... regulated by distinct kinasepathways independent of inhibitor of κB kinase (IKK). Here, we examine the role of protein kinaseC isoforms and janus activated kinase 2 (JAK2) activation in NF-κB ... expression during such inflammatory responses. Arange of inflammatory stimuli, including endotoxin [1,2]and cytokines [3], produce activation and nuclear translo-cation of NFκB following rapid degradation ... previously shown to inhibit the p68 MAPkinase family [22]. For the purpose of specific inhibition of PKC translocation, the following MALY-TAT linkedpeptides (kindly supplied by Dr M. Lindsay, AstraZeneca,Charnwood,...