Chapter 114 Molecular Mechanisms of Microbial Pathogenesis (Part 4) potx

... mediate colonization of epithelial surfaces, particularly adherence to structures like fibronectin, laminin, Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 4) Flagella are ... Binding of the highly conserved Staphylococcus aureus surface protein clumping factor A (ClfA) to fibrinogen has been implicated in many aspects of pathogenesis. The co...

Ngày tải lên: 07/07/2014, 04:20

... Mechanisms of Microbial Pathogenesis (Part 1) Harrison's Internal Medicine > Chapter 114. Molecular Mechanisms of Microbial Pathogenesis Molecular Mechanisms of Microbial Pathogenesis: ... decades, molecular studies of the pathogenesis of microorganisms have yielded an explosion of information about the various microbial and host molec...

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... matrix proteins Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 2) Table 114- 1 Examples of Microbial Ligand-Receptor Interactions Microorganism Type of Microbial Ligand ... cell–specific C-type lectin. antigens Bacterial Pathogens Neisseria spp. Pili Membrane cofactor protein (CD46) Pseudomonas aeruginosa Pili and flagella...

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... detail of the bacterial surface structures. (Images courtesy of Dr. Martin Lee and Dr. Milan Bajmoczi, Harvard Medical School.) Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part ... micrographic images of fixed cells of Pseudomonas aeruginosa. Flagella (A) and pili (B) projecting out from the bacterial poles can be seen. C and D . Atomic force...

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... Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 5) Numerous virus–target cell interactions have been described, ... several examples of microbial biofilm growth associated with human disease. Many other pathogens can form biofilms during in vitro growth, and it is increasingly accepted that this mode of growth ... grow. The growth of viral path...

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... Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 6) Encounters with Epithelial Cells Over the past decade, ... epithelial cells (Fig. 114- 2); the bacteria often use specialized surface structures that bind to receptors, with consequent internalization. However, the exact role and the importance of this process ... ingestion and killing by professio...

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... (LBP), transfers LPS to Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 7) Encounters with Phagocytes Phagocytosis and Inflammation Phagocytosis of microbes is a major ... to our understanding of molecular mechanisms of microbial pathogenesis (Fig. 114- 3). One of the best-studied systems involves the interaction of LPS from gram-neg...

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... Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 8) GPI-anchored receptors do not have intracellular signaling ... through a series of signal- transducing molecules (Fig. 114- 3) that lead to nuclear translocation of the transcription factor nuclear factor κB (NF-κB), a master-switch for production of important ... is now appreciated that some o...

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... of diseases like toxic shock syndrome and scarlet fever. A number of Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 9) Fungal pathogens almost always take advantage of ... toxin production is one of the best-characterized molecular mechanisms of pathogenesis, while host factors such as IL-1, TNF-α, kinins, inflammatory proteins, products...

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... leads to fever, muscle proteolysis, and other effects, as noted Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 10) Invasion Many diseases are caused primarily by pathogens ... importance of this structure in pathogenesis. Host Response The inflammatory response of the host is critical for interruption and resolution of the infectious process b...

Ngày tải lên: 07/07/2014, 04:20