Báo cáo y học: "Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages" ppt

... 2 Characterization of the regions of SRP54 recognized by the human autoantibodiesCharacterization of the regions of SRP54 recognized by the human autoantibodies. (a) Summary of the immunoprecipitation of ... retardation [3,7], while the SRP 19 kDa protein facil- itates the binding of the 54 kDa subunit of the signal recogni- tion particle (SRP54)...

Ngày tải lên: 09/08/2014, 07:20

... included in one of the incuba- tion mixtures in case of an enzyme-catalyzed hydrolysis of the 17α furoate moiety or of the 17β S-fluoromethyl-car- bothioate group. Neither did we determine the resulting metabolites ... period of 24 hours at an incubation temperature of 37°C (Figure 3). The incubations were performed in the presence and absence of the esterase inh...

Ngày tải lên: 12/08/2014, 15:21

... predominantly the tunica intima consisting of the endothelial layer and the basement membrane, and αSMA (e, f) staining predominantly the tunica media consisting of the muscular layer of the arteriole ... rate of proliferation of the IPFP-derived cells in monolayer culture was significantly increased by FGF-2. A comparison of their proliferation rate with other stu...

Ngày tải lên: 09/08/2014, 10:23

... whereas the 26 to 28 -kDa polypeptides (together < 35% of the total protein) represent the unglycosylated and glycosylated form of the so-called CalsepRRP [14]. N-terminal sequencing of the 55 -kDa ... soybean b-amylase (Cys82, Cys97, Cys208 and Cys343). On the analogy of the soybean b-amylase, the active site of the C. sepium b-amylase most probably consists...

Ngày tải lên: 22/02/2014, 07:20

... borohydride [11±13] or directly by mass spect- rometry [14]. Alternatively the mixed anhydride interme- diates can be detected by the formation of stable derivatives of the catalytic glutamate ... out at the c oenzyme A thiol ester level rather than using the free carboxylates. A critical step in the reductive branch of this pathway is the activation of (R)-lactate as...

Ngày tải lên: 17/03/2014, 17:20

... seemed that the fourth protein copurified with the diol dehydratase does not belong to the dehydratase complex. Characterization of the diol dehydratase The molecular mass of the native dehydratase ... m M for glycerol. The enzyme required the adenosylcobalamin coenzyme for catalytic activity and the K m for the cofactor was 8 l M . Inactivation of the enzyme was...

Ngày tải lên: 23/03/2014, 21:20

... University of Athens "Attikon" General Hospital, Athens, Greece, 2 Office of Preventive Mental Health, Hellenic Navy, Skaramangas, Greece, 3 Department of Psychology, University of Athens, ... problems of the community; and thus stress the need for the existence of structures in the Hellenic Navy that can investigate the extent and nature of such prob- lem...

Ngày tải lên: 08/08/2014, 21:20

... in some of the parameters, they remained within the normal lab- oratory range. Statistical analyses of these parameters did not identify any statstically significant changes. Similarly, haemato- logical ... terms of reducing pain and improving the physical ability of OA patients. A novel aspect of the present study is its evaluation of the effect of 5-Loxin ® treatment...

Ngày tải lên: 09/08/2014, 10:23

... Downregulation of Ath5. Group 3 genes: Ndrg3 and Islet-2 may prevent premature downregulation of Ath5. Expression of Ath5 is downregulated by signals through Idax and the regulatory activity of RBPMS2, ... validates their role in RGC differentiation We complemented the characterization of candidate regula- tors by testing in vivo the activity of members of each of th...

Ngày tải lên: 09/08/2014, 20:20

... with leucoderma by the tribes of Kerala [60]. The Mompa of Arunachal use the fat of the crow in cases of smallpox and malaria [27]. Members of the Nyishi and Galo tribes use the gall bladder of the mithun ... through the consumption of whole frog bodies, the amphibian’ s flesh, or its skin alone [49,60]. The fat of the python also plays a role in the tr...

Ngày tải lên: 10/08/2014, 09:21