A–Z of Haematology - part 6 pps
A–Z of Haematology - part 6 pps
... composed of repeats of
branched poly-N-acetyllactosaminoglycan,
on adult red cells, produced by the action
of -1 , 6- N acetylglucosaminyl transferase
on i antigen
I-branching
ββ
-1 , 6- N acetylglucosaminyl
transferase
an ... Zav
a
, Hc
a
)
HPA-6w HPA-6bw (previously Ca
a
, Tu
a
) IIIa
HPA-7w HPA-7bw (previously Mo) IIIa
HPA-8w HPA-8bw (previously Sr
a
) IIIa
HPA-9w HPA-9bw (prev...
A–Z of Haematology - part 1 pptx
... transformation of myelopro-
liferative disorders, forming AML 1-
EAP, AML1-EVI1 and AML-MDS1
• part of ETV6 to form a fusion gene,
ETV6-AML1 (TEL-AML1), detected
in about 30% of cases of acute lymph-
oblastic ... locus)
-3 -N-acetyl D
galactosylaminyltransferase
(encoded by
A
1
allele* at the
ABO locus)
AB
(b)
Locus Allele Transferase
FUT1
ABO
H
h
A
B
O
-2 -L-fucosyltrans...
A–Z of Haematology - part 2 docx
... with
t(3;4)(q27;p13)
•a SRP20-BCL6 fusion gene in non-
Hodgkin’s lymphoma with t(3 ;6) (q27;p21)
• an H4-BCL6 fusion gene in non-
Hodgkin’s lymphoma with t(3 ;6) (q27;p21)
• an IKAROS-BCL6 fusion gene in non-
Hodgkin’s ... chromosome num-
ber that is not 46 nor a multiple nor half
of 46
aneuploidy presence of a clone of cells
with a number of chromosomes which is
not 46 nor a multi...
A–Z of Haematology - part 3 pdf
... CD60b and CD60c
CD60a a glycolipid, GD3
CD60b a glycolipid, 9-O-acetyl-GD3
CD60c a glycoclipid, 7-O-acetyl-GD3
CD61 a surface membrane glycoprotein,
the β3 integrin chain, GpIIIa; part of
the GpIIb/IIIa ... condition
from non-Hodgkin’s lymphoma; ex-
pressed on the blast cells of some cases
of acute lymphoblastic leukaemia
CD80 ligand of CD28 and CD152; co-
regulator, with CD 86, o...
A–Z of Haematology - part 4 ppt
... ex-
pression in about a third of cases of acute
leukaemia and chronic granulocytic leuk-
aemia, particularly in blast crisis
DDAVP 1-deamino -6 - D-arginine vaso-
pressin, desmopressin acetate
D-dimer ... deletion of part of a chromo-
some, either part of the long arm or part
of the short arm (del) (ii) deletion of a
DNA sequence with the regions on either
side being rejoi...
A–Z of Haematology - part 5 potx
... 113
Glucose
ATP
ADP
Hexokinase
Glucose -6 - phosphate
Fructose -6 - phosphate
Fructose-1 , 6- diphosphate
Glyceraldehyde-
3-phosphate
1,3-biphosphoglycerate
3-phosphoglycerate
2-phosphoglycerate
Phosphoenolpyruvate
Pyruvate
Lactate
Dihydroxyacetone
phosphate
Haemoglobin
Methaemoglobin
ATP
ADP
Glucosephosphate ... is mutated in about
10% of cases of multiple myeloma and
in about 10% of...
A–Z of Haematology - part 7 ppt
... central part of a bone
composed of an anastomosing network
of trabecular or cancellous bone (ii) the
central part of the kidney (iii) the central
part of a lymph node (iv) the central part
of the ... molecules (HLA-A, HLA-
B and HLA-C) are concerned with recog-
nition of antigens expressed on altered
body cells and class II molecules (HLA-
DP, HLA-DQ and HLA-DR) with the...
A–Z of Haematology - part 9 potx
... 210
Table 16 Some of the genetic causes of severe combined immunodeficiency.
Defect
Deficiency of Janus-associated
kinase 3
Deficiency of common γ chain
of receptors for IL-2, IL-4, IL-7,
IL-9 and ... rearrange-
ment of the regions of an immunoglo-
bulin or T-cell receptor gene (see Fig. 46,
p. 135)
red cell an erythrocyte, a non-nucleated
cell of the peripheral blood the mai...
A–Z of Haematology - part 10 doc
... in
blast cells of 88% of cases of acute lym-
phoblastic leukaemia and 97% of cases of
acute myeloid leukaemia.
Wolman’s disease an inherited meta-
bolic disorder, a juvenile form of choles-
terol ester ... patients of
any blood group, i.e. an O Rh D-negative
donor (without a high titre of anti-A or
anti-B antibodies)
universal precautions an approach
to prevention of transm...
The A to Z of the Vikings 6 pps
... in 861 , Arch-
bishop Hincmar of Reims took over the writing of the Annals of
St-Bertin, until his own death in 882.
Like the Royal Frankish Annals and the Annals of Fulda, the An-
nals of St-Bertin ... of Bremen’s History of the Arch-
bishops of Hamburg-Bremen.
Ansgar, a monk from Corvey Abbey, Westphalia (present-day Ger-
many), was first sent to Scandinavia by Louis the Pio...
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