Chapter 105 Malignancies of Lymphoid Cells (Part 12) ppsx
Chapter 105. Malignancies of Lymphoid Cells (Part 12) ppsx
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 12)
Table 105-
10 Clinical Characteristics of Patients with Common Types
of Non-Hodgkin's Lymphomas ... "basket" cells, nuclear
remnants of cells damaged by the physical shear stress of making the blood smear.
If cytogenetic studies are performed, trisomy 12 is found in 25–30% of patients. ......
Chapter 105. Malignancies of Lymphoid Cells (Part 21) ppsx
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 21)
Rare patients with localized early stage mycosis fungoides can be cured
with radiotherapy, often total-skin electron ... "flower" cells (Fig. 105- 10).
Figure 105- 10
chemotherapy regimens can result in objective responses, true complete
remissions are unusual, and the median survival of patients i...
Chapter 105. Malignancies of Lymphoid Cells (Part 1) docx
...
lymphoma
Chapter 105. Malignancies of
Lymphoid Cells
(Part 1)
Harrison's Internal Medicine > Chapter 105. Malignancies of Lymphoid
Cells
Malignancies of Lymphoid Cells: Introduction ... Introduction
Malignancies of lymphoid cells range from the most indolent to the most
aggressive human malignancies. These cancers arise from cells...
Chapter 105. Malignancies of Lymphoid Cells (Part 2) ppt
...
lymphoid tissue; NK, natural killer; WHO, World Health Organization.
Malignancies in bold occur in at least 1% of patients.
Source: Adapted from Harris et al.
Chapter 105. Malignancies of ...
Chapter 105. Malignancies of
Lymphoid Cells
(Part 2)
Non-Hodgkin's lymphomas were separated from Hodgkin's disease by
recognition of the Sternberg-Reed cel...
Chapter 105. Malignancies of Lymphoid Cells (Part 3) pptx
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 3)
General Aspects of Lymphoid Malignancies
Etiology and Epidemiology
The relative frequency of the various lymphoid malignancies ... frequency of the various lymphoid malignancies is shown in
Fig. 105- 1. Chronic lymphoid leukemia (CLL) is the most prevalent form of
leukemia in western countries. I...
Chapter 105. Malignancies of Lymphoid Cells (Part 4) pptx
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 4)
The incidence of non-Hodgkin's lymphomas and the patterns of expression
of the various subtypes differ ... transfusion-transmitted virus (Chap. 181).
Table 105-
4 Infectious Agents Associated with the Development of
Lymphoid Malignancies
Infectious Agent Lymphoid Malignancy
Note: CNS, centra
l ner...
Chapter 105. Malignancies of Lymphoid Cells (Part 5) pdf
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 5)
Table 105-
5 Diseases or Exposures Associated with Increased Risk of
Development of Malignant Lymphoma
Inherited ... activation of a series of transcription
factors, the cell first becomes committed to the lymphoid lineage and then gives
rise to B and T cells. About 75% of all lymphoid leukemias and 90...
Chapter 105. Malignancies of Lymphoid Cells (Part 6) pot
... Chapter 105. Malignancies of
Lymphoid Cells
(Part 6)
Figure 105- 3
In the case of diffuse large B cell lymphoma, the translocation t(14;18)
occurs in ~30% of patients and ... stimulus.
Malignancies of lymphoid cells are associated with recurring genetic
abnormalities. While specific genetic abnormalities have not been identified for all
subtypes of lympho...
Chapter 105. Malignancies of Lymphoid Cells (Part 7) docx
... frame.
Chapter 105. Malignancies of
Lymphoid Cells
(Part 7)
Table 105- 6 presents the best documented translocations and associated
oncogenes for various subtypes of lymphoid malignancies. ... the identification
of patterns of gene expression with diagnostic and/or prognostic significance, and
the identification of new therapeutic targets. Recognition of pa...
Chapter 105. Malignancies of Lymphoid Cells (Part 8) potx
...
prognostic significance and should not be used to assign a higher stage.
Table 105- 7 Staging of Typical B Cell Lymphoid Leukemia
Stage Clinical Features Median
Survival, Years
establish ... hypogammaglobulinemia benefit from regular (monthly) γ globulin
administration. Because of expense, γ globulin is often withheld until the patient
experiences a significant infection. Thes...