... overexpressing the EVH1 domain. These results indicate that the EVH1 intrabodies inhibit only the EVH1 domain function that regu- lates IL-2 synthesis signaling without affecting the overall domain structure of ... bind to the target proteins on the lumen side and inhibit transport of tar- get proteins in the process of functional maturation [6,8]. If...
Ngày tải lên: 16/03/2014, 14:20
... constants related to the binding of l-Arg [10–14] and NOHA [10], nothing is known about the thermodynamics and kinetics of the binding of guanidines and N-hydroxy- guanidines to iNOS. Removal of the a-amino ... that the binding of BuNOHG to iNOS is favoured slightly over its binding to nNOS. The K m value for the oxidation of BuNOHG by iNO...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Relationships between the ethanol utilization (alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans pptx
... Biochem. 27 0) Ó FEBS 2003 Relationships between the ethanol utilization ( alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans Michel Flipphi, Janina Kocialkowska and Be ´ atrice ... with either ethylamine or L -threonine as the nitrogen source (results not shown). Catabolism of L -proline and L -arginine does not lead to induction of...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx
... original French government works Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates Brice Korkmaz 1,2 , Gwenhael Je ´ got 1,2 , Laurie C. Lau 3 , Michael ... All other chemical reagents were of analytical grade. Design and synthesis of quenched fluorescent substrates Quenched fluorogenic substrates were e...
Ngày tải lên: 28/03/2014, 22:20
Báo cáo khóa học: Interaction between the 2¢)5¢ oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1 potx
... MBD1.F; lane 2, 2 lL of crude p59DUbL-V5 OASL; lane 3, 2 lL of crude p59. F-V5 OASL. Fig. 6. In vivo interaction between p59 OASL protein and MBD1. In vivo pull-down of MBD1 transfected into p59. F-V5 ... p59 OASL using a p59 OASL specific antibody (Fig. 3). Only the MBD1 fusion protein was able to pull down p59 OASL, while the GST control was negative. The...
Ngày tải lên: 30/03/2014, 13:20
Báo cáo khoa học: "Reading Between the Lines: Learning to Map High-level Instructions to Commands" ppt
... instruction into a sequence of commands, and then translates them into the cor- responding low-level instructions. hurting the model’s ability to leverage the look- ahead features. Finally, to demonstrate ... demonstrate the quality of the learned word–command alignments, we evaluate our method’s ability to paraphrase from high-level instructions to low-level instruct...
Ngày tải lên: 30/03/2014, 21:20
Báo cáo khoa học: Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase doc
... a mixture of < /b> proteins B and B .The < /b> relative abundance of < /b> p roteins B and B was assessed b y using SDS/PAGE and electrospray ionization (ESI)-MS. Incubation of < /b> the < /b> purified protein < /b> B /B mix at ... the < /b> hydrophobic ÔnorthernÕ half of < /b> the < /b> c ore of < /b> protein < /b> B interacted w ith the < /b> hydroxylase. Docki...
Ngày tải lên: 31/03/2014, 09:20
Báo cáo khoa học: " Associations between the clinical signs of chronic endometritis with ovarian cysts and body condition loss in German Holstein Friesian cows" docx
... means of the variables remaining in the logistic model for the incidence of ovarian cysts in Holstein Friesian cattle diagnosed with chronic clinical endometritis (CCE) Variable Stratum n Incidence ... found associations between the clinical signs of chronic endometritis and the incidence of ovarian cysts. In addition, a positive effect...
Ngày tải lên: 07/08/2014, 23:22
Báo cáo khoa học: "Comparison between the structure and function of chloroplasts at different levels of willow canopy during a growing season" ppsx
... an average, 6 typi- cal chloroplasts were analyzed from each sample of the 3 replicate plots. Results and Discussion At all studied levels of the canopy, the ratio of the ... Comparison between the structure and function of chloroplasts at different levels of willow canopy during a growing season E. Vapaavuori 1 A. Nurmi...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo khoa hoc:" Comparison between the three porcine RN genotypes for growth, carcass composition and meat quality traits" pptx
... of the à RN /RN à rn + /rn + =0 and à RN /rn + à rn + /rn + = 0 hypothesis) and of the dominance eect (test of the d = 0 hypothesis, with d = à RN /rn + 0.5(à RN /RN + µ rn + /rn + )) are shown. 3.2.1. ... bias, and results are presented relative to the control rn + /rn + genotype (à RN /RN à rn + /rn + and à RN /rn + à...
Ngày tải lên: 09/08/2014, 18:21
Báo cáo khoa hoc:" Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element" pps
... IRE- like RNA element into the ORF. Thus the HCV IRES dIV structure is properly positioned in the HCV mRNA to function as an IRE-like RNA element. Results RNA binding to hIRP1 Since the HCV IRES dIV structure ... the shape of the wild type HCV IRES dIV RNA structure. Conclusion: The HCV IRES dIV RNA structure is not an authentic IRE. The pos...
Ngày tải lên: 11/08/2014, 07:21
báo cáo khoa học: " EXACKTE2: Exploiting the clinical consultation as a knowledge transfer and exchange environment: a study protocol" docx
... Health Care. JG is a Tier 1 Canada Research Chair in Health Knowledge Transfer and Uptake and leads Knowledge Translation Canada (KT Canada), a national research network in Canada. FL, ML and ... Ottawa, Ottawa, Canada, 9 Department of General Practice, School of Public Health and Primary Care (Caphri), Maastricht University, Maastricht, The Netherlands and 10 Depa...
Ngày tải lên: 11/08/2014, 16:20
báo cáo khoa học:" Study on the clinical application of pulsed DC magnetic technology for tracking of intraoperative head motion during frameless stereotaxy" pdf
... pin fixation of the head is no longer required. For all other procedures, continuous tracking of head motion ensures automatic correction of spatial distortion with mechani- cal alteration of the head ... Central Page 1 of 16 (page number not for citation purposes) Head & Face Medicine Open Access Research Study on the clinical application of pul...
Ngày tải lên: 11/08/2014, 23:22
Báo cáo y học: "Associations between the HLA-A polymorphism and the clinical manifestations of Behcet’s disease" pps
... Associations between the HLA-A polymorphism and the clinical manifestations of Behcet’s disease. Arthritis Research & Therapy 2011 13:R49. Submit your next manuscript to BioMed Central and take ... collected the clinical data, performed statistical analysis, and drafted the manuscript. JYK genotyped the HLA gene. FT helped design the study. JWK helped col...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo khoa học: "Associations between the time of conception and the shape of the lactation curve in early lactation in Norwegian dairy cattle" pptx
... 53:5 http://www.actavetscand.com/content/53/1/5 Page 5 of 8 RESEARCH Open Access Associations between the time of conception and the shape of the lactation curve in early lactation in Norwegian dairy cattle Fredrik Andersen 1* , Olav ... to conception time in either way. However, the principal aim of this study was to investigate whether there...
Ngày tải lên: 12/08/2014, 18:22