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Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx

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Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx

... validity of the new model for the analysis of the mechanisms of cartilagedestruction by SFB. Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other ... inhibition of the caseinolyticactivity in zymography by EDTA and lack of inhibition by the serine protease inhibitor phenylmethylsulfonyl fluoride furtherconfirmed the MMP character of the bands ... stimulated synovial fibroblasts suppressed the synthesis of collagen type IImRNA in cartilage.Conclusions The results demonstrate for the first time the capacity of synovial fibroblasts to degrade intact...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"

... controls and 3 cases at the defining moment of the construction of the data package. The funda-mental cause was the lack of fulfilment of the inclu-sion criteria. The assembly of the previous data ... outliers; they were included in the final quality control because they could not be excluded based on the eligibility criteria. A normality study of the quantitative variables in the combined ... both the controls and the cases, by means of the Kolmo-gorov-Smirnov test [19]. A bivariate analysis was made by means of the Mann-Whitney U- test [19]. A logistic regression (LR) analysis...
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Báo cáo Y học: An alternative model for photosystem II/light harvesting complex II in grana membranes based on cryo-electron microscopy studies pptx

Báo cáo Y học: An alternative model for photosystem II/light harvesting complex II in grana membranes based on cryo-electron microscopy studies pptx

... whilst other components of the system (photo-system I an d the H+-ATPase) are located in the unstackedthylakoid membranes [1±3]. The location o f t he fourthcomponent of the photosynthetic system, ... survey of previous structural studies of thylakoid membranes [13,16,17,21, 29±32] suggests thatthey may be newly interpreted in terms of the alternative model of thylakoid structure. A review of ... reasonably evenly sampled by the data. Neverthe-less, the physical restriction imposed by the specimen holderin the microscope means that there is a Ômissing coneÕ of datacorresponding to tilts beyond...
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Báo cáo y học: "In vitro bactericidal activities of Japanese rice-fluid against Helicobacter pylori strains"

... strengthened CO2 gas conditions. On the other hand, the emergence of antibiotic resistant H. pylori strains has been increasing and the problems for the chemotherapy have also been growing. The ... followed by the Rice-fluid derived from usually cooked Japanese rice. The number of viable H. pylori cells decreased progressively by exposure to the Rice-fluid and reached less than the assay limit ... strains of K. pneumoniae and two strains of K. oxytoca, respectively (data not shown). Effect on Morphology of H. pylori The results of morphological study are shown in Fig. 4. H. pylori cells...
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Báo cáo Y học: In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors pdf

Báo cáo Y học: In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors pdf

... mucopolysaccharidosis type I because theyimply that the introduction of a therapeutic IDUA geneby lentiviral vector into a small portion of target cellsmay result in the release of the expressed enzyme fromthese ... may be used for the delivery and expression of the IDUA gene to cellsin vivo for treatment of MPS I.Keywords: MPS I; Hurler syndrome; a-L-iduronidase; genetherapy.Mucopolysaccharidosis type ... direct enzyme replacement [19] and the murine knock-out model [20] represents a promising tool for the development of new therapies. The availability of the MPS I murine model and the recent...
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Báo cáo hóa học: " An analytical model for the intercell interference power in the downlink of wireless cellular networks" ppt

... by a user in the gray-shaded triangular area of Figure 2; the other one for which the investigated cell (i.e., AP 13) has the smallestdynamics. Obviously, both dynamics differently impact the ... D.)LetuslastnoticethatthechoiceforvaluesofM andJis a trad e-off between different aspects: cardinality of the resulting typical set (i.e., tractable number of points),number of simulation runs and accuracy of the ... method, we derive an analytical model for the pdf of the interce ll interference powerby slightly modifying a Burr probability distribution.This model is parameterized by the lognormal stan-dard...
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Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx

... regulated not only by inflammatorycytokines but also by the physical interaction of activatedleukocytes with fibroblast-like synoviocytes, and that IP-10 maycontribute to the recruitment of specific ... maybe expressed in the inflamed synovium of RA, and appearsto play an important role in the recruitment of Th1-typecells into the joint. Thus, the aim of the present study wasto examine the ... primaryantibody, and biotinylated polyclonal goat anti-IP-10(0.1 µg/ml) served as the secondary antibody. The sensi-tivity limit for the IP-10 enzyme-linked immunosorbentassay was approximately...
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Báo cáo y học: " Developing quality indicators for the care of HIVinfected pregnant women in the Dutch Caribbea" pot

... the development of quality indicators during the consensus procedure of phase 1 of the study and the applicability testing of phase 2 of the study.Hermanides et al. AIDS Research and Therapy ... was performed using PubMed to iden-tify already existing quality of care indicators for the care of H IV-infected pregnant women. On the basis of the available literature, the level of evidence ... hospitals for their contribution to the data collection: the gynaecology department,internal medicine department and the paediatric department of the StElisabeth Hospital of Curaçao, the gynaecology...
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Báo cáo y học: "In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin." potx

... until the time of the plasma PAF-AH assay analysis. From the pellet of the 1st centrifugation (leukocytesand erythrocytes) the isolation of the leukocytes from the contaminating erythrocytes ... homogenates of rabbit leukocytes. The in vitro enzymatic assay of Lyso-PAF-AT was performed in the presence of several concentrations of each drug in the assay reaction mixture as previously described ... until the time of the PAF-CPT and Lyso-PAF-AT assays analysis. DTT-insensitive PAF-Cholinephosphotransferase (PAF-CPT)activity assaysAssay was performed on the homogenates of rabb it leu-kocytes...
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