bc-type crystallins potx
... recorded
only for the sequences encoding the interdomain linker
peptides and the N- and C-terminal extensions. These
findings certainly have an evolutionary significance.
In both b-andc-type crystallin ... crystallins [7,25,44–51].
The burying of the hydrophobic patches at the interdo-
main interfaces, intramolecular in the c-type structure,
intermolecular in the b-t...