... by the anchor of the tree (the verb) but by the complement of the anchor (the adjective). The verb form feature must therefore be percolated from the adjective phrase to the subject. The ... becomes the head of the tree resulting from the adjunction. In modifier auxiliary trees, the anchor is not the head of the tree, and the sub- tree headed by th...
Ngày tải lên: 08/03/2014, 21:20
... span a much larger range for the vowel inventories than for the consonant inventories. The significance of the difference in the nature of the distribution of RRs for the vowel and the conso- nant ... measure of redun- dancy is almost an invariance over the consonant inventories of the world’s languages. The observa- tion is important since it can shed enough...
Ngày tải lên: 17/03/2014, 04:20
Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
... of CaM to the Ca 2+ -CaM-binding domain of nNOS. CaM is not only essential for the operation of nNOS and the other NOS isoforms, but is also the regulatory protein for a variety of other enzymes, ... Ca 2+ -CaM, and is one of the more active of the known peptide inhibitors of nNOS. Results Cupiennin 1a was tested for the ability to inhibit nNOS, using an assay th...
Ngày tải lên: 23/03/2014, 09:21
Báo cáo khoa học: Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer potx
... some subunits can exchange but others cannot, may be explained by the greater sensitivity of the exchange experi- ments. Indeed, careful analysis of both the bis-ANS titrations and the labelling ... (yielding F adj ), the quenching curve was then fitted with the Stern– Volmer equation (eqn 5), where F o is the fluorescence of the label in the absence of quencher, K Q i...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: Global shape and pH stability of ovorubin, an oligomeric protein from the eggs of Pomacea canaliculata pot
... ovorubin is an anisometric particle with a major axis of 130 A ˚ and a minor one varying between 63 and 76 A ˚ . The particle shape was not significantly affected by the absence of the cofactor astaxanthin. ... Mechanisms of spectral shifts in lobster carote- noproteins. The resonance raman spectra of ovoverdin and the crustacyanins. Biochim Biophys Acta 576, 176– 191. Stru...
Ngày tải lên: 07/03/2014, 06:20
Báo cáo khoa học: Glycosphingolipids in Plasmodium falciparum Presence of an active glucosylceramide synthase pot
... with the mobility of an authentic standard of C 18 - sphinganine, the other one (R F 0.38) migrating slightly above, would correspond to C 20 -sphinganine. A similar result was obtained when the ... confirm that the de novo biosynthetic pathway of ceramides is active in this parasite. Nevertheless, the last step of the ceramide biosynthesis, involving the dehydrogenatio...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt
... distant from the side chain of Arg78. The side chain of Arg78 is less well defined, as in the case of aqueous solution, because of the absence of interactions with the s ide chains of A sp81 (in the ... ey characteristic of the structure of the native epitope in Me 2 SO is the presence of a large number of electrostatic interactions, especially in the ce...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal b-N-acetylhexosaminidase pot
... Department of Structure and Function of Proteins, Institute of Nanobiology and Structural Biology of GCRC, Academy of Sciences of the Czech Republic and Faculty of Sciences of the University of South ... the diffusion and access of the substrate to the bind- ing site of the enzyme, as well as the release of the prod- ucts. In conclusion, in this paper w...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma pdf
... mutant), the 3¢-UTR and mutant 3¢-UTR fragments of PPP6C tran- scripts amplified by RT-PCR were inserted into the vector backbone downstream of the EGFP gene between the BamHI and EcoRI sites of ... acquisition and analysis software was used to quan- tify band intensities. Antibodies were purchased from Tian- jin Saier Biotech and Sigma-Aldrich. Statistical analysis Data are expr...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Aberrant interchain disulfide bridge of tissue-nonspecific alkaline phosphatase with an Arg433 fi Cys substitution associated with severe hypophosphatasia pdf
... ⁄ mL): lanes 1 and 6, 0; lanes 2 and 7, 0.5; lanes 3 and 8, 1.0; lanes 4 and 9, 5.0; lanes 5 and 10, 10. Lanes 1–5 and lanes 6–10 were analyzed by SDS ⁄ PAGE in the presence or absence of 2-mercaptoethanol, ... tended to inhibit the synthesis of TNSALP (R433C) induced by doxycycline. Importantly, we detected an increase in the enzyme activity of the cells concomitantly with t...
Ngày tải lên: 16/03/2014, 12:20