báo cáo hóa học:" Chloroquine is a potent inhibitor of SARS coronavirus infection and spread" docx

... Seidah 2 and Stuart T Nichol* 1 Address: 1 Special Pathogens Brach, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia, ... with MV and EB participated in the plan- ning of the experiments, review and interpretation of data and critical review of the manuscript. All authors read and approved the...

Ngày tải lên: 20/06/2014, 04:20

... and FACS analysis. BE performed data acquisition from the immunofluorescence experiments. PR and TK provided critical reagents and revised the manuscript critically. NS and SN along with MV and ... WJ, Farzan M, Marasco WA: Potent neutralization of severe acute respira- tory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association. Proc Natl...

Ngày tải lên: 19/06/2014, 08:20

... adhesion and activation. Three such molecules, LAPP (an approximately 13 kDa leech antiplatelet protein isola- ted from Haementeria of cinalis) and calin and sara- tin (approximately 65 kDa and 12 kDa ... alimentary habit of hemato- phagy. The presence of anticoagulants in the salivary glands of the leech, Hirudo medicinalis, was originally discovered by Haycraft in 1884 and...

Ngày tải lên: 30/03/2014, 09:20

... rationale for criminalisation is the criminal law goal of retribution and punishment – but that is a poor and distorted aim for public health purposes; and • criminalisation is in general warranted ... of criminalisation is to enhance stigma, fear, isolation, and the dread of persecution and ostracism that drives people away from treatment. In conclusion, we submit t...

Ngày tải lên: 20/06/2014, 08:20

... TAGAATTCGCGACAGGAGCCATA simEXX4F TAGAATTCGACGCCTTCCAGTC DNA-shift assay P X4 simEXX4R TAGAATTCTCAGAACATCGTCC SR2ExXF AAATCTAGATCAAGCCAGTGCTG DNA-shift assay P R2Ex SR2ExXR TTTGAATTCTTGACCACCACTTC PSR2F ... P A7 simA7R ATAAGCTTGTCGATACCGATCTTC PEx2F ACTTCCCAGAAGTA DNA-shift assay P Ex2 PEx2R AGAGGGCAGTAGAC PR3F TTTCTAGATGCACCCGATCCTC DNA-shift assay P SR3 PR3R GAACAGGATTCGCATGAGTACT D4For TA...

Ngày tải lên: 21/06/2014, 17:20

... 51:189-197. 27. A ssaoui Y, Zeggwagh AA, Zekraoui A, Abidi K, Abouqal R: Vali- dation of a behavioral pain scale in critically ill, sedated, and mechanically ventilated patients. Anesth Analg 2005, 101:1470-1476. 28. ... acquisition of data. NM helped to draft the manuscript, and participated in the acquisi- tion of data. AZ participated in the coordination of the study. AAZ p...

Ngày tải lên: 25/10/2012, 10:35

... as follows; Slc1 2a2 antisense, 5¢-ATCTTCACAAGAAAAAT CACCTGGTACCAAGGATGT; Slc1 2a2 sense, 5¢-ACAT CCTTGGTACCAGGTGATTTTTCTTGTGAAGAT. All experimental protocols described in this study were approved by ... 110, 151–164. 26 Tomari S, Nagahama H, Shu Y, Hoshi S, Nakayama K, Nakayama KI & Nagata M (2002) Glomerular dif- ferentiation in p27 and p57 double-mutant metanephroi. Anat Embryol 206,...

Ngày tải lên: 07/03/2014, 17:20

... ich Fig. 1. Characterization and c omparison of l arge and small dj2 mRNAs. (A) Schematic re presentation and sequence comparison of t he m onkey large dj2 cDNA and human small dj2 cDNA (B). Northern ... potent partner of hsc70 in mammalian cells Petros Bozidis, Ioannis Lazaridis, Gerassimos N. Pagoulatos and Charalampos E. Angelidis Laboratory of General Biology, Medical...

Ngày tải lên: 17/03/2014, 17:20

... reactive, equilibria that drive quasispecies expansion and generates escape mutation. Replicative homeostasis explains both viral kinetics and the enigma of RNA quasispecies stability and provides a rational, ... viral hepatitis ranges from asymptomatic healthy chronic carriage to fulminant liver disease and death within days, is far more rationally explained on the basis of...

Ngày tải lên: 20/06/2014, 04:20

... centralizer if L is a quadratic homogeneous mapping, that is quadratic and L(l a) =l 2 L (a) for all a ∈ A and l Î ℂ and L(ab)=L (a) b 2 for all a, b ∈ A , and a mapping R : A → A is a quadratic ... right centralizer if R is a quad- ratic homogeneous mapping and R(ab) =a 2 R(b) for all a, b ∈ A . Also a quadratic dou- ble centralizer of an algebra...

Ngày tải lên: 20/06/2014, 22:20