Báo cáo hóa học: " Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells" ppt

... augments H. pylori- induced cell death and DNA fragmentation in gastric epithelial cells To investigate the relations of PAR-2 expression, cell death, and DNA fragmentation, cells were transfected with ... the role of PAR-2 on H. pylori-induced cell death was investigated by determining cell viability, DNA fragmentation, and the activation of MAPK...

Ngày tải lên: 18/06/2014, 16:20

... critical role in the down-regulation of T cell responses. Its inhibition may restrict T cell activation during both the initiation and progression of the antitu- mor response. Thus, blockade of CTLA-4 ... roles in the formation and maintenance of tumor vasculature and the progression of cancer. VEGF and PDGF bind their corresponding receptors to trigger recep- tor...

Ngày tải lên: 18/06/2014, 15:20

... to the wild- type. Increasing Na + affinities at increasing pH and decreasing Na + concentrations for half maximal inhibition with increasing pH indicates improved Na + binding at elevated pH ... resulted in the formation of colonies, whereas E. coli EP432 harbouring pSK could not sustain growth. Analytical procedures The protein content of samples was determined according to the bicin...

Ngày tải lên: 08/03/2014, 23:20

... deleterious effects of a damaging insult. The emerging mechanisms of ERK1/2-mediated neuroprotection may involve transcrip- tional regulation and/ or direct inhibition of cell death machinery. Keywords: ... ERK1/2 to inhibit apoptosis of infected Ó FEBS 2004 Role of ERK1/2 in neuronal survival (Eur. J. Biochem. 271) 2051 MINIREVIEW Role of extracellular signal regulated...

Ngày tải lên: 30/03/2014, 14:20

... with a single intraperitoneal injection of SV119, conventional chemotherapy, or both. Twenty-four hours later, tumors were harvested and minced to 1 mm and digested in a RPMI buffer containing 1 ... considerable interest in stimulating apoptosis and inhibiting survival machinery as components of cancer therapy [4-6]. Many oncogenic transformations result from the inactivation or...

Ngày tải lên: 18/06/2014, 15:20

... self-esteem and because, in certain countries such as the USA, remaining in full-time employment is an important determinant of obtaining insurance for reim- bursement of treatment costs. Again, the ... (p < 0.05; Wilcoxon rank test). A sus- tained reduction in EDSS score of > 1 point was observed in fifteen patients (5.2%) and a sustained increase of > 1 point i...

Ngày tải lên: 18/06/2014, 19:20

... were to examine the effects of muscle fatigue on gait characteristics under single and dual-task conditions in young and older adults and to determine the impact of muscle fatigue on dual-t ask ... subjective levels of fatigue increased monotonically with time. The mean heart rate during the walking task was almost constant until120minfromthebeginning,andittendedto increase...

Ngày tải lên: 19/06/2014, 08:20

... zones for eyeblink conditioning in human [110]. Cerebellar circuits are also involved in the timing and extinction of condi- tioned eyeblink responses. It should be mentioned here that regarding ... associations and tuning of the magnitudes of muscle activities. An overview of recent advances in our u nderstandi ng of the contribution of cerebellar circuitry in the ela...

Ngày tải lên: 19/06/2014, 08:20

... Conclusions: The pre- valence of OAB in this population is under-diagnosed and under-treated. Key words: overactive bladder, OAB, incontinence, male, urology, veterans INTRODUCTION Recent international ... Recent international population and non-population studies reported overactive bladder (OAB) in 10-17% of the adult population, depending on sex. 1,2,3,4 In the U.S.,...

Ngày tải lên: 25/10/2012, 11:35

... determined by Bradford’s method [25], with BSA as the standard. Construction of the recombinant plasmid pADC-8 and parasite transfection A cDNA fragment containing the complete coding region of ... promoter region of pRIBOTEX and related vectors induces the transcrip- tion of genes cloned downstream of the promoter and their chromosomal integration [19]. After 48 h of transf...

Ngày tải lên: 19/02/2014, 07:20