Báo cáo sinh học: " Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats" doc
Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx
... domain binding motif in their C-termini.
PDZ domains have been established as sites for protein–protein inter-
action and play a central role in organizing diverse cell signaling assem-
blies. In ... abundant
protein interaction domains in organisms from bacteria
to mammals, and have been implicated in various pro-
cesses, including clustering, targeting and routing of
their binding...
Báo cáo khoa học: Androgen receptor function is modulated by the tissue-specific AR45 variant ppt
... to
inhibit its function [21]. The progesterone receptor exists
as two isoforms, PRA and PRB, differing by the length
of the N-terminal end and originating from translation
reinitiation at an internal ... composed of a
unique N-terminal extension linked to the DNA-bind-
ing domain (DBD), hinge region and ligand-binding
domain (LBD) of the AR. The restricted expression
pattern, the inhibitory...
Báo cáo khoa học: Induction of PAI-1 expression by tumor necrosis factor a in endothelial cells is mediated by its responsive element located in the 4G/5G site ppt
... (1996) Distri-
bution and regulation of plasminogen activator inhibi-
tor-1 in murine adipose tissue in vivo. Induction by
tumor necrosis factor- alpha and lipopolysaccharide.
J Clin Invest 97, ... synthesis of plasminogen activator inhibitor type-1
by precursors of insulin. A potential risk factor for vas-
cular disease. Circulation 89, 321–330.
7 Brown NJ, Kim KS, Chen YQ, Blevin...
Báo cáo y học: "Maitake Mushroom Extracts Ameliorate Progressive Hypertension and Other Chronic Metabolic Perturbations in Aging Female Rats"
... with
refined CHO ingestion and/or aging is uncertain,
because the elevated SBP may relate to a number of
perturbed underlying regulating mechanisms that
include augmented catecholamine levels ...
did likewise. Somewhat surprising was the finding
that Fraction D enhanced insulin sensitivity. It is not
clear why this happened. Fraction D is known pri-
marily for its immune enhanc...
Tài liệu Báo cáo khoa học: Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast doc
... ctt1, encoding catalase, and apt1, encoding
a 25 kDa protein, but not that of gpx1, encoding glutathione peroxidase,
was indistinguishable in four ubiquinone-deficient mutants, indicating that
the ... of cells,
GFP fluorescence produced by Coq7–GFP
fusion proteins and mitochondrial staining
by MitoTracker in strain LN902 expressing
Coq7–GFP are shown.
Coq7 in fission yeast R. Miki et...
Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx
... (k
cat
¼ 5.1)
is favored by a factor of 20 over the dehydration reac-
tion (k
cat
¼ 0.26) which is consistent with the main
role of AUH in leucine catabolism, the hydration of
3-MG-CoA. Comparing the ... gene. This indi-
cated that AUH, in addition to its RNA binding func-
tion, must play an important role in leucine catabolism.
AUH was overproduced in E. coli and characterize...
Tài liệu Báo cáo Y học: Solution structure of the mEGF/TGFa44250 chimeric growth factor doc
... be induced by spin diffusion
and then soften all distance constraints accordingly. In
effect, this allows for the uncertainty in converting NOE
volumes into distances that remains despite having
optimized ... annealing.
Epidermal growth factor (EGF) [1,2] and transforming
growth factor alpha (TGFa) [3] are members of a family that
also includes heparin-binding EGF-like growth...
Báo cáo khoa học: Interaction between catalytically inactive calpain and calpastatin Evidence for its occurrence in stimulated cells docx
... the intensity of calpain staining increased 7–
8-fold, indicating that the protease was now mainly
present in the high-affinity form.
In these conditions, although the highest amount of
calpain is ... role
of the two Ca
2+
-binding sites recently identified in this
catalytic domain is still to be defined [23]. More
intriguing is the possibility of detecting calpain activa-
tion in...
Báo cáo khoa học: "On the Evaluation and Comparison of Taggers: the Effect of Noise in Testing Corpora." doc
... Voutilainen, A. 1997. Compar-
ing a Linguistic and a Stochastic Tagger. In
Pro-
ceedings of joint E/A CL meeting.
1001
On the Evaluation and Comparison of Taggers: the Effect of
Noise in Testing ... correct in or-
der to compare it with the tagger output. This
is usually done by assuming that the disam-
biguated test corpora being used contains the
right POS disambiguation....
Báo cáo Y học: Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells docx
... 37 °C in an incubator containing 5%
CO
2
and maintained by regular passage in Dulbecco’s
minimal essential medium (supplemented with 10% heat-
inactivated fetal bovine serum, 2 m
ML
-glutamine ... or
ATP depleting agents, or when both nucleotide-binding
sites are inactivated by mutations [18]. The upshift of UIC2
binding in the presence of substrates/modulators is applied
as an in...