Báo cáo khoa học: "Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy" pot

... patients with acute toxicity and without it. Those genes were gathered in 4 significant pathways. We could not identify a set of genes that segregates patients with and without late toxicity. In conclusion, ... NA, Haveman J, Klein B, Turesson I, Vrieling H, Giphart-Gassler M: Analysis of gene expression using gene sets discriminates cancer patients with and witho...

Ngày tải lên: 09/08/2014, 09:22

... patients seen at the Instituto Nacional de Cancerología (INCan: a cancer- referral teach- ing hospital for adult patients, located in Mexico City) are stage IIB-IIIB, locally advanced breast cancer ... radiation-neumonitis frequency in patients with lung cancer treated with radiotherapy combined with gemcitabine [26,27], none of enrolled patients developed severe...

Ngày tải lên: 09/08/2014, 10:20

... well as in the adjuvant set- ting in colon cancers [8-14]. Furthermore, capecitabine has been investigated in various protocols for rectal and other gastro intestinal cancers in combinatio n ... Capecitabine Colorectal Cancer Study Group, et al: First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorou...

Ngày tải lên: 09/08/2014, 09:21

... hot spots in the majority of our cases, indicating additional factors determining normal tissue tolerance in IMRT. With respect to future proceeding, mild dose escalation limited to the GTV in patients ... sparing in patients with head-and-neck cancers receiving intensity- modulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys 2001, 49:...

Ngày tải lên: 09/08/2014, 10:20

... conducted semi-structured interviews with 34 breast cancer patients and 14 health professionals to further determine the information needs that breast cancer patients had before, during and after their ... regard- ing radiotherapy and radiation in patients receiving radio- therapy: a qualitative study. Eur J Cancer Care 1998, 7:103-112. 3. Long L: Being informed: undergoin...

Ngày tải lên: 09/08/2014, 10:21

... (VEGF) is associated with macrophage cell in l- tration in inflammation. Both VEGF and macrophage cells play a critical role in inflammatory processes including synovial joint in ammation [1–3], ... to VEGF gene expression in activated macrophage cells. Abbreviations AURE, adenosine-uridine-rich element; CAURE, cytidine-adenosine-uridine-rich element; CSD ⁄ PTB, cold shock domain...

Ngày tải lên: 07/03/2014, 12:20

... deter- mined in vitro using naringenin chalcone as the sub- strate. As shown in Fig. 8, the recombinant PfCHI1 protein could stereospecifically convert naringenin chalcone to (2S)-naringenin, whereas ... Vitis vinifera CHI (X75963). The deduced amino acid sequence of PfCHI1 exhibited 70% identity with that from V. vinifera. PfCHI1 (2S)-Naringenin (2S)-Naringenin Naringenin chalcone (2R)-...

Ngày tải lên: 23/03/2014, 07:20

... (2002) New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism. Oncogene 21, 8293–8301. Zonal gene expression in mouse liver A. Braeuning et al. 5060 FEBS Journal ... controlling mRNA stability are important fac- tors determining their zonal expression in liver. In addition, we found that several other genes with unknown localization in...

Ngày tải lên: 23/03/2014, 10:20

... is r 70 -dependent in R. capsulatus [1]. This is in line with the observation that the putative r 54 interaction sites within the HupR ⁄ HoxA proteins are well conserved in T. roseopersicina, Ra. eutropha ... acces- sion number L05081) containing the erythromycin resist- ance gene was inserted (pHRIMER2). For insertion mutagenesis of the rpoN gene, the 1618 bp PCR fragment obtained...

Ngày tải lên: 16/03/2014, 23:20

... different in comparison with those of vertebrate trypsins, and also they are important for inhibitor binding [8]. The phenylalanine and Ile resi- dues in crayfish Loop37 interact with the C-terminal segment ... and 226, chymotrypsin numbering) in bovine and all other crustacean trypsins; (B) predicted disulfide bridges in lobster trypsins; (C) calcium-binding site configuration in...

Ngày tải lên: 23/03/2014, 03:20