... indicate that TM12 plays a key role in the progression of the ATP hydrolytic cycle in ABCB1 and, in particular, in coordinating conformational changes between the NBDs and transmembrane domains. Abbreviations ABC, ... label- ling according to the following relationship: t 1=2 ¼ Ln2 = k Statistical analysis All data manipulations and statistical analyses were per- formed using graphp...
Ngày tải lên: 06/03/2014, 22:21
... found in the FAD-binding domain (Fig. 2). From the alignment, it is clear that GALDH in plants lacks the histidine residue involved in covalent flavinylation in GUO, ALO and GLO, but contains a leucine ... or aggregation. Covalent flavinylation has also been associated with improving flavoprotein stability, a covalent flavin–pro- tein link is presumed to have a similar stabilizing e...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Light regulation of CaS, a novel phosphoprotein in the thylakoid membrane of Arabidopsis thaliana doc
... USA) and the uracil-containing primers nt114 (forward: GGCTTAAUATGGCTATGGCGGAAATGG CAACGA) and nt115 (reverse: GGTTTAAU TAAGGATC CTTAATTAAGCCTCAGCGGGTCGGAGCTAGGAAG GAACTT), where the underlined ... 5¢-AAATGGCAACGAAGTCTTCAC-3¢ and 5¢-CAGTCGGAGCTAGGAAGGAA-3¢. Isolation of plasma membrane, intact chloroplasts, stroma and thylakoids The plasma membrane fraction of Arabidopsis was isolated as prev...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Acylation of lysophosphatidylcholine plays a key role in the response of monocytes to lipopolysaccharide ppt
... the cell walls of Gram-negative bacteria, is an important microbial molecular pattern that initiates in ammatory and coagulation reactions as part of the host innate immune response to infection. ... utilized two acyltransferase inhibitors. SK&F 98625, originally described as a CoA-independent acyltransferase inhibitor [16], was included as it inhibits both LPCAT and LPAAT in MonoMa...
Ngày tải lên: 31/03/2014, 01:20
Báo cáo khoa học: "Partially Specified Signatures: a Vehicle for Grammar Modularity" pdf
... conforming to a detailed set of desiderata. 1 Introduction Development of large scale grammars for natural languages is an active area of research in human language technology. Such grammars are ... theoretical linguis- tic research, but also for natural language applica- tions such as machine translation, speech genera- tion, etc. Wide-coverage grammars are being de- veloped for various...
Ngày tải lên: 08/03/2014, 02:21
Báo cáo khoa học: Mycobacterium tuberculosis ClpC1 Characterization and role of the N-terminal domain in its function ppt
... ClpC1D1 aggregated at 43 °C (data not shown). In addition to measuring aggregation as a change in turbidity, we also assayed luciferase activity prior to and after heating it in the absence and pres- ence ... Kar, Deepa Sikriwal*, Parthasarathi Rath*, Rakesh K. Choudhary and Janendra K. Batra Immunochemistry Laboratory, National Institute of Immunology, New Delhi, India Chaperone prot...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: "Medical emergency teams: deciphering clues to crises in hospitals"
... for Healthcare Improvement and the Society for Critical Care Medicine have been promoting rapid response teams and METs. In North America and in Europe, there now appears to be a rapid increase in ... colleagues provide data regarding the temporal pattern of METs. They describe a diurnal variation to crises that strongly suggests hospital processes may systematically ignore (and fin...
Ngày tải lên: 25/10/2012, 10:45
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle ppt
... Pharmacology, University of Calgary, Alberta, Canada 2 School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia Long-range signaling Biological organs display coordinated ... (1993) Inositol trisphosphate and calcium signalling. Nature 361, 315–325. 21 Callamaras N, Marchant JS, Sun XP & Parker I (1998) Activation and co-ordination of InsP3-mediated elemen- tary C...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium pptx
... Ca 2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium Masayuki Yamashita Department of Physiology I, Nara Medical University, Kashihara, Japan Structural organization of intracellular Ca 2+ stores ... space, because I C can pass the plasma membrane capacita- tively. Thus, the current loop can be closed via the extracellular space and the plasma membrane. Thi...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Animal models of amyloid-b-related pathologies in Alzheimer’s disease docx
... JC, Paul SM & Holtzman DM (2001) Peripheral anti -A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer’s disease. Proc Natl Acad ... learning cages where animals carrying transponders are housed in groups and trained in learning corners. Each individual is recognized by a distinct antenna signal [161]. Standa...
Ngày tải lên: 16/02/2014, 09:20