Chapter 081 Principles of Cancer Treatment (Part 15) ppsx

... motile and secretory processes occur. Microtubules are composed of repeating noncovalent multimers of a heterodimer of α and subunits of the protein tubulin. Vincristine binds to the tubulin dimer ... refractory cancers. Intravenous administration of 5FU leads to bone marrow suppression after short infusions but to stomatitis after prolonged infusions. Leucovorin augments the a...

Ngày tải lên: 07/07/2014, 01:20

... those with pancolonic involvement with ulcerative colitis), the presence of Chapter 081. Principles of Cancer Treatment (Part 2) Figure 81-1 ... Principles of Cancer Surgery Surgery is used in cancer prevention, diagnosis, staging, treatment (for both localized and metastatic disease), palliation, and rehabilitation. Prophylaxis Cancer ... incisional b...

Ngày tải lên: 07/07/2014, 01:20

... dose of therapeutic radiation exists below which the incidence of second cancers is decreased. High rates of second tumors occur in people who receive as little as 1000 cGy. Chapter 081. Principles ... breast cancer, Hodgkin's disease, head and neck cancer, prostate cancer, and gynecologic cancers. Radiation therapy can also palliate disease symptoms in a variety of...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 081. Principles of Cancer Treatment (Part 12) Direct DNA-Interactive Agents DNA replication occurs during the synthesis or S-phase of the cell cycle, with ... cause profound myelosuppression, alopecia, and pulmonary toxicity but is relatively "lymphocyte sparing." Its routine case. Thiotepa can be used for intrathecal treatment of neoplastic ... n...

Ngày tải lên: 07/07/2014, 01:20

... targets of T cell killing greatly expanded the possibilities for Chapter 081. Principles of Cancer Treatment (Part 24) Immune Mediators of Antitumor Effects The very existence of a cancer ... is testimony to the failure of the immune system to deal effectively with the cancer. Tumors have a variety of means of avoiding the immune system: (1) they are often...

Ngày tải lên: 07/07/2014, 01:20

... benefit. One of the challenges of cancer treatment is to use the various treatment modalities alone and together in a fashion that maximizes the chances for patient benefit. Cancer treatments ... attention to minimizing the toxicity of potentially toxic treatments becomes a significant goal. Irrespective of the clinical scenario, the guiding principle of cancer treatme...

Ngày tải lên: 07/07/2014, 01:20

... information for treatment planning and may determine the extent and nature of primary cancer treatment. Treatment Surgery is the most effective means of treating cancer. Today about 40% of cancer ... resection of certain tumors that would otherwise not be possible. Chapter 081. Principles of Cancer Treatment (Part 3) Staging As noted in Chap. 77, an i...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 081. Principles of Cancer Treatment (Part 4) Palliation Surgery is employed in a number of ways for supportive care: insertion of central venous catheters, control of pleural ... for recurrent pulmonary emboli, stabilization of cancer- weakened weight-bearing bones, and control of hemorrhage, among others. Surgical bypass of gastrointestinal, urinary...

Ngày tải lên: 07/07/2014, 01:20

... the target volume is often the cause of complications to tissues in the transit volume, and the minimum dose in the target Chapter 081. Principles of Cancer Treatment (Part 5) Although ... include the D 0 of the tumor (the dose required to deliver an average of one lethal hit to all the cells in a population), the D q of the tumor (the threshold dose—a measure...

Ngày tải lên: 07/07/2014, 01:20

... described in Chapter 80, successful tumors have activated biochemical pathways that lead to uncontrolled proliferation through the Chapter 081. Principles of Cancer Treatment (Part 7) Karnofsky ... providing a basis for patients to make sensible choices. Cancer Drugs: Overview and Principles for Use Cancer drug treatments are of four broad types. Conventional ch...

Ngày tải lên: 07/07/2014, 01:20