A–Z of Haematology - part 6 pps

... composed of repeats of branched poly-N-acetyllactosaminoglycan, on adult red cells, produced by the action of -1 , 6- N acetylglucosaminyl transferase on i antigen I-branching ββ -1 , 6- N acetylglucosaminyl transferase an ... Zav a , Hc a ) HPA-6w HPA-6bw (previously Ca a , Tu a ) IIIa HPA-7w HPA-7bw (previously Mo) IIIa HPA-8w HPA-8bw (previously Sr a ) IIIa HPA-9w HPA-9bw (prev...

Ngày tải lên: 10/08/2014, 08:20

... transformation of myelopro- liferative disorders, forming AML 1- EAP, AML1-EVI1 and AML-MDS1 • part of ETV6 to form a fusion gene, ETV6-AML1 (TEL-AML1), detected in about 30% of cases of acute lymph- oblastic ... locus) -3 -N-acetyl D galactosylaminyltransferase (encoded by A 1 allele* at the ABO locus) AB (b) Locus Allele Transferase FUT1 ABO H h A B O -2 -L-fucosyltrans...

Ngày tải lên: 10/08/2014, 08:20

... with t(3;4)(q27;p13) •a SRP20-BCL6 fusion gene in non- Hodgkin’s lymphoma with t(3 ;6) (q27;p21) • an H4-BCL6 fusion gene in non- Hodgkin’s lymphoma with t(3 ;6) (q27;p21) • an IKAROS-BCL6 fusion gene in non- Hodgkin’s ... chromosome num- ber that is not 46 nor a multiple nor half of 46 aneuploidy presence of a clone of cells with a number of chromosomes which is not 46 nor a multi...

Ngày tải lên: 10/08/2014, 08:20

... CD60b and CD60c CD60a a glycolipid, GD3 CD60b a glycolipid, 9-O-acetyl-GD3 CD60c a glycoclipid, 7-O-acetyl-GD3 CD61 a surface membrane glycoprotein, the β3 integrin chain, GpIIIa; part of the GpIIb/IIIa ... condition from non-Hodgkin’s lymphoma; ex- pressed on the blast cells of some cases of acute lymphoblastic leukaemia CD80 ligand of CD28 and CD152; co- regulator, with CD 86, o...

Ngày tải lên: 10/08/2014, 08:20

... ex- pression in about a third of cases of acute leukaemia and chronic granulocytic leuk- aemia, particularly in blast crisis DDAVP 1-deamino -6 - D-arginine vaso- pressin, desmopressin acetate D-dimer ... deletion of part of a chromo- some, either part of the long arm or part of the short arm (del) (ii) deletion of a DNA sequence with the regions on either side being rejoi...

Ngày tải lên: 10/08/2014, 08:20

... 113 Glucose ATP ADP Hexokinase Glucose -6 - phosphate Fructose -6 - phosphate Fructose-1 , 6- diphosphate Glyceraldehyde- 3-phosphate 1,3-biphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate Phosphoenolpyruvate Pyruvate Lactate Dihydroxyacetone phosphate Haemoglobin Methaemoglobin ATP ADP Glucosephosphate ... is mutated in about 10% of cases of multiple myeloma and in about 10% of...

Ngày tải lên: 10/08/2014, 08:20

... central part of a bone composed of an anastomosing network of trabecular or cancellous bone (ii) the central part of the kidney (iii) the central part of a lymph node (iv) the central part of the ... molecules (HLA-A, HLA- B and HLA-C) are concerned with recog- nition of antigens expressed on altered body cells and class II molecules (HLA- DP, HLA-DQ and HLA-DR) with the...

Ngày tải lên: 10/08/2014, 08:21

... 210 Table 16 Some of the genetic causes of severe combined immunodeficiency. Defect Deficiency of Janus-associated kinase 3 Deficiency of common γ chain of receptors for IL-2, IL-4, IL-7, IL-9 and ... rearrange- ment of the regions of an immunoglo- bulin or T-cell receptor gene (see Fig. 46, p. 135) red cell an erythrocyte, a non-nucleated cell of the peripheral blood the mai...

Ngày tải lên: 10/08/2014, 08:21

... in blast cells of 88% of cases of acute lym- phoblastic leukaemia and 97% of cases of acute myeloid leukaemia. Wolman’s disease an inherited meta- bolic disorder, a juvenile form of choles- terol ester ... patients of any blood group, i.e. an O Rh D-negative donor (without a high titre of anti-A or anti-B antibodies) universal precautions an approach to prevention of transm...

Ngày tải lên: 10/08/2014, 08:21

... in 861 , Arch- bishop Hincmar of Reims took over the writing of the Annals of St-Bertin, until his own death in 882. Like the Royal Frankish Annals and the Annals of Fulda, the An- nals of St-Bertin ... of Bremen’s History of the Arch- bishops of Hamburg-Bremen. Ansgar, a monk from Corvey Abbey, Westphalia (present-day Ger- many), was first sent to Scandinavia by Louis the Pio...

Ngày tải lên: 02/07/2014, 04:21