Báo cáo y học: "The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus" potx
Báo cáo y học: "The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus" potx
... V H gene < /b> repertoire < /b> of < /b> splenic < /b> B cells and somatic hypermutation in systemic lupus erythematosus Nicola L W Fraser 1 , Gary Rowley 1 , Max Field 2 and David I Stott 1 1 Division of < /b> Immunology, Infection ... 1, and has two distinct areas of < /b> staining for FDC and one large area of < /b> B cells encompassing both FDC regions. V...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study" docx
... between inflammatory mark- ers and pain threshold [52]. These inconsistencies may be due to differences in the sites of < /b> testing (i.e. joints vs. non-joint sites) and/ or confounding by other variables, ... has been demonstrated in animals, healthy individuals and individuals with RA [45], but the role of < /b> central pain processing in RA has been largely understudied. Stu...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo Y học: The reductive hotspot hypothesis of mammalian aging Membrane metabolism magnifies mutant mitochondrial mischief pptx
... The involve- ment of < /b> cytochrome b 5 reductase (but not, interestingly, of < /b> cytochrome b 5 ) [47] opens the possibility of < /b> one-electron redox processes being involved, which make it more likely that ... mitochondrion-driven aging are inadequate has already stimulated much relevant work, which has been brie y < /b> surveyed here and in the accompanying minireviews b...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
... Ohno-Iwashita, Y.< /b> (1995) Interaction of < /b> theta-toxin (perfringolysin O), a cholesterol- binding cytolysin, with liposomal membranes: change in the aro- matic side chains upon binding and insertion. Biochemistry ... cholesterol- dependent binding. We have previously shown that BCh binds selectively to lipid rafts in intact platelets [7]. To analyze the selectivity of < /b>...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The cold-active lipase of Pseudomonas fragi Heterologous expression, biochemical characterization and molecular modeling pdf
... coordinated to the metal ion by one carboxylic oxygen atom belonging to the side chain. The Ca ion is coordinated also by the backbone carbonyl groups of < /b> H266 and R269. Bond distances and angles involving ... involved in hydrogen bonds with the side-chains of < /b> S211 and D212 (S244 and T245 in BCL). In PFL, these residues are substituted by L219 and H220. Due to the...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking pdf
... persistent hyperinsulinaemic hypoglycaemia of < /b> infancy [12] cluster in this domain of < /b> the protein. Persistent hyperinsulinaemic hypoglycaemia of < /b> infancy is an hereditary disease char- acterized by inappropriately high ... the binding resin was pelleted by centrifugation (20 000 g for 2 min at 4 °C) followed by five washes with 1 mL binding buffer. Bound protein was recove...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: The C-terminal region of ammodytoxins is important but not sufficient for neurotoxicity pot
... presynaptic membrane [6], after which they are presumably endocytosed. In the nerve cell, they may inhibit the recycling of < /b> synaptic vesicles by binding to certain target proteins [7] and hydrolyzing ... Atxs in about 30% of < /b> residues, but were able to interact with both Atx-binding proteins. The ability of < /b> the chimeric proteins to inhibit 125 I-labeled AtxC binding...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect" pptx
... years of < /b> age in the United States. Efficacy and safety Levocetirizine is a potent antihistamine as demonstrated by its ability to inhibit cutaneous histamine-induced itch- ing and the wheal and ... recently levocetirizine and desloratadine were compared for their ability to inhibit allergen- induced wheal and flare in a double-blind, randomized, cross-over, placebo-contr...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "The psychological well-being of children orphaned by AIDS in Cape Town, South Africa" pptx
... children orphaned by AIDS may have unmet psychological needs. The finding of < /b> strikingly high PTSD-type symptoms in this study indicate that this should be a key area for research and intervention. ... Journal of < /b> Child Psychology and Psychiatry and Allied Dis- ciplines 1997, 38(5):581-586. 40. Dyregrov A, Yule W: Screening measures - the development of < /b> the UNICEF s...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions" potx
... swings resembling a cyclothymic or dys- thymic disorder, but they also tend to diminish and disap- pear with time. The presence of < /b> the dysthymic symptoms usually indicates the normal course of < /b> ... possibly in all age groups because of < /b> possible induction of < /b> suicidality (thinking and behaviour but not completed suicide) by antidepressants in juvenile depressi...
Ngày tải lên: 08/08/2014, 23:21