Báo cáo y học: "Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathoge"nesis of the disease potx

... Autophagy activation was evaluated by quantifying the fluorescence intensity of LysoTracker™ Red staining of blood mononuclear cells. Mitophagy was confirmed by measuring citrate synthase activity and ... of autophagic genes and the elimination of dysfunctional mitochondria with mitophagy. Conclusions: These findings may support the role of oxidative stress an...

Ngày tải lên: 12/08/2014, 11:22

... function by binding to the bacteri al ribosome and inhibiting bacterial protein synthesis. The mito- chondrial protein synthesis machinery is in many ways similar to the prokaryotic machinery and as ... [179], i.e., the final electron acceptor of the mitochondrial respiratory chain. This property mainly determines the high toxicity of this compound. On the other hand,...

Ngày tải lên: 20/06/2014, 23:20

... proof -of- concept study to determine whether two of the cardinal signs of disease activity in arthritis (swelling and warmth) can be reliably quantified using existing three-dimen- sional (3D) and ... target. Following International Acad- emy of Clinical Thermology guidelines [9], subjects were asked to remove all jewelry and clothing covering the joints of interest an...

Ngày tải lên: 09/08/2014, 10:22

... complications of extracorporeal shock wave lithotripsy are perinephric bleeding and hypertension. Case presentation: We describe the case of a 31-year-old Asian man with an unusual case of hemoptysis and lung ... pulmonary complications, including pulmonary contusion [4], pulmonary edema [5] and hemoptysis in a child [6]. Here, we report an unusual case of hemoptysis followi...

Ngày tải lên: 11/08/2014, 03:21

... pulmonary symptoms. Physical examination showed diminished breath sounds in his left lung, accompanied by generalized wheezing. His blood pressure was 120/80 mm/Hg and his respiratory and heart ... including pulmonary contusion [4], pulmonary edema [5] and hemoptysis in a child [6]. Here, we report an unusual case of hemoptysis following ESWL. Case presentation A 31 -year-old As...

Ngày tải lên: 11/08/2014, 07:20

... contact with the criminal system, their defining fea- tures place them at high risk for aggression and violence [12]. Offenders with psychopathy typically begin their antisocial and criminal activities ... 100 and 155 during the last ten years [3]. The rates per capita have for decades been about double the rate of the most of the other West European democracies and tr...

Ngày tải lên: 11/08/2014, 17:20

... Laitinen and co-workers analyzed also the number of eosinophils and lymphocytes, but did not found any correlation between the amount of these inflammatory cells and the expression of Tn-C. In the ... positive bundles in the cytoplasm of cells, extracellular fibronec- tin-containing structures on the surface of the cell, and extracellular Tn-C in the...

Ngày tải lên: 12/08/2014, 13:22

... (by promoting beneficial body composition changes and reducing fatigue), inhibit progression of the disease (by reducing inflammation and increasing muscle mass and bone mineral density), and lead ... directly either the effects of hospitali- sation to quality of life, or the costs incurred as a result of it. On the other hand, the originality of the question,...

Ngày tải lên: 12/08/2014, 17:22

... explained by the disease of which the patients died. On the bas is of the CRYCO findings, recently issued clinical guidelines recommended the avoidance of hyperoncotic dextran, HE S, and albumin ... albu- min group from the CRYCO analysis. Several factors may limit the reliability and generalizab ility of the CRYCO results with respect to hyperoncotic albumin, na...

Ngày tải lên: 13/08/2014, 21:21

... constitutively expressed by cells of the monocyte lineage, rather than being part of the macrophage activation profile. No expression of Cathepsin S is seen in wounded or unwounded skin of the macrophageless ... to the migratory machinery of leukocytes in vivo, informing us, for example, which chemokines might be key attractive cues by revealing which of the chem...

Ngày tải lên: 14/08/2014, 14:21