Báo cáo khoa học: "Phenotype of peroxisome proliferator-activated receptor-α(PPARα)deficient mice on mixed background fed high fat diet" doc

... 239–244 Phenotype of peroxisome proliferator-activated receptor- α (PPAR α ) deficient mice on mixed background fed high fat diet Bang Hyun Kim, Young Suk Won 1 , Eun-Young Kim 2 , Mijung Yoon 2 , Ki-Taek ... Westphal, H. Gonzalez, F. J. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishme...

Ngày tải lên: 07/08/2014, 17:22

... Transactivation of PPAR by green tea 327 of PPAR α . A characteristic activation of PPAR α of Wy- 14,643 at 20-40 µ M and clofibrate at 100 µ M was noted. After several runs of the experiment, the concentration ... enzymes [9], trapping of ultimate carcinogens [16,18], inhibitory effect in respect of the nitrosation reaction [8], inhibition of cell proliferation-related activ...

Ngày tải lên: 07/08/2014, 18:20

... contains a strong rRNA pro- moter region. Conclusions Our studies, on the modulation of oat ADC gene expression in T. cruzi epimastigotes, have shown an early period of transient expression during ... the restriction enzyme, BstBI, only produced partial digestion of the DNA samples. On the other hand, the absence of a second hybridiza- tion band in lane 1 might be the result of...

Ngày tải lên: 19/02/2014, 07:20

... (1–4 l M of actin, containing 10–15% of pyrenyl-actin) there was no self- assembly of G-actin. We also observed proportionality of the initial rate of polymerization to nucleus concentration. In ... thermal denaturation. Actin is the major component of the thin filaments of muscle cells and of the cytoskeleton system of nonmuscle cells. It is therefore a very abundant protein...

Ngày tải lên: 20/02/2014, 23:20

... genomic context: exon- ic miRNA in noncoding transcripts, intronic miRNAs in noncoding transcripts, and intronic miRNAs in protein-coding transcripts [8,9]. Based on the accumulating knowledge on miRNA biogenesis, ... intron composed of the 5¢ donor site from the first intron of the human b-globin gene and the branch and 3¢ accep- tor site from the intron of an immunoglobulin gene he...

Ngày tải lên: 07/03/2014, 11:20

... the role of vasopressin receptors, we examined the effects of vasopressin agonists and antagonists on the hormone-induced translo- cation of P-LAP in NRK52E cells (Table 1). The level of P-LAP ... Dose- response experiments indicate that the effect of AVP is first detectable at a concentration of 10 n M (Fig. 3B), suggesting that the hormone can mediate its effect at physiologica...

Ngày tải lên: 08/03/2014, 02:20

... cell association of uPA-generating activity enhances the rate of formation of active uPA [34]. An alternative explanation for the effect of the xyloside on uPA and MMP-9 secretion could be that ... xyloside treatment of both control and PMA-stimulated J774 cells completely blocks the assembly of intact heparan sulfate and chondroitin sulfate proteoglycans that are destined for s...

Ngày tải lên: 08/03/2014, 08:20

... a con- centration of ATP or mevalonate of 0.05 mm, but no complete inhibition at the higher concentrations tested. This decrease in binding of MVK to LHR mRNA sug- gests that the ATP ⁄ mevalonate ... (LHR) present on cell membranes of gonadal tissues belongs to the family of leucine-rich repeat-containing G-protein-cou- pled receptors (LGRs) [1,2]. Interaction of luteinizing hor...

Ngày tải lên: 16/03/2014, 06:20

... concentration (not shown). In this system, carbaryl acted as an antagonist because simultaneous addition of 1 lm of a typical AhR ligand, b-naphthoflavone (BNF), and increasing concentrations of ... a number of dose–response assays with increasing concentrations of BNF were per- formed in the presence of different concentrations of carbaryl. As shown in Fig. 3A,B, the presence o...

Ngày tải lên: 16/03/2014, 10:20

... Proceedings of the ACL-IJCNLP 2009 Conference Short Papers, pages 249–252, Suntec, Singapore, 4 August 2009. c 2009 ACL and AFNLP Introduction of a new paraphrase generation tool based on Monte-Carlo ... generation systems. This paper first presents an alternative to decod- ing that is based on transformation rule application in section 2. In section 3 we propose a paraphrase generati...

Ngày tải lên: 17/03/2014, 02:20