... validity ofthe new modelfortheanalysisofthe mechanisms of cartilage destruction by SFB Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible forthe cleavage of other extracellular ... established the modified, present form ofthe model, performed the real-time PCR, the immunohistochemistry and the respective data analyses and wrote the manuscript D Pohlers performed some ofthe experiments ... basis of their known caseinolytic activity and the molecular weight of their latent and active forms were then identified by western blot analysisofthe same pooled supernatants Western Blot for...
... providing thebaseforthe development of individual and more efficient anticancer treatment regimens However, most experimental data are based on either animal models, the extrapolation of which ... treatment for patients with NSCLC The complete analysisofthe part infiltrating cells might play within the tumor scenario, which would have exceed the extent of this study, is a necessary theme of ... responsible forthe surgical part ofthe investigation CM and ARR carried out the LIFE/DEAD-assay and 2-photon microscopy PZ was involved in the design ofthe study, evaluation ofthe results...
... structure of C24 Doc S1b sbml format ofmodel structure of C24 Doc S2a Model structure of Rsch Doc S2b sbml format ofmodel structure of Rsch Doc S3 Documentation ofthemodel structure This supplementary ... assessment ofthe trajectory of interconversion rates as a function of time of cold exposure, (b) comparison ofthe magnitudes ofthe various interconversion rates, and (c) lineup ofthe accessions ... also depends on the concentration ofthe reaction product and the dissociation constant Ki,B for inhibitor binding The rate of hexose-based sucrose synthesis was described by the mass action...
... suffer from the formation of new “cluster” species observed with the use of more reactive gases such as ammonia The performance of CRC based ICP-MS instruments cannot, however, match the detection ... interferences The Agilent 7500c, featuring the Octopole Reaction System (ORS) works well forthe removal of carbon-based interferences The ORS employs simple reaction gases (H2 and He), and therefore ... used, rather than pure oxygen, avoiding the use of highly flammable or explosive gases in the laboratory The oxygen is added either in the spray chamber or using a T-connector before the torch...
... information Whether or not the baseNP information can improve the precision of POS tagging in our approach is determined by the identifier assignment ofthe baseNP rules when training trigram model ... one ofthe N-best POS tagging result ofthe sentence is: T = NN VBD RB CD NNS NN NN For this POS sequence, the 2nd pass will try to determine the baseNPs as shown in Figure The details ofthe ... improve the precision of both baseNP and POS tagging This is one of our further research topics (2) Our statistical model makes use of more lexical information than other approaches Every word in the...
... wetted function is 1. For other cases, value ofthe cell side wetted function equals to the ratio ofthe length ofthe wetted portion over the total length ofthe cell side. After getting all the wetted points on four sides ofthe cell, ... five meshes from the lateral boundaries, and then increases linearly with the distances from the boundaries towards the ends ofthe wave absorbing zones. Finally, at the ends ofthe wave ... To verify the accuracy ofthe numerical model on the simulation ofthe wave transformation on a natural beach, existing experimental data on the wave dynamics in the nearshore ...
... reflectance in the visible yet reduced reflectance in the NIR and SWIR regions ofthe spectrum Analysis of vegetation spectra 519 Figure Summary of F-ratio tests of significance ofthe variance ofthe ... effects In the eucalypt data they arise due to plot (site) and tree effects The expected power spectrum for a given group is one for which the random effects are zero Estimation ofthemodel parameters ... differences in these factors are also conjectured forthe eucalypt foliage These a priori expectations were tested with the null hypothesis of no treatment viz no species effect With the assumption of a...
... Indeed the realistic modeling ofthe death of certain organs or whole branches is one ofthe difficulties raised by the models ofthe structurefunction type MAIN CHARACTERISTICS OF EMILION MODEL ... outputs ofthemodelThe maximum duration of a simulation is one year, because EMILION does not modelthe development ofthe Scene and the Structure Themodel does not include any description of organ ... sources forthe rest ofthe tree The contribution ofthe oldest branches to the tree can be neglected; they present lower positive carbon balance, permitting them to cover their own needs until their...
... Morphological analysis In the second case ofthe figure, the heterozygote deficit (f) must be considered The frequency ofthe phenotype A+ is the sum ofthe frequency ofthe genotype P : +/+ All ofthe ... means ofthe comparison ofthe RAPD marker frequencies of a subsampling of these progenies and ofthe adult population Analysisofthe morphological characters MATERIALS AND METHODS Sampling The ... classified in the space ofthe other species over the analyses Molecular analyses The allele frequencies ofthe RAPD loci in the adult trees ofthe stand, calculated according to the two hypotheses:...
... on the other hand, is homozygous forthe « high » allele (A All ofthe l ) l progeny from the standard cross have inherited the A allele from the father and are, therefore, heterozygous A The ... outline the sequence ofanalysis using a hypothetical example The hypothetical standard for this example is homozygous for « - » alleles (M ATHER & JINKS, 1982) and has low expression ofthe character ... of 2.0, and the l other allele (A had no effect on thebase phenotype of 10 The sampled population ) had allelic frequencies of A l A 0.5 A total of 25 isofemales were randomly sampled from the...
... 5.0 g of barium titanate were then distributed in the dust chamber prior to each shot, and a filter paper was inserted to block the dust chamber from the barrel ofthe rifle The other end ofthe ... were perforated by the projectile or fragments of them The photo-optic macroscopic analysisofthe gelatin blocks, however, already revealed significant differences in the character ofthe permanent ... differences in the diameter ofthe cavity between the two projectiles were found 6.0-10.0 cm behind the point Page ofof impact ofthe projectile on the gelatin block In this area, the gelatin blocks...
... weak acids, and the SID of standard starch preparations is zero (Table 6) Their acidbase effects are therefore likely to be similar to those of saline and the weak acid colloids [17] ‘Balanced’ ... Infusion of any of these fluids reduces plasma and extracellular SID by the same equilibration mechanism, irrespective of whether plasma [Cl–] rises or falls, forcing acidbase in the direction of ... tend to offset theacidbase effects of ATOT infusion As a result the overall tendency of standard albumin and gelatin based colloids to cause metabolic acidosis is probably similar to that of saline...
... is the various definitions used to describe the types ofacidbase disorder The development and implementation ofthe physical chemical approach has made identifying the etiology ofacidbase ... describe theacidbase state The absence of a uniform classification system and different study designs limit our ability to appreciate fully the incidence ofthe various acidbase categories For ... to the SIDa, which is one ofthe independent variables that comprise acidbase equilibria Therefore, if a metabolic acidosis is present and the SIG or lactate does not make up the majority of the...
... B of Figure Because ofthe non-uniformity ofthe variance (the differences between each pair of insulin sensitivity indices depend on the values ofthe computed indices), the logarithms ofthe ... concentrations as the true forcing function for glucose kinetics Figures and show the performance ofthe two models in terms of their ability to describe the observed data The apparent better fit ofthe Minimal ... estimate an index of IR is, of course, crucial for any model aiming at being useful to diabetologists Part ofthe problem ofthe lack of identifiability ofthe SI from the MM may reside in the MM being...
... (4) The null hypothesis states that there is no QTL affecting the clonal expansion ofthe cells (the reduced model) , whereas the alternative states that such a QTL does exist (the full model) The ... the marker-QTL genotype frequencies are identical forthe two groups, the effects ofthe QTL may be different because ofthe impact of environPage of (page number not for citation purposes) Theoretical ... http://www.tbiomed.com/content/5/1/7 The LR is asymptotically χ 2-distributed with one degree of freedom A similar test forthe existence of a QTL can be performed on the basis ofthe hypotheses about genotypic-specific...
... width of portion ofthe peak above the significance cutoff, 'array density' ofthe peak, and the P value for that peak The array density value is defined as the average number of arrayed elements ... in the ROC curves by the low true-positive rate at the extreme left ofthe plot (b) The 95% confidence interval forthe AUC for each analysis technique was estimated by bootstrap resampling of ... defined as the distance between the start of one arrayed element and the start ofthe next Thereby, the measurement recorded at each arrayed element will be used in the calculation of at least...
... (99%) ofthe data from a negative control The gradual nature of these types of responses supports the use of regression analysis Because the effect may deviate from linearity in the range of perturbations ... with the technical aspects of data import and management, and refer the interested reader to the documentation ofthe software package prada for a thorough discussion of these [19] Selection of ... used forthe different assays, each specifically measuring the phenotype of interest In the case of cell proliferation, the antibody detected the incorporation ofthe thymidine analog BrdU into the...
... Profiles fortheAnalysisof Diseases LIM JUNLIANG KEVIN (B.Comp (Hons.), NUS) A DOCTORAL THESIS SUBMITTED FORTHE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF COMPUTER SCIENCE NATIONAL UNIVERSITY OF ... set of genes ofthe same size as the pathway being evaluated The p-value assigned for a pathway is the proportion of permutations that have aggregated scores higher than the score computed forthe ... depends on the correlation ofthe gene with the one ofthe two phenotypes We theref phenotype The enrichment score is the maximum deviation from Moreover, in the permutation test the FCS and...
... β-CD-NH2 and the backward movement ofthe neutral sample partitioned in the micelles of sodium dodecyl sulfate (SDS) Stability ofthe inclusion complexes formed between the carrier and the solute ... displacer plug was introduced before sample injection to reduce the length ofthe concentrated sample zone and increase the peak height by slowing down the forward movement ofthe neutral sample associated ... With the high separation efficiency, high resolution and portability, CE has been proven a powerful method forthe studies of many groups of compounds The improvement of sensitivity and the miniaturization...