Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx

... validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB. Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other ... inhibition of the caseinolytic activity in zymography by EDTA and lack of inhibition by the serine protease inhibitor phenylmethylsulfonyl fluoride further co...

Ngày tải lên: 09/08/2014, 01:22

... controls and 3 cases at the defining moment of the construction of the data package. The funda- mental cause was the lack of fulfilment of the inclu- sion criteria. The assembly of the previous data ... outliers; they were included in the final quality control because they could not be excluded based on the eligibility criteria. A normality study of the qu...

Ngày tải lên: 03/11/2012, 11:34

... whilst other components of the system (photo- system I an d the H + -ATPase) are located in the unstacked thylakoid membranes [1±3]. The location o f t he fourth component of the photosynthetic system, ... survey of previous structural studies of thylakoid membranes [13,16,17,21, 29±32] suggests that they may be newly interpreted in terms of the alternative model of...

Ngày tải lên: 17/03/2014, 17:20

... strengthened CO 2 gas conditions. On the other hand, the emergence of antibiotic resistant H. pylori strains has been increasing and the problems for the chemotherapy have also been growing. The ... followed by the Rice-fluid derived from usually cooked Japanese rice. The number of viable H. pylori cells decreased progressively by exposure to the Rice-fluid and rea...

Ngày tải lên: 31/10/2012, 17:03

... mucopolysaccharidosis type I because they imply that the introduction of a therapeutic IDUA gene by lentiviral vector into a small portion of target cells may result in the release of the expressed enzyme from these ... may be used for the delivery and expression of the IDUA gene to cells in vivo for treatment of MPS I. Keywords: MPS I; Hurler syndrome; a- L -iduronida...

Ngày tải lên: 24/03/2014, 04:21

... by a user in the gray- shaded triangular area of Figure 2; the other one for which the investigated cell (i.e., AP 13) has the smallest dynamics. Obviously, both dynamics differently impact the ... D.) LetuslastnoticethatthechoiceforvaluesofM and J is a trad e-off between different aspects: cardinality of the resulting typical set (i.e., tractable number of points), number...

Ngày tải lên: 21/06/2014, 00:20

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Ngày tải lên: 07/08/2014, 18:21

... regulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with fibroblast-like synoviocytes, and that IP-10 may contribute to the recruitment of specific ... may be expressed in the inflamed synovium of RA, and appears to play an important role in the recruitment of Th1-type cells into the joint. Thus, the aim of the pres...

Ngày tải lên: 09/08/2014, 01:21

... the development of quality indicators during the consensus procedure of phase 1 of the study and the applicability testing of phase 2 of the study. Hermanides et al. AIDS Research and Therapy ... was performed using PubMed to iden- tify already existing quality of care indicators for the care of H IV-infected pregnant women. On the basis of the available lite...

Ngày tải lên: 10/08/2014, 05:22

... until the time of the plasma PAF-AH assay analysis. From the pellet of the 1st centrifugation (leukocytes and erythrocytes) the isolation of the leukocytes from the contaminating erythrocytes ... homogenates of rabbit leukocytes. The in vitro enzymatic assay of Lyso-PAF-AT was performed in the presence of several concentrations of each drug in the assay r...

Ngày tải lên: 11/08/2014, 03:20