In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles pptx
... cited. Research In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC virus-like particles Meng-Ing Chou †1 , Yu-Fan Hsieh †2 , Meilin Wang 3 , Jinghua Tsai Chang 4 , Deching Chang 5 , ... 10.1186/1423-0127-17-51 Cite this article as: Chou et al., In vitro and in vivo targeted delivery of IL-10 interfering RNA by JC viru...
Ngày tải lên: 10/08/2014, 05:21
... to recruit and activate Rad17 complexes for checkpoint signaling in vivo. It may func- tion in the sensing of DNA damage [22]. In contrast with the intensive study of RPA in ani- mals and yeast, ... RPA ssDNA-binding domains, DBD-A and DBD-B, located within the central region, and a third, DBD-C, in the C-terminal region. DBD-A and DBD-B are the most important regions...
Ngày tải lên: 07/03/2014, 21:20
... accessible, presumably by disrupting protein–protein interactions within PSI, or by altering the conformation of the loop. His-tags were employed in a topological study of the major light harvesting chlorophyll ... 386 and 387, or at the extreme C-terminus of PSI-G (Fig. 1). These cassettes were both cloned into binary vectors under the control of the 35S promoter and termin...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Structural studies of the capsular polysaccharide and lipopolysaccharide O-antigen of Aeromonas salmonicida strain 80204-1 produced under in vitro and in vivo growth conditions docx
... O-chain containing L -rhamnose, 2-amino-2-deoxy- D -mannose and D -glucose [11], confirming that the novel CPS and O-chain polysaccharide were produced during the 72-h in vivo culture p eriod. In ... he structures of both CPS and O-chain polysaccharide were distinct from the previously reported O-chain polysacchar- ide of A. salmonicida produced in TSB and consisting of L...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: In vitro and in vivo self-cleavage of Streptococcus pneumoniae signal peptidase I pot
... pneumoniae SPase I For in vitro self-cleavage of S. pneumoniae SPase I in the presence of phospholipid, 20 lL of reaction containing 5 lg of purified SPase I was incubated in 37 °Cfor2hin 20m M Tris/HCl ... visualized protein bands on the membrane were excised and the N-terminal amino acid sequence of each protein was determined by automated Edman degradation. Cleavage o...
Ngày tải lên: 23/03/2014, 21:21
Báo cáo khóa học: Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo pot
... assay, saturable and carbohydrate-dependent binding was measured, and the resulting Scatchard plots gave straight lines indicating the presence of a single class of binding sites in each case (not shown). ... cell lines of diverse histogenetic origin. The median signal of binding of the fluorescent probe is given as extent of carbohydrate-ligand-dependent binding by subtrac...
Ngày tải lên: 30/03/2014, 13:20
Báo cáo hóa học: " N-methylisatin-beta-thiosemicarbazone derivative (SCH 16) is an inhibitor of Japanese encephalitis virus infection in vitro and in vivo" ppt
... reports describing the in vitro inhibitory effect of compounds such as ribavirin, mycophenolic acid, imino sugars, inhibitors of serine protease, RNA interference and non-steroidal anti-inflammatory ... 100% inhibition of viral plaques were evaluated by in vitro experiments detailed below. Determining kinetics of JEV replication in PS cells A 24 well plate containing s...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Inhibition of foot-and-mouth disease virus replication in vitro and in vivo by small interfering RNA" pot
... Central Page 1 of 6 (page number not for citation purposes) Virology Journal Open Access Short report Inhibition of foot -and- mouth disease virus replication in vitro and in vivo by small interfering RNA Wang ... small interfering RNA (siRNA) targeting homogenous 3D and 2B1 regions of 7 serotypes of FMDV were prepared and 2 siRNA-expression vectors, pSi-FMD2...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt
... Effects of active immunization of sheep against an amino terminal peptide of the inhibin αC subunit on intrafollicular levels of activin A, inhibin A and follistatin. Journal of Endocrinol- ogy ... for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học: " In vitro and in vivo pre-clinical analysis of a F(ab’)2 fragment of panitumumab for molecular imaging and therapy of HER1-positive cancers" pot
... MW: A new and convenient method for purification of Y-86 using a Sr(II) selective resin and comparison of biodistribution of Y-86 and In- 111 labeled Herceptin (TM). Nuclear Medicine and Biology ... in vivo and in vitro properties of the intact panitu- mumab mAb has been previously described by Ray et al. [25] which included imaging by planar g-scintigraphy. The...
Ngày tải lên: 21/06/2014, 02:20