... have promising therapeutic potential for further development as a novel antimicrobial and antisepsis agent. It is interesting to note that the higher toxicity asso- ciated with fowlicidin-1 is probably ... the toxicity of fowlicidin-3 to mammalian cells As compared with b-sheet defensins, a considerably higher degree of toxicity to mammalian cells occurs with a-helical cat...
Ngày tải lên: 07/03/2014, 11:20
... infrastructure and expansion of tourist sites, and the accumulation of pesticides from agricultural activities in the island may affect the life cycle of the species. It seems to be the first record of ... Mathematisch-Naturwissenschaftliche Classe. Wien 45: 389- 426. Holthuis, L. B. (1950) The Decapoda of the Siboga Expedition. Part 10. The Palaemonidae collected by...
Ngày tải lên: 02/04/2014, 09:20
Tài liệu Báo cáo khoa học: A second independent resistance mechanism to Bacillus sphaericus binary toxin targets its a-glucosidase receptor in Culex quinquefasciatus docx
... is located in this part of the receptor. To date, no informa- tion is available on the binding motif for the Bin toxin, and this is the first evidence mapping its location to the receptor’s N-terminal ... its ortholog from other insect species. These results are consistent with the lack of production of the Cqm1 receptor in the CqRL1 ⁄ 2362 larvae being the...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Identification of yeast aspartyl aminopeptidase gene by purifying and characterizing its product from yeast cells potx
... pre- cursor, they are probably located in the cytosol. There- fore, aspartyl aminopeptidase activity may be related to the metabolism of cytosolic peptides, particularly during the final step in their ... belong to the M18 family of metal- loprotease, comprise 12 identical subunits, and the activity of these enzymes is inhibited by EDTA [4,5]. These two enzymes may be related e...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Molecular cloning, expression analysis and functional confirmation of ecdysone receptor and ultraspiracle from the Colorado potato beetle Leptinotarsa decemlineata pdf
... C. suppressalis and S. exigua. The aim of this study is to examine the SAR of ecdysone agonists for the molecular interaction with the molting hormone receptor. Here, we report (a) the determin- ation ... as agonists of 20E in C. suppressalis by binding to EcR ⁄ USP, there is a possibility that different mecha- nisms, such as neurotoxicity and the existence of other rece...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Identification, cloning and characterization of two thioredoxin h isoforms, HvTrxh1 and HvTrxh2, from the barley seed proteome pot
... are distributed in these tissues. HvTrxh1 from all three tissues is observed. The relative intensity of the two HvTrxh1 spots from the different tissues varies (Fig. 1), suggesting that the degree ... in this area, however, were observed on the 2D Western blot with the antibody to wheat thioredoxin h. This suggests that the antibody does not recognize these isoforms be...
Ngày tải lên: 23/03/2014, 17:22
Báo cáo khoa học: Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand pot
... in the binding pocket. The average B-factor for atoms in the peptides is higher than the average B-factor for atoms in the protein (Table 2), which again may be a reflection of the mobility of the peptide ... the ASU: chains C (TPR) and I (peptide) (Fig. 4A), for which the electron density for the peptide is the clearest, and the confidence in the conformation of...
Ngày tải lên: 29/03/2014, 08:20
Báo cáo khoa học: Molecular cloning and functional expression of a gene encoding an antiarrhythmia peptide derived from the scorpion toxin pptx
... Publishers, the Nether- lands. 6. Couraud, F., Jover, E. & Dubois, J.M. (1982) Two types of scorpion toxin receptor sites, one related to the activation, the other to the inactivation of the ... that the net charge of the toxins is important to define the degree of toxicity of the peptides. Apparently, the positively charged toxins have lower LD 50 values, in ot...
Ngày tải lên: 31/03/2014, 09:20
Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... behaviour after dilution to 6 lgÆmL )1 indicate that dissociation of the tetramer to the dimer is a slowly progressing process. This is supported by the kinetic behaviour of the recombinant enzyme ... rhTLK1 is diluted from high storage concentrations to low assay concentra- tions of 2–3 ngÆmL )1 , which is below the limit for the ATP tetramerization effect, the...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Human Cdc45 is a proliferation-associated antigen pdf
... exclusively present in the nucleus from G 1 to G 2 , but was uniformly distributed throughout the cell interior after breakdown of the nuclear membrane in mitosis (Fig. 1C). Consistent with our previous ... cells [25]. These findings led us to investigate whether the human replication factor Cdc45 is also downregulated when human cells exited from the cell cycle and ent...
Ngày tải lên: 19/02/2014, 00:20