Estrogen Receptor (ER) doc
Estrogen Receptor (ER) doc
... Phức hợp estrogen - receptor sau đó gắn lên vị trí đặc hiệu trên DNA (specific DNA sites), được gọi là yếu tố đáp ứng estrogen (estrogen response elements - ERE) Estrogen Receptor (ER) ... không có mặt của estrogen, các ER này bị bất hoạt(inactive) và không có tác dụng lên DNA. Nhưng khi có sự hiện diện của estrogen thì các phân tử estrogen sẽ gắn lên receptor củ...
Ngày tải lên: 29/07/2014, 02:21
Báo cáo y học: "Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population" docx
... of metalloproteinase 3 (TIMP3), interleukin-1 receptor (IL1R), and the estrogen receptor [6]. The human estrogen receptor (ER) has two isoforms: ER-α and ER-β. The former isoform is a ligand-activated ... Jr: Selective expression of estrogen receptor alpha and beta iso- forms in human pituitary tumors. J Clin Endocrinol Metab 1998, 83:3965-3972. 8. Evans RM: The steroid and...
Ngày tải lên: 09/08/2014, 01:23
Tài liệu Color Atlas of Pharmacology (Part 7): Drug-Receptor Interaction doc
... agonists AntagonistAgonist Receptor Antagonist occupies receptor without con- formational change Agonist selects active receptor conformation Antagonist Agonist Rare spontaneous transition Antagonist selects inactive receptor conformation inactive Efficacy Potency Concentration ... license. Drug -Receptor Interaction 65 Amino acids D. Protein synthesis-regulating receptor A. G-Prot...
Ngày tải lên: 26/01/2014, 19:20
Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... acetylcholine receptor subtypes; pharmacology; venom peptides; Xenopus oocytes. Neuronal nicotinic acetylcholine receptors The nicotinic acetylcholine receptor family The nicotinic acetylcholine receptor ... in oocyte-expressed a7 receptors (Table 1), suggesting that the a7* receptors in intracardiac ganglion neurons are not homomers, or that the heterologously expressed a7 receptor d...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Dopamine D4 receptor oligomerization – contribution to receptor biogenesis doc
... max] [Receptor- YFP]/ [Receptor- Rluc] 0.02 0.00 05 D 2L R-Rluc/eYFP D 2L R-Rluc/D 2L R-YFP D 4.7 R-Rluc/D 4.7 R-YFP D 4.4 R-Rluc/D 4.4 R-YFP D 4.2 R-Rluc/D 4.2 R-YFP D 4.2 R-Rluc/YFP D 4.2 R-Rluc/D 4.2 R-YFP D 4.2 R-Rluc/D 4.7 R-YFP D 4.2 R-Rluc/D 4.4 R-YFP D 4.4 R-Rluc/D 4.7 R-YFP D 4.2 R-Rluc/D 4.7 R-YFP D 4.7 R-Rluc/eYFP D 4.7 R-Rluc/D 4.7 R-YFP D 2L R-Rluc/eYFP D 2L R-Rluc/D 2L R-eYFP D...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx
... binds to the androgen receptor and estrogen receptors a or b [38–41]. DHEA at 30 nm is sufficient to activate transcription of estro- gen receptor b to the same degree as estrogen at its circulating ... by DHEA is independent of androgen and estrogen receptors DHEA is converted to sex steroids, and cervical cancer cell lines have estrogen and progesterone receptors [1,22]; therefor...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: The purine derivative PI-55 blocks cytokinin action via receptor inhibition docx
... other two cytokinin receptors. This corroborates the differences in cytokinin binding sites of individual receptors and indicates that the preparation of a ‘universal’ cytokinin receptor antagonist ... anticytokinin that acts at the receptor level. Specific substitutions in ortho- and meta- positions of the aromatic sidechain of BA resulted in altered perception by the cytokinin receptors...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo Y học: Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function doc
... 1 receptor; melanoma; loss-of- function mutations; functional coupling; structure-function relationships. G protein-coupled receptors (GPCRs) constitute the largest family of cell surface receptors ... forskolin; GPCR, G protein coupled receptor; GCNC, giant congenital nevus cells; HMC, human melanoma cells; MC1R, human melanocortin 1 receptor; mc1r, mouse melanocortin 1 receptor; aMSH,...
Ngày tải lên: 17/03/2014, 10:20
Coffee consumption modifies risk of estrogen- receptor negative breast cancer pdf
... average daily alcohol consumption (g/day). Significant P values are in bold. ER, estrogen receptor; PR, progesterone receptor. Li et al. Breast Cancer Research 2011, 13:R49 http://breast-cancer-research.com/content/13/3/R49 Page ... medium, high) and average daily alcohol consumption (continuous, in g/day)). ER, estrogen receptor; PR, progesterone receptor. Li et al. Breast Cancer R...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: An estrogen receptor a suppressor, microRNA-22, is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples pptx
... Korach KS (2006) Estrogen receptors and human disease. J Clin Invest 116, 561–570. 39 Clarke RB, Anderson E & Howell A (2004) Steroid receptors in human breast cancer. Trends Endocrinol Metab ... the authors. MicroRNA-22 and estrogen receptor a J. Xiong et al. 1694 FEBS Journal 277 (2010) 1684–1694 ª 2010 The Authors Journal compilation ª 2010 FEBS An estrogen receptor a suppres...
Ngày tải lên: 22/03/2014, 21:20