... that enable ras and pmt oncogenes to trans-form cultured primary cells. Mol Cell Biol 6, 887–899.48 Yanagida M, Hayano T, Yamauchi Y, Shinkawa T,Natsume T, Isobe T & Takahashi N (2004) Human fibrillarin ... inhibitor of methylation Adox. The fixed cells were stained with antibodies againstp80-coilin, which label Cajal bodies (A) , oragainst SMN, a marker for GEMS (B), and analyzed by laser-scanning ... in Adox-treated cells, EGFP–Ki-1 ⁄ 57 partially localizes to nuclear speckles, whereasin Adox-treated cells it partially localizes to GEMS,Cajal bodies, and nucleoli. The nuclear speckles areknown...