gene therapy for hematological disorders

... low-level gene transfer, no clear in vivo selection with chemotherapy 144 GENE THERAPY FOR HEMATOLOGICAL DISORDERS restoration of cellular and humoral immunity were documented after gene therapy. Data ... patient completely lacks the endoge- nous gene product. 150 GENE THERAPY FOR HEMATOLOGICAL DISORDERS In a murine allogeneic skin transplantation model, foreign ge...

Ngày tải lên: 10/04/2014, 22:10

... the therapeutic gene. Alternatively, dif- ferent viral vectors as well as liposomes can be used for ex vivo gene transfer. 154 GENE THERAPY FOR LIVER DISEASE For in vivo gene therapy, the therapeutic ... worldwide. For these reasons, the liver has become an important target organ for gene therapy. At the same time, certain circumstances make the liver an especially cha...

Ngày tải lên: 10/04/2014, 22:11

... retroviral-mediated gene transfer is currently the optimal gene transfer system available for use in HIV-1 gene therapy. The PRACTICAL ASPECTS OF GENE THERAPY FOR HIV 281 CHAPTER 11 Gene Therapy for HIV ... MKL, Morgan RA. Gene therapy for acquired immune deficiency syndrome. AIDS Updates 7:1–14, 1994. Yu M, Poeschla E, Wong-Staal F. Progress towards gene therap...

Ngày tải lên: 10/04/2014, 22:11

... al. (1999) A novel gene delivery system for genetic manipulation of sinusoidal )endothelial cells by triplex DNA technology: evaluation of targetability and abil- ity to stabilize triplex formation. ... acid side chains for a DNA carrier. Bioconjugate Chem. 9, 476–481. Cationic _ -Helical Peptides 11 11 From: Methods in Molecular Medicine, vol. 65: Nonviral Vectors for Gene Therapy...

Ngày tải lên: 11/04/2014, 09:59

. herpes simplex virus vectors for gene therapy in neurological diseases. Q. J. Med. 86(11), 697–702. 21. Latchman, D. S. (1994) Herpes simplex virus vectors for gene therapy. Mol. Biotechnol.. Type 1-Based Vectors for Gene Delivery to Human Hematopoietic Stem Cells Ali Ramezani and Robert G. Hawley 467 26 Semliki Forest Viral Vectors for Gene Transfer Jarmo Wahlfors and Richard A. Morgan. L....

Ngày tải lên: 11/04/2014, 10:39

... 4. Eligibility standard for oral rehydration therapy I. Patients eligible for oral rehydration therapy (receiving oral rehydration solution) 1. Those who give an informed consent and have not ... and electrolyte management is usually performed by intravenous therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for preoperative fluid and elect...

Ngày tải lên: 25/10/2012, 10:51

... vaccination in combination with imatinib therapy for a CML patient. A 51 year-old male with CML in CP, who showed a resistance against imatinib therapy for 2.5 years, began to be treated with ... Ikegame K, Hosen N, Udaka K, Yasukawa M, Ogawa H, Kawase I, Sugiyama H: Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (M...

Ngày tải lên: 26/10/2012, 09:39

... not yet been obtained in therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome (APS). We therefore compared single antiplatelet therapy and a combination ... http://www. medsci. org 16 with APS. We therefore compared single antiplatelet therapy and a combination of antiplatelet and anti- coagulation therapy for secondary prevention in isc...

Ngày tải lên: 26/10/2012, 09:48