Báo cáo khoa học: "The expression and cellular localization of phospholipase Disozymes in the developing mouse testis" pps

Ngày tải lên: 07/08/2014, 20:23

... hypothetical. Although most cystatins inhi- biting cathepsin L also inhibit cathepsin S, an inhibitory activity of cystatin F against cathepsin S has not yet been reported. The expression of the ... detailed study of the subcellular localization and transport of cystatin F in model U937 cells would be valuable in understanding the role of cystatin F in haematopoi...

Ngày tải lên: 21/02/2014, 01:21

... capable of phagocytosing myelin and damaging axons. In this study, we characterize the regional, temporal and cellular expression of CCR1, CCR2 and CCR5 mRNA in the spinal cord of rats with myelin ... apoptosis of infiltrating cells in the CNS of animals with EAE [80]. The limitation of inflammation seen in the CNS could also be the result of a dimi...

Ngày tải lên: 19/06/2014, 22:20

... ACMSD of the region surrounding the metal active site and the Arg47 likely involved in substrate binding. Discussion In this study, the expression of the human ACMSD transcript coding for the active ... relevant pathway. Indeed, most of the intracellular NAD in liver is synthesized from the amino acid rather than from dietary niacin and the formed dinucleot...

Ngày tải lên: 19/02/2014, 02:20

... substitution of glycine residues by alanine or proline and the exchange of proline by glycine. Glycine residues are frequently found at the C-terminal ends of a helices providing the conforma- tional ... functions in many plants beyond the scope of pigmentation and ultraviolet screening, e.g. in reproduction [1], in the defense against microbial pathogens and ins...

Ngày tải lên: 21/02/2014, 03:20

... dissociation of these two proteins inhibits the antiapoptotic activity of Bcl-2 by initiating the release of cytochrome c from mitochon- dria into the cytosol and increasing the activities of caspase 3 and ... with hVps34, and another that inhibits autophagy and involves an interaction with Bcl-2 and Bcl-xL. Accord- ingly, overexpression of Bcl-2 and Bcl-xL disru...

Ngày tải lên: 28/03/2014, 23:20

... strengthens the involvement of a caspase-like activity, in animal tissue of A. viridis, avoiding interference by generic proteas- es. In the two animal cell layers, the effect of the two inhibitors ... [7,52,57]. Nevertheless, independently of the resulting effect of the thermal stress, all mechanisms point to the involve- ment of oxidative stress in the earl...

Ngày tải lên: 30/03/2014, 10:20

... kDa polypeptide resulted instead in the expression of only t wo protein bands of 77 and 63 kDa [26]. M oreover, the initial characterization of iPLA 2 c in nonrecombinant cells demonstrated that ... position. Measurement of mRNA content and kinetics of mRNA species encoding individual iPLA 2 c isoforms Alterations in the amount of iPLA 2 c isoform expression co...

Ngày tải lên: 19/02/2014, 16:20

... a donor of propylamine groups in the metabolism of spermidine and spermine [2] and an intermediary in the trans-sulfuration pathway to cysteine, one of the three amino acids involved in glutathi- one ... to determine the functional role of the amino acid residues involved in each. The present report describes the cloning and subsequent functional refolding,...

Ngày tải lên: 08/03/2014, 08:20

... result of the lost Ca 2+ ⁄ CaM-binding site of the IQ domain, but the missing PH1- and coiled-coil domains may also change the subcellular localization of this version of Ras- GRF1. These domains ... (F340) increases, whereas the fluorescence intensity at 380 nm (F380) decreases upon the binding of Ca 2+ . The change in the ratio of F340 ⁄ F380 determined the...

Ngày tải lên: 19/02/2014, 18:20