the nervous system in systemic lupus erythematosus
Báo cáo y học: "The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus" potx
... from a patient with systemic lupus erythematosus (a) Anti-FDC (follicular dendritic cell) staining within the area known as germinal centre (GC) A (b) Staining for CD20 FDC staining suggests two ... mutations within the CDRs, of which the most prevalent was from serine to asparagine; other mutations included serine to threonine, tyrosine, aspartate, methionine and proline Discussion The immunohistology ... cells The aims of the present study were to identify the immunoglobulin V genes used by proliferating B cell clones in GCs of a SLE spleen, and to determine whether there are abnormalities in the...
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Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx
... Takeda T, Inoue T: Serum levels of interferons in patients with systemic lupus erythematosus Clin Exp Immunol 1987, 70:562-569 Hooks JJ, Moutsopoulos HM, Notkins AL: Circulating interferon in human ... N, Winchester RJ: The 1982 revised criteria for the classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Gladman DD, Ibanez D, Urowitz MB: Systemic lupus erythematosus ... background of systemic lupus erythematosus: insights from Asia Autoimmunity 2005, 38:347-352 Means TK, Luster AD: Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus...
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Báo cáo y học: "Practical and theoretical barriers to the prevention of accelerated atherosclerosis in systemic lupus erythematosus" docx
... cardiovascular risk factors in systemic lupus erythematosus J Musculoskel Med 1998, 15: 42-52 El-Magadmi M, Ahmad Y, Wajed J, Bruce IN: The bimodal mortality pattern in systemic lupus erythematosus Curr ... factors of carotid plaque in women with systemic lupus erythematosus Arthritis Rheum 1999, 42:51-60 Salmon JE, Roman MJ: Accelerated atherosclerosis in systemic lupus erythematosus: implications ... Kong TQ, Kellum RE, Haserick JR: Clinical diagnosis of cardiac involvement in systemic lupus erythematosus: a correlation of clinical and autopsy findings in thirty patients Circulation 1962,...
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Báo cáo y học: "Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations" ppt
... iodide staining, according to the method of Nicoletti and colleagues [19], and by the binding of FITCconjugated Annexin V, using the Apoptest binding kit, containing annexin V-FITC and binding buffer ... manifestations other than anxiety Differences between the groups as measured by the χ2 test were not statistically significant SLE, systemic lupus erythematosus; SLEDAI, Systemic Lupus Erythematosus ... 10 at 4°C and then soaked in balanced salt solution (Sigma) for 30 at 25°C Cells were then incubated for 30 at 25°C in the blocking buffer (2% bovine serum albumin in PBS, containing 5% glycerol...
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Báo cáo y học: "Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases" pps
... proteins and DNA by high NaCl and possibly secondary conformational changes help the binding of anti-RPA antibodies in autoimmune sera We examined whether the binding of DNA to RPA can interfere the ... ELISA with the recombinant RPA32 protein Antibodies against RPA32 were found in 10.9% (87 of 801) in breast cancer patients and in 10.3% (4 of 39) in intraductal in situ carcinoma patients, in contrast ... autoantibodies by incubating affinity-purified RPA with ssDNA, dsDNA, or dsRNA before antibody binding When the RPA was incubated with ssDNA or dsDNA before the reaction with autoimmune sera, the binding of...
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Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf
... blockade in patients with systemic lupus erythematosus While dampening inflammation, TNF blockade with infliximab induced an increase of autoantibodies in five out of seven patients and increases in ... on infliximab therapy in SLE suggests that, in combination with azathioprine, infliximab may turn out to be an interesting therapeutic option in selected patients with SLE and in particular in ... activity in systemic lupus erythematosus Clin Rheumatol 1999, 18:17-22 44 Aringer M, Stummvoll GH, Steiner G, Koller M, Steiner CW, Hofler E, Hiesberger H, Smolen JS, Graninger WB: Serum interleukin-15...
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Báo cáo y học: "Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region" pot
... significant; SLE, systemic lupus erythematosus; STAT, signal transducers and activators of transcription Table Logistic regression analysis of the systemic lupus erythematosus- associated single nucleotide ... of systemic lupus erythematosus Arthritis Rheum 1997, 40:1725 23 Schildkraut JM: Examining complex genetic interactions In Approach to Gene Mapping in Complex Human Diseases Edited by: Haines ... Kristjansdottir H, Steinsson K, Alm G, Rönnblom L, Syvänen AC: Polymorphisms in the tyrosine kinase and interferon regulatory factor genes are associated with systemic lupus erythematosus Am J Hum...
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Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx
... Takeda T, Inoue T: Serum levels of interferons in patients with systemic lupus erythematosus Clin Exp Immunol 1987, 70:562-569 Hooks JJ, Moutsopoulos HM, Notkins AL: Circulating interferon in human ... N, Winchester RJ: The 1982 revised criteria for the classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Gladman DD, Ibanez D, Urowitz MB: Systemic lupus erythematosus ... background of systemic lupus erythematosus: insights from Asia Autoimmunity 2005, 38:347-352 Means TK, Luster AD: Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus...
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báo cáo khoa học: "Pigmented villonodular synovitis of the hip in systemic lupus erythematosus: a case report" pptx
... responding to immunosuppressive therapy in lupus patients should raise suspicion of alternative diagnoses such as PVNS Page of Competing interests The authors declare that they have no competing interests ... the synovial fluid effusion (white) in the dorsal recessus of the joint around the femoral head (B) Gadolinium contrast of sagittal images shows diffuse enhancement in synovial tissue along the ... markers in proliferating synovial cells Histopathology 2005, 46:490-497 doi:10.1186/1752-1947-5-443 Cite this article as: Anders: Pigmented villonodular synovitis of the hip in systemic lupus erythematosus: ...
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Báo cáo y học: " The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus" doc
... C-reactive protein in systemic lupus erythematosus Lupus 2009, 18:966-973 44 McMahon M, Hahn BH: Atherosclerosis and systemic lupus erythematosus - mechanistic basis of the association Curr Opin Immunol ... assessment and treatment in systemic lupus erythematosus Best Practice Res Clin Rheumatol 2009, 23:481-494 83 Meyer O: Anti-CRP antibodies in systemic lupus erythematosus Joint Bone Spine 2010, 77:384-389 ... population dynamics in systemic lupus erythematosus Arthritis Rheum 2009, 60:1472-1483 52 Chung CP, Long AG, Solus JF, Rho YH, Oeser A, Raggi P, Stein CM: Adipocytokines in systemic lupus erythematosus: ...
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Báo cáo y học: "Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis" pot
... process in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) even though both Gas6 and sAxl in most of the patients were within the normal range [13] Systemic lupus erythematosus ... participated in the analysis of experimental data and in the writing of the manuscript AJ, GS, AAB, AG, BL, EL and TS participated in the design of the study, in the analysis of the patient cohorts, in the ... activity in systemic lupus erythematosus Rheumatology (Oxford) 2011, 50:1064-9 14 Katsiari CG, Liossis SN, Sfikakis PP: The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: ...
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Báo cáo y học: "Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies" pdf
... Mexican Systemic Lupus Erythematosus Disease Activity Index and the Systemic Lupus International Collaborating Clinics/American Collage of Rheumatology Damage Indexes at the beginning of the study ... cytomegalovirus; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index; SLICC, Systemic Lupus International Collaborating Clinics aInformation for treatment was available in 19 patients in this group ... Snaith M, Sturfelt G: The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic lupus erythematosus Arthritis...
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Báo cáo y học: "Cytokines in systemic lupus erythematosus, London, UK" ppt
... PM, Isenberg DA: The effect of interleukin-10 and interleukin-12 on the in- vitro production of antidouble-stranded DNA antibodies from patients with systemic lupus erythematosus Clin Exp Immunol ... factor-α: the Janus cytokine In NZB/W F1 mice, the administration of TNF-α reduces the severity of the lupus- like illness [6] This observation has not been repeated in other lupus- prone mouse strains ... meeting showed the breadth of interest in the role played by different cytokines in SLE A large amount of work in mice, and a smaller body of evidence on the effects of anticytokine antibodies in...
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Báo cáo y học: "Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus" potx
... cytokine interleukin-6 Biochem Pharmacol 2000, 60:1185-1195 33 Cross JT, Benton HP: The roles of interleukin-6 and interleukin-10 in B cell hyperactivity in systemic lupus erythematosus Inflamm ... DC-poietins in systemic lupus erythematosus Hum Immunol 2002, 63:1172-1180 47 Scheinecker C, Zwolfer B, Koller M, Manner G, Smolen JS: Alterations of dendritic cells in systemic lupus erythematosus: ... JS: Interferon-gamma induced exacerbation of systemic lupus erythematosus J Rheumatol 1990, 17: 831-832 39 Graninger WB, Hassfeld W, Pesau BB, Machold KP, Zielinski CC, Smolen JS: Induction of systemic...
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Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx
... Symmons D, Zoma A: The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus Arthritis ... protein autoantibody; CRP, C-reactive protein; mSLEDAI, modified systemic lupus erythematosus disease activity index; n.s., not significant; SLEDAI, systemic lupus erythematosus disease activity index ... environmental, and infectious risk factors for developing systemic lupus erythematosus Arthritis Rheum 1998, 41:1714-1724 Robson MG, Walport MJ: Pathogenesis of systemic lupus erythematosus Clin Exp Allergy...
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Báo cáo y học: "Autoantibody profile in systemic lupus erythematosus with psychiatric manifestations: a role for anti-endothelial-cell antibodies" docx
... impairment in systemic lupus erythematosus Arthritis Rheum 1992, 35:411-416 Lindal E, Thorlacius S, Steinsson K, Stefansson JG: Psychiatric disorders among subjects with systemic lupus erythematosus in ... manifestations of systemic lupus erythematosus Aust N Z J Med 1988, 18:679-684 Johnson RT, Richardson EP: The neurological manifestations of systemic lupus erythematosus Medicine 1968, 47:337-369 Wekking EM: ... Psychiatric symptoms in systemic lupus erythematosus: an update Psychosom Med 1993, 55:219-228 24 25 26 27 R371 Iverson GL, McCracken LM: Attributing psychopathology to systemic lupus erythematosus: some...
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Báo cáo y học: "B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels" ppsx
... final version of the manuscript DMH assisted in the design in the study, in the interpretation of the results, and in writing the final version of the manuscript DN assisted in the design in the ... of the results and in writing the final version of the manuscript TSM performed the plasma BLyS protein and anti-BLyS assays and assisted in the interpretation of the results and in writing the ... 20:829-833 Ginsburg WW, Finkelman FD, Lipsky PE: Circulating and pokeweed mitogen-induced immunoglobulin-secreting cells in systemic lupus erythematosus Clin Exp Immunol 1979, 35:76-88 Klinman DM,...
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Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
... K, Nived O, et al.: The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic lupus erythematosus Arthritis ... transforming growth factor-beta Lupus 1999, 8:95-102 Bruce IN, Gladman DD, Urowitz MB: Premature atherosclerosis in systemic lupus erythematosus Rheum Dis Clin North Am 2000, 26:257-278 Grainger ... SLE, systemic lupus erythematosus; TGF, transforming growth factor A relative Activation Index (AI) was calculated, by division of TGF-β1 levels in blood (A450) incubated at 37°C for 90 minutes...
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Báo cáo y học: "Targeting B cells in systemic lupus erythematosus: not just déjà vu all over again" pdf
... rates in B cell lymphomas than the agent alone [10] Such approaches also create more clinical adverse reactions and would probably not be acceptable for use in SLE Another curious finding in the ... might be the future for epratuzumab in SLE or perhaps other autoimmune diseases? In part, the rituximab experience will determine the way, because development of that drug is much further advanced, ... hour without serious infusion reactions, and so far no major toxicities have emerged One trivial possibility is that the binding of CD22 changes little in the organism, and thus the current randomized...
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Báo cáo y học: "Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus" ppsx
... inflammatory lesions in the vicinity of sunburn cells (SBCs) in patients with systemic lupus erythematosus (SLE) Haepatients with systemic lupus erythematosus (SLE) matoxylin eosin (H&E)-stained ... photosensitivity in systemic lupus erythematosus Ann Rheum Dis 1989, 48:461-463 Bijl M, Limburg PC, Kallenberg CG: New insights into the pathogenesis of systemic lupus erythematosus (SLE): the role of ... apoptotic keratinocytes by macrophages in the epidermis of patients with infiltrates (b) Representative biopsy showing CD68 staining combined with haematoxylin staining using diaminobenzidine (DAB)...
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