báo cáo khoa học: "Double primary malignancies associated with colon Cancer in patients with Situs Inversus Totalis: Two Case Reports" pptx
Báo cáo khoa học: Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases pptx
... cysta- tin B. (C) Zoom -in view of the interactions of papain with loop L4 of chagasin and the N-terminal segment of cystatin B. (D) Zoom -in view of the interactions of papain with loop L2 of chagasin ... contact with the main-chain N atom of G68, and the main-chain nitrogen of G66 of chagasin forms a water-mediated A B C D Fig. 2. Interactions of chagasin and cystatin B with papai...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Paralog of the formylglycine-generating enzyme – retention in the endoplasmic reticulum by canonical and noncanonical signals pptx
... ER proteins can be found. In fact, not a single human PGEL ER protein, apart from pFGE, and only one human protein with an N-terminal signal peptide and an SGEL C-terminus (endonuclease domain-containing protein ... (see Fig. 3). C-terminal FGE regions encoded in the last exon are aligned. Species with an FGE C-terminus containing a terminal KDEL-type retention signal, indicated in...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: RNA reprogramming of a-mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes pptx
... Group I intron trans-splicing is initiated by the binding of an exogenous guanosine (exoG) into the ribozyme guanosine-binding site. Sub- sequently, base pairing between the internal guide sequence ... intradomain (A–bul- ge ⁄ P4 interaction, and L5b–P6 tetraloop receptor interaction) and interdomain (P14 pseudoknot base- pairing) tertiary interactions. DiGIR2 has a less complex structure wit...
Ngày tải lên: 23/03/2014, 11:20
Báo cáo khoa học: Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand pdf
... other kinetoplastid sequences annotated as Rpa1, lacked the N-terminal domain (data not shown) that in other eukaryotes is involved only in Rpa–protein interactions and has no function in binding ... m M )usedinnormal reactions and varying concentrations of KCl (0–800 m M ). UV cross-linking assays UV cross-linking in solution was p erformed on ice by exposing t he 20 lL binding react...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Crystal structures of bovine odorant-binding protein in complex with odorant molecules doc
... of OBP in signal triggering remains unresolved. 3 Keywords: crystal str ucture; domain swapping; odorant- binding protein; olfaction. Odorant-binding proteins (OBPs), first discovered in the nasal ... igh- affinity binding with empty porcine OBP, although binding was further localized in several t issues besides nasal mucosa. Another class of lipocalins – tear lipocalin-1 – was shown to...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo khoa học: "Immunolocalization of anion exchanger 1 (Band 3) in the renal collecting duct of the common marmoset" pptx
... intense in the CCD and OMCD, whereas immunolabeling of intracellular vesicles was more intense in the CNT. In addition, we found that there was no immunolabeing in the mitochondria of type A inter- acted ... in collecting duct of human kidney. Am J Physiol Renal Physiol 1987, 253, F213-221. 19. Weiner ID, Hamm LL. Regulation of intracellular pH in the rabbit cortical collecti...
Ngày tải lên: 07/08/2014, 20:23
Báo cáo khoa học: "Quantitative variations of taxifolin and its glucoside in Pinus sylvestris needles consumed by Diprion pini larvae" pptx
... during feeding tests and insect defoliation both induced a strong glucosilation of taxifolin in needles (table I). High rates of mortality of Diprion pini larvae were associated ... when the insects were fed with shoots without T or with shoots sprayed with T. However, this feeding bio- assay was preliminary and no experiments were made w...
Ngày tải lên: 08/08/2014, 19:21
Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"
... increase in urine Cu levels in patients suffering from myocar- dial infarction (MI) (15). Reunanen et al. (1996) found increased levels of serum Cu in patients with CAD (14). In contrast, in our ... patients with CAD compared to the control group. Other investigators have also re- ported decreased retinol levels in patients with CAD (31,32). In other studies,...
Ngày tải lên: 25/10/2012, 10:51
báo cáo hóa học: " Predictors of health-related quality of life in patients with colorectal cancer" doc
... HRQL that combined data from patients with colorectal cancer and patients with other diagnoses such as breast or lung cancer [12-14] may have failed to identify relationships involving dis- ease- ... physical function and well-being in colorectal cancer patients that is useful as a patient-reported outcome in pharmacologic interventions [21]. The TOI and the remaining two...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Adalimumab improves health-related quality of life in patients with moderate to severe plaque psoriasis compared with the United States general population norms: Results from a randomized, controlled Phase III study" pdf
... evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratio to adalimumab 80 mg (two 40 mg injections administered ... symp- tomatology, including pain and itching, combined with concerns about the appearance of one's skin can substan- tially affect a patient's psychological well...
Ngày tải lên: 18/06/2014, 19:20