báo cáo khoa học: " Salivary a-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells" docx

... time that salivary a-amylase exhibits in vitro antiproliferative effects in primary rat mammary epithelial cells and human breast tumor cells. On the one hand the effects on healthy rat breast cells indicate ... al.: Salivary a-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells...

Ngày tải lên: 10/08/2014, 10:21

... dissociation/unfold- ing mechanism of the protein remains to be determined. In this study, we examined the M r of the protein after equilibration in various denaturing concentrations of GndHCl. Figure ... weight of monomeric d 2 -crystallin. Multistep unfolding of monomeric d 2 -crystallin Further increases in GdnHCl concentration induced unfold- ing of the dissociated monom...

Ngày tải lên: 08/03/2014, 08:20

... con- ditions of low glucose concentration, translation of proinsulin in pancreatic b -cells is repressed by activa- tion of PERK, and the UPR controls the terminal dif- ferentiation of B -cells into antibody-secreting ... pro- tein of 295 amino acids with an N-terminal bZIP DNA-binding domain, a putative transmembrane domain, and a 56-amino-acid small C-terminal domain (Fig....

Ngày tải lên: 16/03/2014, 11:20

... involving cellular thiols and disulfides [1,5–7]. On the other hand, the NAD(P)H/ NAD(P) + and SH/S-S ratios are intimately related to the cellular level of ROS. Reduced pyridine nucleotides and thiols ... number of cellular systems cooperate in redox regulation, providing metabolic responses according to changes in the oxidation (or reduction) of the redox active components o...

Ngày tải lên: 17/03/2014, 09:20

... defects in flavin cofactor homeostasis and the function of mitochondrial FAD-binding enzymes. Correlation of these has been demonstrated in human pathologies, including deficiencies of the flavoprotein ... Detection of Sdh1-HAp in cellular extracts from WT-HA and flx1D-HA cells incubated in the absence or presence of the uncoupler FCCP. Glycerol-grown WT-HA (A) and flx1...

Ngày tải lên: 23/03/2014, 07:20

... the C-terminal peptide, composed of 13 amino acids, was not important in substrate recogni- tion, but was primarily involved in protein cofactor binding. Thus, 13 C-terminal amino acids of yeast SerRS ... involved in cell wall synthesis [29], and heat shock protein 90 interacts with human glutamyl-prolyl-tRNA synthetase and medi- ates protein–protein interactions during the...

Ngày tải lên: 23/03/2014, 09:20

... EspA⁄ B ⁄ D and a-catenin, facili- tates the delivery of effector proteins into host cells [16]. Although there is information available concerning the roles and structural properties of EspA filaments, to ... protein folding? Trends Biochem Sci 22, 6–10. 32 Kuwajima K (1989) The molten globule state as a clue for understanding the folding and cooperativity of glob- ular-protein...

Ngày tải lên: 30/03/2014, 16:20

... report in the literature of an intracranial meningeal metastasis of Merkel cell carcinoma treated with gamma knife and of intraspinal intradural metastases of Merkel cell carcinoma. Despite good initial ... recurrence and occurrence of new metastases are common in Merkel cell carcinoma. Introduction Merkel cell carcinoma (MCC) is a rare malignant neo- plasm of the...

Ngày tải lên: 11/08/2014, 03:20

... on individual decision-making in scheduling ROEs. In the second arm, the intervention focuses on monitoring and decision-making regarding prophylactic removal versus retention of MIM. Groups of ... after the meeting. The main outcome measure for the ROE intervention arm is the use and appropriateness of individualised risk assessment in assigning recall intervals, and for t...

Ngày tải lên: 11/08/2014, 05:22

... Mutations of DOF1 and DOF2 (mDOF(1+2)::GUS), DOF1 and DOF3 (mDOF(1+3)::GUS) or DOF1 and DOF4 (mDOF(1+4)::GUS) completely inactivated the minimal promoter, as GUS expression was abolished in all ... sufficient to induce 24 Figure 3 - Role of DOF-binding sites in the minimal promoter in driving GUS activity in guard cells A, Schematic diagrams of constructs -262::G...

Ngày tải lên: 11/08/2014, 11:21