Chapter 081 Principles of Cancer Treatment (Part 10) pdf

... function of these Chapter 081. Principles of Cancer Treatment (Part 10) Integration of cell death responses. Cell death through an apoptotic mechanism requires active participation of the ... novel mechanisms of action, combinations of drugs and targeted agents may maximize the chances of affecting critical pathways in the tumor. Chemotherapeutic Agents Use...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 081. Principles of Cancer Treatment (Part 4) Palliation Surgery is employed in a number of ways for supportive care: insertion of central venous catheters, control of pleural ... for recurrent pulmonary emboli, stabilization of cancer- weakened weight-bearing bones, and control of hemorrhage, among others. Surgical bypass of gastrointestinal, urinary...

Ngày tải lên: 07/07/2014, 01:20

... endogenous regulators of the cell death pathway are activated (Fig. 81-3). Figure 81-3 Chapter 081. Principles of Cancer Treatment (Part 9) Following demonstration of activity in animal ... improve their use. A general view of how cancer treatments work is that the interaction of a chemotherapeutic drug with its target induces a "cascade" of further...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 081. Principles of Cancer Treatment (Part 17) Prostate cancer is classically treated by androgen deprivation. Diethylstilbestrol (DES) acting as an estrogen at the level of the ... discovery of the candidate drug is the a priori importance of the target in the biology of the tumor, rather than the initial detection of drug candidates based on the phe...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 081. Principles of Cancer Treatment (Part 23) Mucositis Irritation and inflammation of the mucous membranes particularly afflicting ... growth factor, a member of the fibroblast growth factor family, is effective in preventing severe mucositis in the setting of high-dose chemotherapy with stem cell treatment. Females experience ... use of cosmetic resour...

Ngày tải lên: 07/07/2014, 01:20

... benefit. One of the challenges of cancer treatment is to use the various treatment modalities alone and together in a fashion that maximizes the chances for patient benefit. Cancer treatments ... attention to minimizing the toxicity of potentially toxic treatments becomes a significant goal. Irrespective of the clinical scenario, the guiding principle of cancer treatme...

Ngày tải lên: 07/07/2014, 01:20

... those with pancolonic involvement with ulcerative colitis), the presence of Chapter 081. Principles of Cancer Treatment (Part 2) Figure 81-1 ... Principles of Cancer Surgery Surgery is used in cancer prevention, diagnosis, staging, treatment (for both localized and metastatic disease), palliation, and rehabilitation. Prophylaxis Cancer ... incisional b...

Ngày tải lên: 07/07/2014, 01:20

... information for treatment planning and may determine the extent and nature of primary cancer treatment. Treatment Surgery is the most effective means of treating cancer. Today about 40% of cancer ... resection of certain tumors that would otherwise not be possible. Chapter 081. Principles of Cancer Treatment (Part 3) Staging As noted in Chap. 77, an i...

Ngày tải lên: 07/07/2014, 01:20

... the target volume is often the cause of complications to tissues in the transit volume, and the minimum dose in the target Chapter 081. Principles of Cancer Treatment (Part 5) Although ... include the D 0 of the tumor (the dose required to deliver an average of one lethal hit to all the cells in a population), the D q of the tumor (the threshold dose—a measure...

Ngày tải lên: 07/07/2014, 01:20

... dose of therapeutic radiation exists below which the incidence of second cancers is decreased. High rates of second tumors occur in people who receive as little as 1000 cGy. Chapter 081. Principles ... breast cancer, Hodgkin's disease, head and neck cancer, prostate cancer, and gynecologic cancers. Radiation therapy can also palliate disease symptoms in a variety of...

Ngày tải lên: 07/07/2014, 01:20