... together with thefollicle-stimulating hormone (FSH) and the luteinizing hormone (LH) receptors, is a member of a subfamily ofseven transmembrane G-protein-coupled receptors, charac-terized by a large ... stimulating hormone; Gq-alpha,G-protein q alpha; Gs-alpha, G-protein s alpha; IP, inositolphosphate; KRH, Krebs/Ringer/Hepes; LH, luteinizing hormone; TSH, thyroid- stimulating hormone. (Received ... been described for glycoprotein hormone receptors [25–27]. The T477I has been describedas an inactivating mutation in a patient with congenitalhypothyroidism and thyroid hypoplasia [16]. Similarly,...