ALZHEIMER''''''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 4 pps
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 4 pps
... disease. Neu-
rolog 3
42 , 63 1-6 39.
Auld, D. S., Kar, S., and Quirion, R. (1998)./3-amyloid peptides as direct cholinergic neuro-
modulators: A missing link?
Trends Neurosci.
21, 4 3 -4 9.
Ball, ... Predominance of A/3 and association of Aft40 with cored plaques.
Am.J. Pathol.
148 , 25 9-2 65.
Gahtan, E., and Overmier, J. B. (1999). Inflammatory pathogenesis in Alz...
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 1 doc
... performed. Both Lopez and colleagues (1990) and Kukall and col-
leagues (1990) used four raters to evaluate the NINCDS-ADRDA criteria.
Using cases with dementia (AD and non-AD) and nondemented controls, ...
1997b). However, the
ALZHEIMER'S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS
Jillian J. Kril I
Centre for Education and Research on Ageing, Concord Hospital
D...
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 2 doc
... mainly
A/3 1-3 9 /40 or sometimes A/3 1 -4 2 /43 (Haas, 1996; Neve and Robakis, 1998;
Storey and Cappai, 1999; Wilson
et al.,
1999; Coughlan and Breen, 2000;
Gandy and Petanceska, 2000). These peptides ... A/3 1 -4 0 and A/3 1 -4 2 /43 has enabled the evo-
lution and composition of plaques to be systematically studied (Iwatsubo
et al.,
1996; Dickson, 1997). The result...
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 3 pptx
... into the pathogenesis of AD. To date, three genes have been iden-
tified. These are APP mutations on chromosome 21, presenilin-1 (PS-1)
mutations on chromosome 14, and presenilin-2 (PS-2) mutations ... of e2, e3, and e4, and the presence
of the e4 allele has been found to increase the risk ofAD (Katzman, 19 94;
Strittmatter and Roses, 1995). ApoE is involved in lipid transport...
ALZHEIMER''''S DISEASE: ITS DIAGNOSIS AND PATHOGENESIS - PART 5 doc
... V. M Y, and Trojanowski,J. Q. (1996). Full-length
amyloid-fl( 1 -4 2 (43 )) and amino-terminally modified and truncated amyloid-f 142 (43 ) de-
posit in diffuse plaques. Am.J. Pathol. 149 , 182 3-1 830. ... Winblad, B., and Backman, L. (2000). The course of
cognitive impairment in preclinical Alzheimer disease: Three- and 6-year follow-up of a
population-based sample. Arch....
quality of life of alzheimer’s disease patients, caregivers and evaluating the effectiveness of thenonpharmacologicalinterventions
... instability
-0 .16 - 0.10
Aberrant Motor Behavior
-0 .09 -0 . 14
Night-time Behavior
-0 .33* -0 . 24*
Appetite/Eating Changes
-0 .13 -0 .00
Severity of NPI -0 .17 -0 .31*
Discruption of NPI
-0 .20* -0 .32* ... 8.39
45 - 54 years(n = 24) 44 .45 9.21 37.68 10.32
55 - 64 years(n = 16) 45 .38 8.72 37.31 12.76
X
X
X
X
X
16
Discruption NP...
Spinal Disorders: Fundamentals of Diagnosis and Treatment Part 4 docx
... anatomical drawings
and therefore his anatomical discoveries remained unknown for centuries.
Andreas Vesalius
(15 14 15 64) is the founder
of modern spinal anatomy
Andreas Vesalius (15 14 15 64) broke with ... (Cont.)
c Andreas Vesalius (15 14 15 64) . d Josias Weitbrecht’s (1702 – 1 747 ) Syndesmologia (1 742 ) precisely described the spinal
ligaments.
During the Middle Ages, no progress w...
Spinal Disorders: Fundamentals of Diagnosis and Treatment Part 16 pps
... afferent fibers and
plays a pivotal role in the spinal mechanisms of nociceptive transmission [9].
Synaptically released glutamate acts on kainate and AMPA ( -amino-3-hydroxy-
5-methyl -4 - isoxazolepropionic ... potential channels, MDEG mamma-
lian degenerin channel, P2X ATP-gated ion channel).
b Nociceptive transmission (AMPA -amino-3-hydroxy-5-methyl- 4-
isoxazolepropionic acid rece...
Spinal Disorders: Fundamentals of Diagnosis and Treatment Part 24 ppsx
... position
left/right rotation (normal: 40 °–0 40 °) in extended position
left/side bedding (normal: 40 °–0 40 °)
Cervical spine motion is
examined with active and
passive motion and against
resistance
In flexion, ... profile (hypo-/hyperkyphosis/lordosis)
muscle atrophies
level of shoulders
waist asymmetries and pelvic rotation
level of pelvis (in standing and flexed position)
rib/lu...
Từ khóa:
- alzheimer s disease education and referral center
- alzheimer s disease and related disorders
- alzheimer s disease mild cognitive impairment and clinically unimpaired subjects
- alzheimer s disease education and referr
- alzheimer s disease and other dementias
- rational therapeutics for alzheimer s disease and other dementias
- emotion and behavior in alzheimer s disease and other dementias